| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clobetasol propionate perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clobetasol propionate_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | 0.152417 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.146106 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0627036 |
| DPH6 | diphthamine biosynthesis 6 | 0.0621059 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0598363 |
| MSI2 | musashi RNA-binding protein 2 | 0.0547945 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0537546 |
| TOP1 | topoisomerase (DNA) I | 0.0537253 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.050527 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0489384 |
| FKBP5 | FK506 binding protein 5 | 0.0482986 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0455407 |
| PLAT | plasminogen activator, tissue | 0.0450571 |
| KCNIP4 | Kv channel interacting protein 4 | 0.0449363 |
| HMGA2 | high mobility group AT-hook 2 | 0.0420505 |
| FMN1 | formin 1 | 0.041061 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.040694 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0406269 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0406144 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0393877 |
| SEPTIN9 | septin 9 | 0.0392196 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0384005 |
| CDH13 | cadherin 13 | 0.0378738 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0376003 |
| DNMBP | dynamin binding protein | 0.0356503 |
| NAV2 | neuron navigator 2 | 0.0352166 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.034839 |
| ATXN1 | ataxin 1 | 0.0344605 |
| CADM2 | cell adhesion molecule 2 | 0.0338973 |
| TENM4 | teneurin transmembrane protein 4 | 0.0328932 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0323665 |
| PCBP2 | poly(rC) binding protein 2 | 0.032045 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0315117 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.0314032 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0310874 |
| KLF9 | Kruppel-like factor 9 | 0.0310435 |
| UNC5C | unc-5 homolog C (C. elegans) | 0.0308134 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0307254 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0305396 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0285385 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0282018 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0280969 |
| SMAD3 | SMAD family member 3 | 0.027944 |
| MCL1 | myeloid cell leukemia 1 | 0.0276838 |
| ITGA1 | integrin, alpha 1 | 0.0267724 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0265557 |
| RUNX2 | runt-related transcription factor 2 | 0.026531 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0254905 |
| KCTD3 | potassium channel tetramerization domain containing 3 | 0.025178 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.0246101 |
| EXOC4 | exocyst complex component 4 | 0.0244248 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0239093 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | 0.0238481 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.023335 |
| SMAD6 | SMAD family member 6 | 0.0232374 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0229106 |
| TCF12 | transcription factor 12 | 0.0227462 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0225877 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0224815 |
| CCND3 | cyclin D3 | 0.0224407 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.022198 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0220569 |
| PCBP3 | poly(rC) binding protein 3 | 0.0218946 |
| INTS6 | integrator complex subunit 6 | 0.0214548 |
| UNC5B | unc-5 homolog B (C. elegans) | 0.0213839 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0212375 |
| ATRNL1 | attractin-like 1 | 0.0210822 |
| ENAH | enabled homolog (Drosophila) | 0.0204149 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0203601 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0200447 |
| CSNK1D | casein kinase 1, delta | 0.0199616 |
| SMYD3 | SET and MYND domain containing 3 | 0.0198767 |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.0196734 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0196293 |
| DGKH | diacylglycerol kinase, eta | 0.0196199 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0195444 |
| HIP1 | huntingtin interacting protein 1 | 0.019464 |
| RHOA | ras homolog family member A | 0.0194141 |
| FNIP1 | folliculin interacting protein 1 | 0.0194028 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0192908 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0192284 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.019167 |
| RBM20 | RNA binding motif protein 20 | 0.0191577 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0191517 |
| GSPT1 | G1 to S phase transition 1 | 0.0190215 |
| VMP1 | vacuole membrane protein 1 | 0.0189518 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0188936 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0188678 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0188491 |
| SECISBP2L | SECIS binding protein 2-like | 0.0188398 |
| NBAS | neuroblastoma amplified sequence | 0.0188109 |
| CCNH | cyclin H | 0.0186801 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0186703 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0185214 |
| ATXN10 | ataxin 10 | 0.0183533 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0182196 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | 0.0179564 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0177099 |
| ERBIN | erbb2 interacting protein | 0.0176759 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.017643 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.253283 |
| IGF2 | insulin-like growth factor 2 | -0.243071 |
| PTMA | prothymosin, alpha | -0.124575 |
| COL1A1 | collagen, type I, alpha 1 | -0.123286 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.119728 |
| COL3A1 | collagen, type III, alpha 1 | -0.0964273 |
| RPL23 | ribosomal protein L23 | -0.0922119 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0774943 |
| RPS6 | ribosomal protein S6 | -0.0768738 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0762976 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0760904 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0759027 |
| VIM | vimentin | -0.0734075 |
| ACTG1 | actin gamma 1 | -0.0701172 |
| RPL19 | ribosomal protein L19 | -0.0687585 |
| RPLP1 | ribosomal protein, large, P1 | -0.0652095 |
| SYT1 | synaptotagmin I | -0.0643118 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0636009 |
| RNF213 | ring finger protein 213 | -0.0635214 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0620095 |
| RPL35A | ribosomal protein L35a | -0.0595764 |
| LSAMP | limbic system-associated membrane protein | -0.0568248 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0566779 |
| RPS24 | ribosomal protein S24 | -0.0552356 |
| TMSB10 | thymosin beta 10 | -0.0552221 |
| RPL38 | ribosomal protein L38 | -0.0532916 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0530854 |
| MAP1B | microtubule-associated protein 1B | -0.0515032 |
| FNBP1 | formin binding protein 1 | -0.0514164 |
| FRMD4A | FERM domain containing 4A | -0.0513314 |
| VCL | vinculin | -0.0488526 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0472967 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0449882 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0447571 |
| FAM107B | family with sequence similarity 107, member B | -0.0440744 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0436896 |
| RPL34 | ribosomal protein L34 | -0.0434187 |
| GNAS | GNAS complex locus | -0.0432354 |
| RIGI | RNA sensor RIG-I | -0.0430633 |
| B2M | beta-2-microglobulin | -0.0423309 |
| SIK2 | salt-inducible kinase 2 | -0.0418718 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0412569 |
| TLE4 | transducin-like enhancer of split 4 | -0.040793 |
| LMNA | lamin A/C | -0.0402511 |
| NDRG1 | N-myc downstream regulated 1 | -0.0389659 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0386466 |
| PLPP1 | phospholipid phosphatase 1 | -0.0385018 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0380354 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0375531 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0372544 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0368238 |
| RPL26 | ribosomal protein L26 | -0.0367225 |
| CANX | calnexin | -0.0365026 |
| GLCCI1 | glucocorticoid induced 1 | -0.0356417 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0356286 |
| FOXO3 | forkhead box O3 | -0.0355562 |
| SP100 | SP100 nuclear antigen | -0.0355493 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0351633 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0351391 |
| TRIB2 | tribbles pseudokinase 2 | -0.0350056 |
| PKM | pyruvate kinase, muscle | -0.0349144 |
| RPL32 | ribosomal protein L32 | -0.0348321 |
| RPL36 | ribosomal protein L36 | -0.0342989 |
| WDR45B | WD repeat domain 45B | -0.0337597 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.033522 |
| NREP | neuronal regeneration related protein | -0.0332865 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0329059 |
| RPS19 | ribosomal protein S19 | -0.0328473 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0327283 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0323075 |
| RBM25 | RNA binding motif protein 25 | -0.0321702 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0315143 |
| RPLP0 | ribosomal protein, large, P0 | -0.0315108 |
| MYO9A | myosin IXA | -0.0314457 |
| S100A9 | S100 calcium binding protein A9 | -0.0305451 |
| AOPEP | aminopeptidase O (putative) | -0.0301309 |
| RPS23 | ribosomal protein S23 | -0.030072 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0299461 |
| ARF1 | ADP-ribosylation factor 1 | -0.0297595 |
| EGR1 | early growth response 1 | -0.029548 |
| KLHL13 | kelch-like family member 13 | -0.0293921 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0292328 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0290809 |
| DISP1 | dispatched homolog 1 (Drosophila) | -0.0290587 |
| PDE10A | phosphodiesterase 10A | -0.0289486 |
| RPS21 | ribosomal protein S21 | -0.028859 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0288392 |
| NBEA | neurobeachin | -0.0287813 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0287266 |
| RPS29 | ribosomal protein S29 | -0.0286528 |
| BPTF | bromodomain PHD finger transcription factor | -0.0286272 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0283507 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0274621 |
| MT2A | metallothionein 2A | -0.0273402 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0273347 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0270637 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0268014 |
| ACTN4 | actinin, alpha 4 | -0.0267861 |
| GRK5 | G protein-coupled receptor kinase 5 | -0.026769 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0266423 |
