| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clobetasol propionate perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clobetasol propionate_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.281562 |
| FKBP5 | FK506 binding protein 5 | 0.127568 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.121612 |
| MT2A | metallothionein 2A | 0.117403 |
| LOX | lysyl oxidase | 0.115093 |
| SH3RF3 | SH3 domain containing ring finger 3 | 0.111298 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.10924 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.104123 |
| PCBP3 | poly(rC) binding protein 3 | 0.0987551 |
| FNDC3B | fibronectin type III domain containing 3B | 0.098001 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0977895 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0881759 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0834922 |
| AHNAK | AHNAK nucleoprotein | 0.0794383 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0691554 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0679269 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0677838 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0673801 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0644175 |
| MYOF | myoferlin | 0.0631393 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0629272 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0569022 |
| DNER | delta/notch-like EGF repeat containing | 0.055027 |
| FAM13A | family with sequence similarity 13, member A | 0.0534977 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0489673 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0486922 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0475534 |
| LDHA | lactate dehydrogenase A | 0.0467998 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0444834 |
| MT1X | metallothionein 1X | 0.0434712 |
| TSC22D3 | TSC22 domain family, member 3 | 0.0434091 |
| MT1E | metallothionein 1E | 0.0433159 |
| CD109 | CD109 molecule | 0.0417342 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0406049 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0394456 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0393704 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.038994 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0387791 |
| PCNX1 | pecanex 1 | 0.0382842 |
| TNS3 | tensin 3 | 0.0372799 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0372157 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0369635 |
| RNF220 | ring finger protein 220 | 0.0368141 |
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | 0.0361443 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0361357 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0344172 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0334601 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0326803 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.031814 |
| LDLRAD3 | low density lipoprotein receptor class A domain containing 3 | 0.0317159 |
| IRS2 | insulin receptor substrate 2 | 0.031594 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0314329 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.0300552 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0299275 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0297252 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0294886 |
| TRAM2 | translocation associated membrane protein 2 | 0.0294094 |
| EFNA5 | ephrin-A5 | 0.0292491 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0288462 |
| JAK1 | Janus kinase 1 | 0.028412 |
| MED13L | mediator complex subunit 13-like | 0.0281291 |
| PRKCE | protein kinase C, epsilon | 0.0280168 |
| RUNX1 | runt-related transcription factor 1 | 0.0279873 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.0275303 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0274723 |
| PHF21A | PHD finger protein 21A | 0.0269621 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.025639 |
| SLTM | SAFB-like, transcription modulator | 0.0249158 |
| CCND3 | cyclin D3 | 0.0244308 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0244167 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | 0.0242412 |
| GOLGA4 | golgin A4 | 0.0241608 |
| LAMB1 | laminin, beta 1 | 0.0235678 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0233197 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0232906 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0232815 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0229782 |
| BCL2L1 | BCL2-like 1 | 0.0229212 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0226095 |
| JCAD | junctional cadherin 5 associated | 0.0224995 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0223532 |
| ANGPTL4 | angiopoietin-like 4 | 0.0222353 |
| CUL4B | cullin 4B | 0.0221837 |
| SETD5 | SET domain containing 5 | 0.0219483 |
| GPC6 | glypican 6 | 0.0219168 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0217696 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0210794 |
| PHKB | phosphorylase kinase, beta | 0.0208546 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0206113 |
| METTL15 | methyltransferase like 15 | 0.0205425 |
| PRELID2 | PRELI domain containing 2 | 0.0204757 |
| MAPK14 | mitogen-activated protein kinase 14 | 0.0204552 |
| ARMC8 | armadillo repeat containing 8 | 0.0203858 |
| HIP1 | huntingtin interacting protein 1 | 0.0201872 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0200459 |
| CANX | calnexin | 0.0200231 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0199937 |
| JPH2 | junctophilin 2 | 0.019967 |
| DENND3 | DENN/MADD domain containing 3 | 0.0198062 |
| RPL7 | ribosomal protein L7 | 0.0197792 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.240353 |
| CD44 | CD44 molecule (Indian blood group) | -0.165341 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.160207 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.152783 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.145037 |
| EXT1 | exostosin glycosyltransferase 1 | -0.140768 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.134998 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.131061 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.119703 |
| NDRG1 | N-myc downstream regulated 1 | -0.09095 |
| CDH13 | cadherin 13 | -0.0907565 |
| PDE10A | phosphodiesterase 10A | -0.0865423 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0842938 |
| STC1 | stanniocalcin 1 | -0.0822446 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0771658 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0768696 |
| CDCP1 | CUB domain containing protein 1 | -0.0730608 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0707849 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0619972 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0566791 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0563393 |
| PTMA | prothymosin, alpha | -0.0541727 |
| COL5A1 | collagen, type V, alpha 1 | -0.0541393 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0527091 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0502532 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0485328 |
| DTNA | dystrobrevin, alpha | -0.0479237 |
| NAV1 | neuron navigator 1 | -0.046826 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0466968 |
| IGF2 | insulin-like growth factor 2 | -0.0463172 |
| EGR1 | early growth response 1 | -0.0456493 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.045486 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0444945 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0443984 |
| CCND1 | cyclin D1 | -0.044283 |
| LAMB3 | laminin, beta 3 | -0.0424208 |
| MYO10 | myosin X | -0.0401396 |
| INHBA | inhibin, beta A | -0.0397454 |
| SMAD3 | SMAD family member 3 | -0.0393403 |
| ACTN4 | actinin, alpha 4 | -0.0379018 |
| RASA3 | RAS p21 protein activator 3 | -0.0359457 |
| TENM2 | teneurin transmembrane protein 2 | -0.0346804 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0343727 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0336365 |
| IL1B | interleukin 1, beta | -0.0331646 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0330365 |
| MAP1B | microtubule-associated protein 1B | -0.0328498 |
| GRB10 | growth factor receptor-bound protein 10 | -0.032575 |
| RAI14 | retinoic acid induced 14 | -0.0318262 |
| LOXL2 | lysyl oxidase-like 2 | -0.0314464 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0314452 |
| TUBB6 | tubulin, beta 6 class V | -0.031156 |
| NGLY1 | N-glycanase 1 | -0.0309669 |
| ACTG1 | actin gamma 1 | -0.030299 |
| TNNC1 | troponin C type 1 (slow) | -0.0297256 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0287971 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0285632 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0285067 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0282647 |
| CFAP20DC | CFAP20 domain containing | -0.0279424 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0278074 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0276498 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0275989 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0273764 |
| IER3 | immediate early response 3 | -0.0269816 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0266676 |
| CADM1 | cell adhesion molecule 1 | -0.0265414 |
| VEGFC | vascular endothelial growth factor C | -0.0265371 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0264334 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.026053 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0259916 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0257295 |
| GLIS3 | GLIS family zinc finger 3 | -0.0252259 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0250497 |
| RNF24 | ring finger protein 24 | -0.0248329 |
| IL11 | interleukin 11 | -0.0245574 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0238372 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0228699 |
| GNAS | GNAS complex locus | -0.0221252 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0216872 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.021638 |
| SYNJ2 | synaptojanin 2 | -0.0214204 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0213249 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0212903 |
| VEGFA | vascular endothelial growth factor A | -0.021271 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0207998 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | -0.0207738 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0206311 |
| AXL | AXL receptor tyrosine kinase | -0.0203578 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0201221 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0200567 |
| LAMA4 | laminin, alpha 4 | -0.0199374 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0198156 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0197944 |
| MYO9B | myosin IXB | -0.019791 |
| JUN | jun proto-oncogene | -0.0194744 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0193085 |
| PLEKHG4B | pleckstrin homology domain containing, family G (with RhoGef domain) member 4B | -0.0186779 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0185911 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0185474 |
