| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clobetasol propionate perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clobetasol propionate_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LOX | lysyl oxidase | 0.0814538 |
| TNS3 | tensin 3 | 0.0659746 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.064277 |
| TSC22D3 | TSC22 domain family, member 3 | 0.0627028 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0589872 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0546927 |
| MT1X | metallothionein 1X | 0.0522872 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0520236 |
| FAM13A | family with sequence similarity 13, member A | 0.0501672 |
| MT2A | metallothionein 2A | 0.0487184 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0481472 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0451782 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0376496 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0368178 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0367737 |
| FKBP5 | FK506 binding protein 5 | 0.0365328 |
| JAK1 | Janus kinase 1 | 0.0364505 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0359331 |
| PHF21A | PHD finger protein 21A | 0.0348903 |
| ELMO1 | engulfment and cell motility 1 | 0.0342374 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0340198 |
| PRELID2 | PRELI domain containing 2 | 0.0338185 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0325 |
| SH3RF3 | SH3 domain containing ring finger 3 | 0.032325 |
| NNMT | nicotinamide N-methyltransferase | 0.0322455 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0315345 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0312808 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0305569 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0301277 |
| DNAH5 | dynein, axonemal, heavy chain 5 | 0.0299566 |
| OGA | O-GlcNAcase | 0.0295385 |
| DNER | delta/notch-like EGF repeat containing | 0.0293006 |
| SNX13 | sorting nexin 13 | 0.0286243 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0284473 |
| PCNX1 | pecanex 1 | 0.027934 |
| TUT4 | terminal uridylyl transferase 4 | 0.0278821 |
| HIP1 | huntingtin interacting protein 1 | 0.0274355 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0264904 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0262392 |
| USP47 | ubiquitin specific peptidase 47 | 0.0261796 |
| COPA | coatomer protein complex, subunit alpha | 0.0261241 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0261049 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0261017 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0260671 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0258637 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0256659 |
| PHF3 | PHD finger protein 3 | 0.0244525 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0244045 |
| AHNAK | AHNAK nucleoprotein | 0.0241787 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0241577 |
| CCDC102B | coiled-coil domain containing 102B | 0.023986 |
| PCBP3 | poly(rC) binding protein 3 | 0.0235715 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0235469 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0233556 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0229847 |
| PTCHD4 | patched domain containing 4 | 0.022934 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0222183 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | 0.0221451 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0221276 |
| HOMER2 | homer scaffolding protein 2 | 0.02204 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0217057 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0216787 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 | 0.0215867 |
| KLF9 | Kruppel-like factor 9 | 0.0215425 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.021274 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0210452 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0210266 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0208888 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.020391 |
| RBM39 | RNA binding motif protein 39 | 0.0201978 |
| METTL15 | methyltransferase like 15 | 0.0201631 |
| CANX | calnexin | 0.0201306 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0200991 |
| SCFD2 | sec1 family domain containing 2 | 0.0200043 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0199962 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0198185 |
| PDZD2 | PDZ domain containing 2 | 0.019718 |
| CD109 | CD109 molecule | 0.0196692 |
| CDK13 | cyclin-dependent kinase 13 | 0.0193724 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.0191856 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.018964 |
| COG5 | component of oligomeric golgi complex 5 | 0.0188068 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.0187644 |
| IRS2 | insulin receptor substrate 2 | 0.0187241 |
| ZNF451 | zinc finger protein 451 | 0.0184304 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0184171 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0183502 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0182749 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0180555 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0179738 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0178654 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0178029 |
| LAMB1 | laminin, beta 1 | 0.0176635 |
| TOP1 | topoisomerase (DNA) I | 0.0176362 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0176342 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.017609 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.017516 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | 0.0174703 |
| HELZ | helicase with zinc finger | 0.0173775 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0173409 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.27816 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.212141 |
| VIM | vimentin | -0.182665 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.142526 |
| TMSB10 | thymosin beta 10 | -0.128176 |
| CD44 | CD44 molecule (Indian blood group) | -0.119564 |
| FTL | ferritin, light polypeptide | -0.110066 |
| ASPH | aspartate beta-hydroxylase | -0.100079 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0896885 |
| NDRG1 | N-myc downstream regulated 1 | -0.0894 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0866255 |
| B2M | beta-2-microglobulin | -0.0863907 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0861593 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0852425 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0848502 |
| PTMA | prothymosin, alpha | -0.0846521 |
| HLA-B | major histocompatibility complex, class I, B | -0.0831857 |
| TPM4 | tropomyosin 4 | -0.0808945 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0761997 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0728942 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0676888 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0662168 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0638742 |
| CALD1 | caldesmon 1 | -0.0595721 |
| PKM | pyruvate kinase, muscle | -0.0576326 |
| ENO1 | enolase 1, (alpha) | -0.0552544 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.052205 |
| STC1 | stanniocalcin 1 | -0.0520109 |
| DST | dystonin | -0.0508598 |
| HLA-A | major histocompatibility complex, class I, A | -0.0498785 |
| POTEF | POTE ankyrin domain family, member F | -0.0480831 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0473496 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0473062 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0463899 |
| NLGN1 | neuroligin 1 | -0.0462108 |
| NAV1 | neuron navigator 1 | -0.0461608 |
| PRSS23 | protease, serine, 23 | -0.0436611 |
| RPL35A | ribosomal protein L35a | -0.043471 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0429576 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0429205 |
| RPS6 | ribosomal protein S6 | -0.0422128 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0403523 |
| RPS8 | ribosomal protein S8 | -0.040126 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0398495 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0376834 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.037505 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0371987 |
| GNAS | GNAS complex locus | -0.0370224 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0370157 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0370128 |
| IGF2 | insulin-like growth factor 2 | -0.0365095 |
| NAV3 | neuron navigator 3 | -0.0358232 |
| ACTG1 | actin gamma 1 | -0.0352389 |
| LOXL2 | lysyl oxidase-like 2 | -0.0349585 |
| TPI1 | triosephosphate isomerase 1 | -0.0347886 |
| MAP1B | microtubule-associated protein 1B | -0.0330277 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0323976 |
| MKI67 | marker of proliferation Ki-67 | -0.031703 |
| SEC61G | Sec61 gamma subunit | -0.0317008 |
| MYO10 | myosin X | -0.0313768 |
| CALR | calreticulin | -0.0313255 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0312642 |
| ACTN4 | actinin, alpha 4 | -0.03071 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0306598 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0305433 |
| DTNA | dystrobrevin, alpha | -0.0301735 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0299674 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0296621 |
| INHBA | inhibin, beta A | -0.0292497 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0282365 |
| MYLK | myosin light chain kinase | -0.0279548 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0279223 |
| PGK1 | phosphoglycerate kinase 1 | -0.0278171 |
| RPL37A | ribosomal protein L37a | -0.027167 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0269095 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0266219 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0259983 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0258191 |
| RPL31 | ribosomal protein L31 | -0.0256533 |
| RPLP2 | ribosomal protein, large, P2 | -0.0255206 |
| CENPF | centromere protein F, 350/400kDa | -0.0254655 |
| CCND1 | cyclin D1 | -0.0254143 |
| S100A6 | S100 calcium binding protein A6 | -0.0253342 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0252623 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0252124 |
| LMNA | lamin A/C | -0.0249545 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0247215 |
| COL5A1 | collagen, type V, alpha 1 | -0.0245196 |
| RPL23 | ribosomal protein L23 | -0.024471 |
| S100A9 | S100 calcium binding protein A9 | -0.0243031 |
| LYPD6B | LY6/PLAUR domain containing 6B | -0.024167 |
| RPS13 | ribosomal protein S13 | -0.0240107 |
| RPLP1 | ribosomal protein, large, P1 | -0.0239855 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0239491 |
| PTK2 | protein tyrosine kinase 2 | -0.0232409 |
| RPS19 | ribosomal protein S19 | -0.0232401 |
| EGR1 | early growth response 1 | -0.0231997 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0229844 |
| HLA-C | major histocompatibility complex, class I, C | -0.0229603 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0229324 |
