| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clobetasol propionate perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clobetasol propionate_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MEST | mesoderm specific transcript | 0.663699 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0820521 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.05704 |
| MEOX2 | mesenchyme homeobox 2 | 0.0455101 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.043119 |
| CALR | calreticulin | 0.0410555 |
| RANBP17 | RAN binding protein 17 | 0.0404643 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0385798 |
| RNF145 | ring finger protein 145 | 0.0374696 |
| MKI67 | marker of proliferation Ki-67 | 0.0371668 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0371537 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0367496 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0361224 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0342814 |
| EGFR | epidermal growth factor receptor | 0.0340596 |
| MATR3 | matrin 3 | 0.0337081 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.03328 |
| RBM39 | RNA binding motif protein 39 | 0.0326337 |
| HOXA3 | homeobox A3 | 0.0318969 |
| BOC | BOC cell adhesion associated, oncogene regulated | 0.0308915 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0296528 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0290056 |
| UTRN | utrophin | 0.0285028 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0276674 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0274323 |
| PCBP2 | poly(rC) binding protein 2 | 0.0272824 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0252774 |
| RAD51B | RAD51 paralog B | 0.0247096 |
| PCDH7 | protocadherin 7 | 0.0245867 |
| XPO1 | exportin 1 | 0.0245369 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0242076 |
| ZNF292 | zinc finger protein 292 | 0.0241535 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0240749 |
| OGA | O-GlcNAcase | 0.0240103 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0239084 |
| DIAPH3 | diaphanous-related formin 3 | 0.0238012 |
| GOLM2 | golgi membrane protein 2 | 0.0236102 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0232353 |
| FAM120B | family with sequence similarity 120B | 0.0228734 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0227902 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.0227186 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0225935 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0223826 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0223574 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0223537 |
| YBX1 | Y box binding protein 1 | 0.0218876 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0217803 |
| GSE1 | Gse1 coiled-coil protein | 0.0217642 |
| CBX5 | chromobox homolog 5 | 0.0216027 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0215889 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0214108 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.021287 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0212215 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0211975 |
| PTEN | phosphatase and tensin homolog | 0.0211291 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0206985 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0206698 |
| PTK2 | protein tyrosine kinase 2 | 0.0206537 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0204685 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0204472 |
| TCERG1 | transcription elongation regulator 1 | 0.0203108 |
| SUCO | SUN domain containing ossification factor | 0.0202592 |
| ZNF608 | zinc finger protein 608 | 0.0202427 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0201843 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | 0.0199672 |
| ITGAV | integrin, alpha V | 0.0198996 |
| VWA8 | von Willebrand factor A domain containing 8 | 0.0197596 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.019729 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.019709 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0197001 |
| KIF11 | kinesin family member 11 | 0.0196763 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0195873 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0194576 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0193931 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0193648 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0193177 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0191667 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0190992 |
| ZNF148 | zinc finger protein 148 | 0.0189721 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0188722 |
| TBC1D12 | TBC1 domain family, member 12 | 0.0188531 |
| NCKAP1 | NCK-associated protein 1 | 0.0188015 |
| TXNRD1 | thioredoxin reductase 1 | 0.018764 |
| SON | SON DNA binding protein | 0.0186273 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0185284 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0184131 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0180505 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0180485 |
| UBE3A | ubiquitin protein ligase E3A | 0.0180056 |
| CD2AP | CD2-associated protein | 0.0179727 |
| SCAF4 | SR-related CTD-associated factor 4 | 0.0178676 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.0176994 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0176899 |
| RYBP | RING1 and YY1 binding protein | 0.0174206 |
| APP | amyloid beta (A4) precursor protein | 0.017405 |
| CEP192 | centrosomal protein 192kDa | 0.0173352 |
| WDR43 | WD repeat domain 43 | 0.0172731 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0172674 |
| DMXL1 | Dmx-like 1 | 0.0172287 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.0171508 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.199739 |
| VIM | vimentin | -0.115445 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.100056 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0956594 |
| CADM2 | cell adhesion molecule 2 | -0.0913576 |
| MGP | matrix Gla protein | -0.0904734 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0892922 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0837312 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0702077 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0639838 |
| FNDC3B | fibronectin type III domain containing 3B | -0.060895 |
| IER3 | immediate early response 3 | -0.0599771 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0582294 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0558882 |
| ACTG1 | actin gamma 1 | -0.0547861 |
| PTMA | prothymosin, alpha | -0.0534644 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0498559 |
| MYOF | myoferlin | -0.0474145 |
| TMSB10 | thymosin beta 10 | -0.0441187 |
| HMGA2 | high mobility group AT-hook 2 | -0.0433255 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0432294 |
| MAP1B | microtubule-associated protein 1B | -0.043027 |
| RPS24 | ribosomal protein S24 | -0.0429306 |
| ZFHX3 | zinc finger homeobox 3 | -0.0418493 |
| RPL34 | ribosomal protein L34 | -0.0411686 |
| RPLP1 | ribosomal protein, large, P1 | -0.0380365 |
| ENO1 | enolase 1, (alpha) | -0.0369132 |
| SEPTIN11 | septin 11 | -0.0368941 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0357458 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0342922 |
| ANO6 | anoctamin 6 | -0.0341401 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0333942 |
| RPS8 | ribosomal protein S8 | -0.033148 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0329638 |
| TET1 | tet methylcytosine dioxygenase 1 | -0.0323557 |
| LDHA | lactate dehydrogenase A | -0.0317171 |
| FLNB | filamin B, beta | -0.0317042 |
| MICU1 | mitochondrial calcium uptake 1 | -0.0298256 |
| RSU1 | Ras suppressor protein 1 | -0.0297777 |
| HMGA1 | high mobility group AT-hook 1 | -0.028995 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0289588 |
| RPLP2 | ribosomal protein, large, P2 | -0.0288244 |
| TUBB | tubulin, beta class I | -0.0286924 |
| CUX1 | cut-like homeobox 1 | -0.0284233 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0284001 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0283215 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0281268 |
| RACK1 | receptor for activated C kinase 1 | -0.0275173 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0271252 |
| RPL19 | ribosomal protein L19 | -0.0268466 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0264776 |
| RAI1 | retinoic acid induced 1 | -0.0264063 |
| JMJD1C | jumonji domain containing 1C | -0.026327 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0262301 |
| NDRG1 | N-myc downstream regulated 1 | -0.0260327 |
| RPL28 | ribosomal protein L28 | -0.0257861 |
| TULP4 | tubby like protein 4 | -0.0257228 |
| PKM | pyruvate kinase, muscle | -0.0257026 |
| RPL35A | ribosomal protein L35a | -0.0256927 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0245762 |
| BCOR | BCL6 corepressor | -0.0243736 |
| PLS3 | plastin 3 | -0.0241962 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0238409 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0236084 |
| RPS25 | ribosomal protein S25 | -0.0229285 |
| CDK6 | cyclin-dependent kinase 6 | -0.0228829 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0228079 |
| RPL30 | ribosomal protein L30 | -0.0222239 |
| FRMD6 | FERM domain containing 6 | -0.0221612 |
| RPL37 | ribosomal protein L37 | -0.0221578 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0219981 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0219051 |
| RPS23 | ribosomal protein S23 | -0.0218246 |
| FOXC1 | forkhead box C1 | -0.0216747 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0216086 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0216014 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0214185 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0213077 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | -0.0212692 |
| LOXL2 | lysyl oxidase-like 2 | -0.0211079 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.021072 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.020686 |
| RPS6 | ribosomal protein S6 | -0.0206777 |
| RPS13 | ribosomal protein S13 | -0.0206446 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0205762 |
| RPS19 | ribosomal protein S19 | -0.0205739 |
| RPS2 | ribosomal protein S2 | -0.0204423 |
| RPS11 | ribosomal protein S11 | -0.0204168 |
| TPI1 | triosephosphate isomerase 1 | -0.020231 |
| RPL31 | ribosomal protein L31 | -0.0201839 |
| RPL7A | ribosomal protein L7a | -0.0195784 |
| TPM4 | tropomyosin 4 | -0.01937 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0189977 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0189791 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0188524 |
| RPS27A | ribosomal protein S27a | -0.0187137 |
| RPS3 | ribosomal protein S3 | -0.0186715 |
| CREM | cAMP responsive element modulator | -0.0186461 |
| TRIM9 | tripartite motif containing 9 | -0.0184883 |
| NHSL1 | NHS-like 1 | -0.0182093 |
