| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clobetasol propionate perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clobetasol propionate_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.139057 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.135024 |
| GOLGA4 | golgin A4 | 0.0555901 |
| CANX | calnexin | 0.0453101 |
| AHNAK | AHNAK nucleoprotein | 0.0440658 |
| APP | amyloid beta (A4) precursor protein | 0.0438622 |
| ZNF292 | zinc finger protein 292 | 0.0385295 |
| RPL7 | ribosomal protein L7 | 0.0353178 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0347214 |
| CALR | calreticulin | 0.0332301 |
| HDLBP | high density lipoprotein binding protein | 0.0315147 |
| RNF145 | ring finger protein 145 | 0.0303158 |
| HELZ | helicase with zinc finger | 0.0298708 |
| OGA | O-GlcNAcase | 0.0278172 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0275852 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0273252 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0273164 |
| AFDN | afadin, adherens junction formation factor | 0.0266711 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0260024 |
| RPL12 | ribosomal protein L12 | 0.0257703 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0257156 |
| RLF | rearranged L-myc fusion | 0.0254085 |
| MATR3 | matrin 3 | 0.0238178 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0235126 |
| PGK1 | phosphoglycerate kinase 1 | 0.0233356 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.0228682 |
| RPL13A | ribosomal protein L13a | 0.0227709 |
| FLNA | filamin A, alpha | 0.0226729 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.022582 |
| TFG | TRK-fused gene | 0.0225431 |
| SEC24D | SEC24 family member D | 0.0224401 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0218382 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.021545 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0214693 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0213954 |
| GOLGB1 | golgin B1 | 0.0212674 |
| PHF3 | PHD finger protein 3 | 0.0212335 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0210058 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.020963 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0208059 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0205617 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0205292 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0204925 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0204697 |
| CLINT1 | clathrin interactor 1 | 0.0204307 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0203888 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0199738 |
| MTDH | metadherin | 0.0198429 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.019755 |
| RPL35A | ribosomal protein L35a | 0.0196116 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0193615 |
| SPOPL | speckle-type POZ protein-like | 0.0192724 |
| GOLGA2 | golgin A2 | 0.0191834 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0190817 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0189013 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0187052 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0186515 |
| RPL4 | ribosomal protein L4 | 0.018419 |
| RPL26 | ribosomal protein L26 | 0.018351 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.0182917 |
| COG5 | component of oligomeric golgi complex 5 | 0.0181674 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | 0.0181091 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0180996 |
| NCKAP1 | NCK-associated protein 1 | 0.0180414 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.017872 |
| RPL23 | ribosomal protein L23 | 0.0177188 |
| UBQLN1 | ubiquilin 1 | 0.0176021 |
| USP3 | ubiquitin specific peptidase 3 | 0.0173083 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0171344 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0171224 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0170888 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0169899 |
| YTHDC1 | YTH domain containing 1 | 0.0169751 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0169528 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0169481 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.016831 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0166644 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0166246 |
| DNAJC25 | DnaJ (Hsp40) homolog, subfamily C , member 25 | 0.0165765 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0165716 |
| RPL19 | ribosomal protein L19 | 0.0165561 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0164864 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0163574 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.0162996 |
| UBXN7 | UBX domain protein 7 | 0.0162414 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0161814 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0159568 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0159369 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0159258 |
| NUP58 | nucleoporin 58 | 0.0159172 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0157193 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0156861 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0156725 |
| PGM3 | phosphoglucomutase 3 | 0.0156588 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.015597 |
| CASC3 | cancer susceptibility candidate 3 | 0.0155237 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0153062 |
| NDFIP1 | Nedd4 family interacting protein 1 | 0.0151201 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0151152 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0150652 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.109452 |
| ASPH | aspartate beta-hydroxylase | -0.0993031 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0899551 |
| POTEF | POTE ankyrin domain family, member F | -0.0898177 |
| TMSB10 | thymosin beta 10 | -0.0858419 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0748743 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0746904 |
| FHIT | fragile histidine triad | -0.0738195 |
| EGR1 | early growth response 1 | -0.0710884 |
| CD44 | CD44 molecule (Indian blood group) | -0.0710865 |
| TPM4 | tropomyosin 4 | -0.0691848 |
| PKM | pyruvate kinase, muscle | -0.0676838 |
| LAMC2 | laminin, gamma 2 | -0.0654609 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0604344 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0602988 |
| KRT7 | keratin 7, type II | -0.0600712 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0598639 |
| HMGA2 | high mobility group AT-hook 2 | -0.0561986 |
| SVIL | supervillin | -0.055656 |
| RAD51B | RAD51 paralog B | -0.0546407 |
| NDRG1 | N-myc downstream regulated 1 | -0.0544283 |
| ACTG1 | actin gamma 1 | -0.0537064 |
| BPTF | bromodomain PHD finger transcription factor | -0.0516253 |
| HMGA1 | high mobility group AT-hook 1 | -0.0515132 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0511964 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0511277 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.051079 |
| MACROD2 | MACRO domain containing 2 | -0.0497609 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0465288 |
| PTMA | prothymosin, alpha | -0.0430406 |
| ACTN4 | actinin, alpha 4 | -0.0407689 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0401401 |
| PFN1 | profilin 1 | -0.0391972 |
| PAX8 | paired box 8 | -0.0386996 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0384937 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.037807 |
| CBX3 | chromobox homolog 3 | -0.0373615 |
| WWOX | WW domain containing oxidoreductase | -0.0360314 |
| VCL | vinculin | -0.0349985 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0344812 |
| LAMA4 | laminin, alpha 4 | -0.0342143 |
| ITGA6 | integrin, alpha 6 | -0.0339321 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0334286 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0325162 |
| SMYD3 | SET and MYND domain containing 3 | -0.0323917 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0321624 |
| VMP1 | vacuole membrane protein 1 | -0.0316052 |
| CCND1 | cyclin D1 | -0.031492 |
| MT2A | metallothionein 2A | -0.0302072 |
| RUNX1 | runt-related transcription factor 1 | -0.029716 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0295777 |
| EREG | epiregulin | -0.0294333 |
| VCAN | versican | -0.0292372 |
| HELLS | helicase, lymphoid-specific | -0.0290145 |
| DARS1 | aspartyl-tRNA synthetase 1 | -0.0289522 |
| TUBA1B | tubulin, alpha 1b | -0.028877 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0288327 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0285467 |
| PCED1B | PC-esterase domain containing 1B | -0.0285334 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0284151 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0279716 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0274019 |
| ATG7 | autophagy related 7 | -0.0270404 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.026955 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0269541 |
| ZFHX3 | zinc finger homeobox 3 | -0.0268922 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0268249 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0266956 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0263495 |
| GNAS | GNAS complex locus | -0.0263297 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0260756 |
| ATXN1 | ataxin 1 | -0.0258818 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0258409 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0257995 |
| SUMF1 | sulfatase modifying factor 1 | -0.0254517 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.025141 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0247579 |
| TPI1 | triosephosphate isomerase 1 | -0.0243194 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0242074 |
| MYADM | myeloid-associated differentiation marker | -0.0240183 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0239144 |
| DIAPH3 | diaphanous-related formin 3 | -0.0237627 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.023727 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0236738 |
| CLDN4 | claudin 4 | -0.0236241 |
| DIAPH2 | diaphanous-related formin 2 | -0.0234132 |
| PRELID2 | PRELI domain containing 2 | -0.0233833 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0232828 |
| S100A6 | S100 calcium binding protein A6 | -0.0232186 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0228695 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0228386 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0227644 |
| TXNRD1 | thioredoxin reductase 1 | -0.022661 |
| TAPBP | TAP binding protein (tapasin) | -0.022522 |
| SMC1A | structural maintenance of chromosomes 1A | -0.0224741 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0223918 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0223061 |
| RBM25 | RNA binding motif protein 25 | -0.0222482 |
| MYO1E | myosin IE | -0.0217152 |
| LDHA | lactate dehydrogenase A | -0.0215674 |
