| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clobetasol propionate perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clobetasol propionate_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NRCAM | neuronal cell adhesion molecule | 0.113815 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.111983 |
| CD109 | CD109 molecule | 0.105549 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.1005 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0933303 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.088187 |
| FKBP5 | FK506 binding protein 5 | 0.0800087 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0759023 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0746485 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0719254 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0695615 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0618886 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0609687 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0576755 |
| NBAS | neuroblastoma amplified sequence | 0.0572525 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0557231 |
| ANXA2 | annexin A2 | 0.0549484 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0546027 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0545128 |
| DSCAM | Down syndrome cell adhesion molecule | 0.052196 |
| IL6ST | interleukin 6 signal transducer | 0.0493954 |
| COPA | coatomer protein complex, subunit alpha | 0.0491296 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0485542 |
| MEF2A | myocyte enhancer factor 2A | 0.0465468 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0444041 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0443211 |
| PDE10A | phosphodiesterase 10A | 0.044158 |
| CDC73 | cell division cycle 73 | 0.0434022 |
| HELZ | helicase with zinc finger | 0.043368 |
| TMEM178B | transmembrane protein 178B | 0.0414374 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.03906 |
| SRPK2 | SRSF protein kinase 2 | 0.0390419 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0378584 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0371783 |
| RYBP | RING1 and YY1 binding protein | 0.0365958 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.036234 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0358915 |
| EMP1 | epithelial membrane protein 1 | 0.0358593 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0355014 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0354245 |
| CALU | calumenin | 0.0351033 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0350353 |
| USP53 | ubiquitin specific peptidase 53 | 0.0343136 |
| RHEB | Ras homolog enriched in brain | 0.0341838 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 0.0339688 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0338034 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0338022 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0336873 |
| AFDN | afadin, adherens junction formation factor | 0.032909 |
| STRIP2 | striatin interacting protein 2 | 0.0328863 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0323191 |
| SPAG9 | sperm associated antigen 9 | 0.0321205 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0320251 |
| PHF21A | PHD finger protein 21A | 0.0320191 |
| PTK2 | protein tyrosine kinase 2 | 0.0319814 |
| RLF | rearranged L-myc fusion | 0.0315571 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0312774 |
| RNF145 | ring finger protein 145 | 0.0305497 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0301904 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0300834 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0300655 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0300176 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0289048 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0288097 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0287956 |
| GPATCH2L | G patch domain containing 2-like | 0.0284508 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0283326 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.028154 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0278996 |
| CDK6 | cyclin-dependent kinase 6 | 0.0278545 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0276217 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0274114 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0270472 |
| XPO1 | exportin 1 | 0.026971 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0269417 |
| HMGA2 | high mobility group AT-hook 2 | 0.0266834 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 | 0.0264021 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0257586 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0257513 |
| IRS2 | insulin receptor substrate 2 | 0.0257079 |
| NUP58 | nucleoporin 58 | 0.0255365 |
| SAMTOR | S-adenosylmethionine sensor upstream of mTORC1 | 0.0247967 |
| TFG | TRK-fused gene | 0.02451 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0244838 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0243992 |
| TAC4 | tachykinin 4 (hemokinin) | 0.024201 |
| CALR | calreticulin | 0.0241471 |
| CUL1 | cullin 1 | 0.0240244 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0239966 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0238458 |
| WDR43 | WD repeat domain 43 | 0.0237458 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0236395 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0236182 |
| BBS2 | Bardet-Biedl syndrome 2 | 0.0234605 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0233154 |
| ZNF292 | zinc finger protein 292 | 0.0232632 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0232449 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0231384 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0230212 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0229079 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.270197 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.258785 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.170994 |
| FRMD4A | FERM domain containing 4A | -0.141621 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.137549 |
| GPC6 | glypican 6 | -0.110547 |
| MT2A | metallothionein 2A | -0.108667 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.107976 |
| VIM | vimentin | -0.10091 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0975979 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0964336 |
| TMSB10 | thymosin beta 10 | -0.0810546 |
| MACROD2 | MACRO domain containing 2 | -0.074515 |
| TNNC1 | troponin C type 1 (slow) | -0.0685532 |
| HLA-B | major histocompatibility complex, class I, B | -0.0657051 |
| FMN1 | formin 1 | -0.0615049 |
| EHBP1 | EH domain binding protein 1 | -0.0614615 |
| NLGN1 | neuroligin 1 | -0.057732 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0576514 |
| RUNX1 | runt-related transcription factor 1 | -0.0549613 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0529033 |
| ACTG1 | actin gamma 1 | -0.052569 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0515581 |
| OXR1 | oxidation resistance 1 | -0.0514453 |
| VGF | VGF nerve growth factor inducible | -0.0511109 |
| SCFD2 | sec1 family domain containing 2 | -0.0505625 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0502383 |
| MITF | microphthalmia-associated transcription factor | -0.0494709 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0491923 |
| EGR1 | early growth response 1 | -0.048505 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0433536 |
| ENO1 | enolase 1, (alpha) | -0.0426008 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0423476 |
| MYO10 | myosin X | -0.0414995 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.0409755 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0404989 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0399658 |
| PRELID2 | PRELI domain containing 2 | -0.0392105 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0388192 |
| DCT | dopachrome tautomerase | -0.0387405 |
| PRKD1 | protein kinase D1 | -0.0376743 |
| FMNL2 | formin-like 2 | -0.0373443 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0361409 |
| RAD51B | RAD51 paralog B | -0.0360563 |
| CENPF | centromere protein F, 350/400kDa | -0.0357595 |
| SDC2 | syndecan 2 | -0.0354319 |
| B2M | beta-2-microglobulin | -0.0351794 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.0351248 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0330992 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0330726 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0316305 |
| S100A6 | S100 calcium binding protein A6 | -0.0313616 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0313538 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0312042 |
| RPS19 | ribosomal protein S19 | -0.030656 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0301777 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0301588 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0301498 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0296338 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0291414 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0285263 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0281008 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0279224 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0277123 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.027371 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0269004 |
| NDRG1 | N-myc downstream regulated 1 | -0.0268435 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0265295 |
| FRMD6 | FERM domain containing 6 | -0.0262607 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0259721 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.025857 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0256803 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0253544 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.025238 |
| ZSWIM5 | zinc finger, SWIM-type containing 5 | -0.0248359 |
| PI15 | peptidase inhibitor 15 | -0.0247896 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0246931 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0245661 |
| TPI1 | triosephosphate isomerase 1 | -0.0243792 |
| ZNF704 | zinc finger protein 704 | -0.0242308 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | -0.0241892 |
| S100A9 | S100 calcium binding protein A9 | -0.0241444 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0241428 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0240142 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0240069 |
| FTL | ferritin, light polypeptide | -0.0238602 |
| RPL36 | ribosomal protein L36 | -0.0235879 |
| SBF2 | SET binding factor 2 | -0.0235241 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0234075 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0233327 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0233274 |
| PTMA | prothymosin, alpha | -0.0233223 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.023252 |
| VCL | vinculin | -0.0231842 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0230638 |
| RNF213 | ring finger protein 213 | -0.0229121 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0226087 |
| IER3 | immediate early response 3 | -0.0226036 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0221734 |
| NBEA | neurobeachin | -0.0217226 |
