| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clobetasol propionate perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clobetasol propionate_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.16452 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.151175 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.14905 |
| AHNAK | AHNAK nucleoprotein | 0.10038 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.100347 |
| LDHA | lactate dehydrogenase A | 0.0931144 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0835675 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0817954 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0799299 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0780203 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0731804 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0720069 |
| FKBP5 | FK506 binding protein 5 | 0.0704336 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0695995 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0668528 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0666225 |
| ASPH | aspartate beta-hydroxylase | 0.0596077 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0582683 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.0562713 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0553364 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0542183 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0535196 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0531373 |
| POTEF | POTE ankyrin domain family, member F | 0.0517348 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.0511548 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0496635 |
| STOM | stomatin | 0.048808 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0482677 |
| PON2 | paraoxonase 2 | 0.0482476 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0477214 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.045995 |
| RNF145 | ring finger protein 145 | 0.0456697 |
| LAMB1 | laminin, beta 1 | 0.043948 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0425045 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0421151 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0417057 |
| MCL1 | myeloid cell leukemia 1 | 0.0416758 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0414173 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0411089 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0407659 |
| IL6ST | interleukin 6 signal transducer | 0.0401127 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0397012 |
| FAT1 | FAT atypical cadherin 1 | 0.038948 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0376854 |
| PTMA | prothymosin, alpha | 0.0376805 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.037323 |
| HPCAL1 | hippocalcin-like 1 | 0.0368606 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0357828 |
| ENO1 | enolase 1, (alpha) | 0.0353068 |
| NRCAM | neuronal cell adhesion molecule | 0.0351875 |
| MED13L | mediator complex subunit 13-like | 0.0348266 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0346126 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0344645 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0341207 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0338733 |
| SLC45A4 | solute carrier family 45, member 4 | 0.0338669 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0333489 |
| ZBTB16 | zinc finger and BTB domain containing 16 | 0.0332125 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0329073 |
| RPGR | retinitis pigmentosa GTPase regulator | 0.0318373 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0317744 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0315675 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0309268 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0306581 |
| C3 | complement component 3 | 0.0302615 |
| PGK1 | phosphoglycerate kinase 1 | 0.0301751 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0301428 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.029527 |
| LDLRAD3 | low density lipoprotein receptor class A domain containing 3 | 0.0293452 |
| TGM2 | transglutaminase 2 | 0.0287618 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0284895 |
| PLCB4 | phospholipase C, beta 4 | 0.0281905 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0272914 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0270991 |
| NEBL | nebulette | 0.0270045 |
| IRS2 | insulin receptor substrate 2 | 0.0265014 |
| DNAH5 | dynein, axonemal, heavy chain 5 | 0.02638 |
| PLEKHA7 | pleckstrin homology domain containing, family A member 7 | 0.0263548 |
| USP3 | ubiquitin specific peptidase 3 | 0.0262609 |
| VIM | vimentin | 0.0262309 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0260887 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0260256 |
| PLS3 | plastin 3 | 0.0257693 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.0253608 |
| KRT7 | keratin 7, type II | 0.0247198 |
| PRKCA | protein kinase C, alpha | 0.0246744 |
| TMEM164 | transmembrane protein 164 | 0.0245484 |
| TOP1 | topoisomerase (DNA) I | 0.0245349 |
| KRT18 | keratin 18, type I | 0.0243975 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0243335 |
| NNMT | nicotinamide N-methyltransferase | 0.0243237 |
| FOXP1 | forkhead box P1 | 0.0242414 |
| ANXA1 | annexin A1 | 0.024061 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0240179 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0239949 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0239654 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0238956 |
| ZFHX3 | zinc finger homeobox 3 | 0.0238126 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0237035 |
| ABLIM2 | actin binding LIM protein family, member 2 | 0.02367 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE10A | phosphodiesterase 10A | -0.237742 |
| SMAD3 | SMAD family member 3 | -0.127627 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.115239 |
| GRB10 | growth factor receptor-bound protein 10 | -0.114051 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.10554 |
| EXT1 | exostosin glycosyltransferase 1 | -0.101154 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0988444 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | -0.0845811 |
| CMIP | c-Maf inducing protein | -0.0845554 |
| MT2A | metallothionein 2A | -0.0844844 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0825121 |
| STC1 | stanniocalcin 1 | -0.0804263 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0790588 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0743043 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0735812 |
| NAV2 | neuron navigator 2 | -0.0724465 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0724171 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0719168 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0716199 |
| RNF213 | ring finger protein 213 | -0.0690697 |
| OSMR | oncostatin M receptor | -0.0690673 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.066787 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0632112 |
| RPS19 | ribosomal protein S19 | -0.0631737 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.061165 |
| RIGI | RNA sensor RIG-I | -0.0600335 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0595427 |
| FAM107B | family with sequence similarity 107, member B | -0.058808 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0564426 |
| MYO10 | myosin X | -0.0557413 |
| CD44 | CD44 molecule (Indian blood group) | -0.0554316 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0535614 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0535123 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0526019 |
| RIN2 | Ras and Rab interactor 2 | -0.0525398 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0516789 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0508329 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0495809 |
| KIAA1217 | KIAA1217 | -0.0487648 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0480363 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0464617 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.045472 |
| RAI14 | retinoic acid induced 14 | -0.0441741 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0439849 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0439661 |
| PLSCR1 | phospholipid scramblase 1 | -0.043575 |
| GOLGA4 | golgin A4 | -0.0430059 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0422658 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0409176 |
| RSPO3 | R-spondin 3 | -0.0408105 |
| RASA2 | RAS p21 protein activator 2 | -0.0405494 |
| PARD3 | par-3 family cell polarity regulator | -0.040315 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0399094 |
| CA12 | carbonic anhydrase XII | -0.0391931 |
| EGFR | epidermal growth factor receptor | -0.0382815 |
| DUSP16 | dual specificity phosphatase 16 | -0.0382629 |
| ETNK1 | ethanolamine kinase 1 | -0.0381386 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0379273 |
| SP100 | SP100 nuclear antigen | -0.0377839 |
| LOXL2 | lysyl oxidase-like 2 | -0.0377556 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0375854 |
| TDRD7 | tudor domain containing 7 | -0.0369311 |
| GPRIN3 | GPRIN family member 3 | -0.0368868 |
| KYNU | kynureninase | -0.0364907 |
| RUNX1 | runt-related transcription factor 1 | -0.0361311 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0351208 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0340834 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0331524 |
| TXNRD1 | thioredoxin reductase 1 | -0.0329362 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0327128 |
| RPLP1 | ribosomal protein, large, P1 | -0.032303 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0321283 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0318982 |
| NDRG1 | N-myc downstream regulated 1 | -0.0317824 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0317421 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0316556 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0312399 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0310151 |
| PDZD8 | PDZ domain containing 8 | -0.0307025 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0302916 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0302615 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0299319 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.0298428 |
| RRBP1 | ribosome binding protein 1 | -0.0293627 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0293581 |
| TPM1 | tropomyosin 1 (alpha) | -0.029256 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0292148 |
| ATG7 | autophagy related 7 | -0.0290942 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0289141 |
| GRAMD1B | GRAM domain containing 1B | -0.0288247 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.028502 |
| GOLGB1 | golgin B1 | -0.0284 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.028203 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0281658 |
| AXL | AXL receptor tyrosine kinase | -0.0279496 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0279224 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0277618 |
| LAMC2 | laminin, gamma 2 | -0.0277116 |
| JMJD1C | jumonji domain containing 1C | -0.0276785 |
| ARHGAP42 | Rho GTPase activating protein 42 | -0.0275633 |
