| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clobetasol propionate perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clobetasol propionate_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.288133 |
| AHNAK | AHNAK nucleoprotein | 0.188863 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.160492 |
| FKBP5 | FK506 binding protein 5 | 0.138684 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.129954 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.101757 |
| HMGA2 | high mobility group AT-hook 2 | 0.0945331 |
| TXNIP | thioredoxin interacting protein | 0.0903225 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0883158 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0848818 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0813321 |
| TOP1 | topoisomerase (DNA) I | 0.0795289 |
| PON2 | paraoxonase 2 | 0.0726205 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0583011 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0563478 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0555473 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0513432 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0510916 |
| CAPRIN2 | caprin family member 2 | 0.0507333 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0494958 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0488427 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | 0.0475112 |
| PLEC | plectin | 0.0444225 |
| MUC17 | mucin 17, cell surface associated | 0.0444153 |
| POTEF | POTE ankyrin domain family, member F | 0.0430907 |
| BCL2L1 | BCL2-like 1 | 0.0430593 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0429742 |
| LAMA4 | laminin, alpha 4 | 0.0403387 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | 0.0402471 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0373368 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0373167 |
| ABLIM2 | actin binding LIM protein family, member 2 | 0.036133 |
| YAP1 | Yes-associated protein 1 | 0.034872 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0344411 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0338096 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0335133 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.033296 |
| RASAL2 | RAS protein activator like 2 | 0.0331621 |
| LDLRAD3 | low density lipoprotein receptor class A domain containing 3 | 0.0330532 |
| MOSMO | modulator of smoothened | 0.0328733 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0327738 |
| MT2A | metallothionein 2A | 0.0323645 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0322481 |
| ATAD2B | ATPase family, AAA domain containing 2B | 0.0305431 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.030347 |
| EFNA5 | ephrin-A5 | 0.0301191 |
| KIAA0232 | KIAA0232 | 0.0297454 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0296077 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0291401 |
| TMEM164 | transmembrane protein 164 | 0.0289732 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0285037 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.028006 |
| NPSR1 | neuropeptide S receptor 1 | 0.0275041 |
| IL6ST | interleukin 6 signal transducer | 0.0272733 |
| FMNL2 | formin-like 2 | 0.0271144 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0270376 |
| RTN4 | reticulon 4 | 0.0261831 |
| SLC22A3 | solute carrier family 22 (organic cation transporter), member 3 | 0.026055 |
| MT1X | metallothionein 1X | 0.0255793 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0253266 |
| CCDC6 | coiled-coil domain containing 6 | 0.0250064 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0249753 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0237353 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0235948 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.023365 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0232279 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0229806 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0227466 |
| EHBP1 | EH domain binding protein 1 | 0.0226886 |
| TGM2 | transglutaminase 2 | 0.0226166 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.022513 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0222808 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0220048 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.022003 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0219301 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.0218519 |
| CLIC4 | chloride intracellular channel 4 | 0.0218273 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0212579 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.0212084 |
| TAOK3 | TAO kinase 3 | 0.0212006 |
| RAB10 | RAB10, member RAS oncogene family | 0.0211984 |
| CORO1C | coronin, actin binding protein, 1C | 0.0211144 |
| PTK2 | protein tyrosine kinase 2 | 0.020732 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0204964 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0202099 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0201888 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0199544 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0199452 |
| SIK3 | SIK family kinase 3 | 0.0196151 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0196126 |
| CCDC88A | coiled-coil domain containing 88A | 0.0195984 |
| TJP2 | tight junction protein 2 | 0.0195437 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.0192585 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0188998 |
| WWC1 | WW and C2 domain containing 1 | 0.0188596 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0188457 |
| OSMR | oncostatin M receptor | 0.0187462 |
| CHKA | choline kinase alpha | 0.0186684 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0183707 |
| EREG | epiregulin | 0.0182612 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.213781 |
| TMSB10 | thymosin beta 10 | -0.161296 |
| LAMB3 | laminin, beta 3 | -0.158346 |
| NDRG1 | N-myc downstream regulated 1 | -0.140026 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.134116 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.130687 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.101916 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0980157 |
| PTMA | prothymosin, alpha | -0.0973301 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0892525 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0823502 |
| FLNB | filamin B, beta | -0.076672 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0764735 |
| FAM107B | family with sequence similarity 107, member B | -0.0757301 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0664527 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.066175 |
| HMGA1 | high mobility group AT-hook 1 | -0.0642543 |
| ASPH | aspartate beta-hydroxylase | -0.063647 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0635242 |
| LAMC2 | laminin, gamma 2 | -0.0620336 |
| B2M | beta-2-microglobulin | -0.0619376 |
| LMO7 | LIM domain 7 | -0.0612176 |
| VIM | vimentin | -0.0602469 |
| MXD1 | MAX dimerization protein 1 | -0.0600853 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0584749 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.056484 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0563691 |
| PRSS3 | protease, serine, 3 | -0.0536946 |
| ARHGAP42 | Rho GTPase activating protein 42 | -0.0513152 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0509399 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0503921 |
| PARD3 | par-3 family cell polarity regulator | -0.05017 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.050104 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0480708 |
| SLC35F3 | solute carrier family 35, member F3 | -0.047796 |
| FTL | ferritin, light polypeptide | -0.0475289 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0466032 |
| VCAN | versican | -0.0451811 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0446464 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0438945 |
| RPL37A | ribosomal protein L37a | -0.043516 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0426848 |
| SLMAP | sarcolemma associated protein | -0.0407149 |
| KLK10 | kallikrein-related peptidase 10 | -0.0400739 |
| S100A10 | S100 calcium binding protein A10 | -0.0392638 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0391206 |
| RPS3 | ribosomal protein S3 | -0.0388252 |
| RPS2 | ribosomal protein S2 | -0.0383903 |
| FAM3C | family with sequence similarity 3, member C | -0.0383131 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0381038 |
| RPLP1 | ribosomal protein, large, P1 | -0.0380607 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0379248 |
| RPL12 | ribosomal protein L12 | -0.0379181 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0378911 |
| RPS8 | ribosomal protein S8 | -0.0376663 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0369253 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.03625 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0360503 |
| ACTG1 | actin gamma 1 | -0.0354525 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0352814 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0351793 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0345453 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.034464 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0343797 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0343184 |
| SMAD3 | SMAD family member 3 | -0.0343134 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0338976 |
| RPL35A | ribosomal protein L35a | -0.0332776 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0324011 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0322873 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0322247 |
| RPL31 | ribosomal protein L31 | -0.03206 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0320016 |
| STK39 | serine threonine kinase 39 | -0.0318846 |
| FA2H | fatty acid 2-hydroxylase | -0.0313034 |
| SQSTM1 | sequestosome 1 | -0.0311997 |
| RPS27A | ribosomal protein S27a | -0.0310926 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0305772 |
| RPL34 | ribosomal protein L34 | -0.0302204 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0301383 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0299706 |
| TXNRD1 | thioredoxin reductase 1 | -0.0299157 |
| RPS21 | ribosomal protein S21 | -0.0297106 |
| DSG2 | desmoglein 2 | -0.02961 |
| DIAPH2 | diaphanous-related formin 2 | -0.0295125 |
| JMJD1C | jumonji domain containing 1C | -0.0293982 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0290522 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.028928 |
| GNAS | GNAS complex locus | -0.0286669 |
| PLAUR | plasminogen activator, urokinase receptor | -0.028651 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0285268 |
| EZR | ezrin | -0.028363 |
| RPL11 | ribosomal protein L11 | -0.0283612 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0280269 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.027953 |
| RPS12 | ribosomal protein S12 | -0.0277823 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0276956 |
| RPS6 | ribosomal protein S6 | -0.0275881 |
| RPS27 | ribosomal protein S27 | -0.0271708 |
| S100A6 | S100 calcium binding protein A6 | -0.0271147 |
