| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clobetasol propionate perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clobetasol propionate_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.145232 |
| EFNA5 | ephrin-A5 | 0.130726 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.102809 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.101769 |
| AHNAK | AHNAK nucleoprotein | 0.0871312 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0817985 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0756837 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0740881 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0715965 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0668079 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.066079 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0613069 |
| BICC1 | BicC family RNA binding protein 1 | 0.0580992 |
| FKBP5 | FK506 binding protein 5 | 0.0555616 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0530942 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0527883 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0526981 |
| FAT1 | FAT atypical cadherin 1 | 0.0518678 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0506434 |
| NRG1 | neuregulin 1 | 0.0496956 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0491003 |
| RASAL2 | RAS protein activator like 2 | 0.0489268 |
| LMO7 | LIM domain 7 | 0.0473242 |
| PHF3 | PHD finger protein 3 | 0.0464657 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.045059 |
| SPAG9 | sperm associated antigen 9 | 0.044858 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0444941 |
| EHBP1 | EH domain binding protein 1 | 0.0441497 |
| APP | amyloid beta (A4) precursor protein | 0.0437218 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0437004 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0430627 |
| LOX | lysyl oxidase | 0.0421003 |
| CCNY | cyclin Y | 0.0419987 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.041344 |
| HOMER2 | homer scaffolding protein 2 | 0.0407772 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0405559 |
| TOP1 | topoisomerase (DNA) I | 0.0404771 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.03897 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0387471 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0386269 |
| FLNB | filamin B, beta | 0.0385042 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0384696 |
| RBM39 | RNA binding motif protein 39 | 0.038148 |
| BCL2L1 | BCL2-like 1 | 0.0376922 |
| CLTC | clathrin, heavy chain (Hc) | 0.0375314 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0373044 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0371048 |
| TJP1 | tight junction protein 1 | 0.0370851 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0370157 |
| KIF13B | kinesin family member 13B | 0.036922 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0359634 |
| RAD51B | RAD51 paralog B | 0.0355208 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0354968 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0344144 |
| MCU | mitochondrial calcium uniporter | 0.0344137 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0342968 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0341968 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.034029 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.033741 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0336429 |
| RCOR1 | REST corepressor 1 | 0.0334922 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0334421 |
| DPYD | dihydropyrimidine dehydrogenase | 0.033277 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0328034 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0321746 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0321729 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0321709 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0317796 |
| HELZ | helicase with zinc finger | 0.0314248 |
| FNDC3B | fibronectin type III domain containing 3B | 0.030767 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0306777 |
| RPRD1B | regulation of nuclear pre-mRNA domain containing 1B | 0.0303531 |
| YAP1 | Yes-associated protein 1 | 0.0301577 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0300352 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0299448 |
| PRKCA | protein kinase C, alpha | 0.0297207 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0296882 |
| ERBIN | erbb2 interacting protein | 0.0295192 |
| MYO9A | myosin IXA | 0.0293851 |
| PYGB | phosphorylase, glycogen; brain | 0.0293275 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0288899 |
| GOLGB1 | golgin B1 | 0.0288215 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0286891 |
| FNIP1 | folliculin interacting protein 1 | 0.0285634 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0284914 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0284767 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0279898 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0278226 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0274616 |
| CLIC4 | chloride intracellular channel 4 | 0.0272954 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0272046 |
| CEP70 | centrosomal protein 70kDa | 0.0271899 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0270628 |
| COPA | coatomer protein complex, subunit alpha | 0.0270372 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0270262 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.026937 |
| SHROOM3 | shroom family member 3 | 0.0269007 |
| EGFR | epidermal growth factor receptor | 0.0268627 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0267892 |
| SCFD1 | sec1 family domain containing 1 | 0.0266625 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.206161 |
| PTMA | prothymosin, alpha | -0.161104 |
| TMSB10 | thymosin beta 10 | -0.137062 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.126779 |
| MT2A | metallothionein 2A | -0.103321 |
| NDRG1 | N-myc downstream regulated 1 | -0.0942603 |
| FTL | ferritin, light polypeptide | -0.0904156 |
| HLA-B | major histocompatibility complex, class I, B | -0.0886126 |
| B2M | beta-2-microglobulin | -0.0830254 |
| RPLP1 | ribosomal protein, large, P1 | -0.0755676 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0735889 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0724325 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0718111 |
| PLAU | plasminogen activator, urokinase | -0.0690524 |
| HMGA1 | high mobility group AT-hook 1 | -0.0651531 |
| KRT19 | keratin 19, type I | -0.0637875 |
| RPS8 | ribosomal protein S8 | -0.059798 |
| RPL23 | ribosomal protein L23 | -0.0595342 |
| RPL35A | ribosomal protein L35a | -0.0585415 |
| VIM | vimentin | -0.0580428 |
| RPL19 | ribosomal protein L19 | -0.0565484 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0560266 |
| ACTG1 | actin gamma 1 | -0.0513155 |
| RPS6 | ribosomal protein S6 | -0.0495731 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0487292 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0482284 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0462221 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0459736 |
| MT1X | metallothionein 1X | -0.0458528 |
| RPS19 | ribosomal protein S19 | -0.0455266 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0450436 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0443246 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0427841 |
| TMSB4X | thymosin beta 4, X-linked | -0.0415252 |
| IER3 | immediate early response 3 | -0.0412032 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0407556 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0397507 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0396934 |
| RPS29 | ribosomal protein S29 | -0.0393713 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0392412 |
| LCN2 | lipocalin 2 | -0.0366638 |
| RPS23 | ribosomal protein S23 | -0.0349638 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.034663 |
| RPS21 | ribosomal protein S21 | -0.0338745 |
| RPLP0 | ribosomal protein, large, P0 | -0.0337691 |
| RPS27A | ribosomal protein S27a | -0.0337544 |
| RPL34 | ribosomal protein L34 | -0.0332102 |
| CSTB | cystatin B (stefin B) | -0.0331684 |
| RPL9 | ribosomal protein L9 | -0.0331586 |
| S100A6 | S100 calcium binding protein A6 | -0.0330741 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0330682 |
| RPS24 | ribosomal protein S24 | -0.0327366 |
| RPS3 | ribosomal protein S3 | -0.0326963 |
| APOL1 | apolipoprotein L, 1 | -0.0322937 |
| RPL37A | ribosomal protein L37a | -0.0322855 |
| RPL11 | ribosomal protein L11 | -0.0322635 |
| RACK1 | receptor for activated C kinase 1 | -0.0319662 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0317708 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.031758 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0315914 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0315404 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0313435 |
| POTEF | POTE ankyrin domain family, member F | -0.0310451 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0309282 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.030823 |
| RPL31 | ribosomal protein L31 | -0.0298796 |
| FAM162A | family with sequence similarity 162, member A | -0.0290777 |
| CD47 | CD47 molecule | -0.0290538 |
| SMAD3 | SMAD family member 3 | -0.0289979 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0289842 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0289836 |
| CDCP1 | CUB domain containing protein 1 | -0.0287862 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0287679 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0286006 |
| RPS14 | ribosomal protein S14 | -0.0285164 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0284844 |
| RPS25 | ribosomal protein S25 | -0.0282762 |
| RPLP2 | ribosomal protein, large, P2 | -0.0280514 |
| RPS27 | ribosomal protein S27 | -0.0280087 |
| LAMC2 | laminin, gamma 2 | -0.027354 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0271688 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0260813 |
| MMP7 | matrix metallopeptidase 7 | -0.0260193 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.025315 |
| RPL28 | ribosomal protein L28 | -0.0251608 |
| KIAA1217 | KIAA1217 | -0.0249989 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0249056 |
| RPL5 | ribosomal protein L5 | -0.0248619 |
| S100A10 | S100 calcium binding protein A10 | -0.0241166 |
| CD44 | CD44 molecule (Indian blood group) | -0.0239018 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0237668 |
| RPS12 | ribosomal protein S12 | -0.0235085 |
| HLA-E | major histocompatibility complex, class I, E | -0.0233483 |
| ENO1 | enolase 1, (alpha) | -0.0231631 |
| HLA-A | major histocompatibility complex, class I, A | -0.0231627 |
| FOSL1 | FOS-like antigen 1 | -0.0231496 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0230747 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0229309 |
| PKM | pyruvate kinase, muscle | -0.0229036 |
| MX2 | MX dynamin-like GTPase 2 | -0.022717 |
