| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clobetasol propionate perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clobetasol propionate_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.276115 |
| APOB | apolipoprotein B | 0.248557 |
| C3 | complement component 3 | 0.155393 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.119898 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.104911 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.100292 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0790152 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.071558 |
| GPC6 | glypican 6 | 0.0696654 |
| VCL | vinculin | 0.0688649 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0615068 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0492215 |
| FKBP5 | FK506 binding protein 5 | 0.0473989 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0425334 |
| MRTFA | myocardin related transcription factor A | 0.0415905 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0407058 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0405153 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0395658 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0395494 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0393007 |
| MATN3 | matrilin 3 | 0.0353075 |
| ZNF644 | zinc finger protein 644 | 0.0351771 |
| TF | transferrin | 0.0338266 |
| ITGAV | integrin, alpha V | 0.033826 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | 0.0334919 |
| DNAH17 | dynein, axonemal, heavy chain 17 | 0.0325614 |
| FGA | fibrinogen alpha chain | 0.0325204 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0317815 |
| SLC23A1 | solute carrier family 23 (ascorbic acid transporter), member 1 | 0.0317744 |
| A2M | alpha-2-macroglobulin | 0.0316186 |
| BCL2L1 | BCL2-like 1 | 0.0306721 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0306394 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0296456 |
| FN1 | fibronectin 1 | 0.029545 |
| MBNL3 | muscleblind-like splicing regulator 3 | 0.0289516 |
| PCBP2 | poly(rC) binding protein 2 | 0.0288394 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0286449 |
| PTCHD4 | patched domain containing 4 | 0.0281062 |
| ITGA1 | integrin, alpha 1 | 0.027768 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0273126 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0272749 |
| LAMB1 | laminin, beta 1 | 0.0266827 |
| FHIT | fragile histidine triad | 0.0264542 |
| FGL1 | fibrinogen-like 1 | 0.0264154 |
| SMYD3 | SET and MYND domain containing 3 | 0.026254 |
| FGG | fibrinogen gamma chain | 0.0255717 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.025485 |
| FOXN3 | forkhead box N3 | 0.025391 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0242763 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0242351 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.023944 |
| IFNGR1 | interferon gamma receptor 1 | 0.0235901 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0230523 |
| CFB | complement factor B | 0.0229879 |
| DNAH5 | dynein, axonemal, heavy chain 5 | 0.0226655 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0221435 |
| RSU1 | Ras suppressor protein 1 | 0.0217915 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0213525 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0211625 |
| ACSS3 | acyl-CoA synthetase short-chain family member 3 | 0.0210233 |
| ADIPOR2 | adiponectin receptor 2 | 0.0209921 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0207312 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.020727 |
| PCM1 | pericentriolar material 1 | 0.0204751 |
| RBM39 | RNA binding motif protein 39 | 0.0201681 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.020154 |
| VIL1 | villin 1 | 0.0199745 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0193273 |
| SYN3 | synapsin III | 0.0193024 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0192667 |
| PDGFC | platelet derived growth factor C | 0.019142 |
| IL4R | interleukin 4 receptor | 0.0190773 |
| AOPEP | aminopeptidase O (putative) | 0.018886 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0188151 |
| SYNJ2 | synaptojanin 2 | 0.0187785 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0187713 |
| SFTPA2 | surfactant protein A2 | 0.0185868 |
| RELL1 | RELT-like 1 | 0.0185203 |
| DSPP | dentin sialophosphoprotein | 0.0184907 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0183887 |
| WDR43 | WD repeat domain 43 | 0.0182603 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0181165 |
| SGMS1 | sphingomyelin synthase 1 | 0.0180438 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.0180268 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0175611 |
| SELENOP | selenoprotein P | 0.017454 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0173923 |
| SKI | SKI proto-oncogene | 0.0173742 |
| DIAPH1 | diaphanous-related formin 1 | 0.0172048 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0172 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.0170048 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0169817 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0169453 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0169443 |
| IL6ST | interleukin 6 signal transducer | 0.0167866 |
| ANXA5 | annexin A5 | 0.0166475 |
| ORM1 | orosomucoid 1 | 0.0166452 |
| YAP1 | Yes-associated protein 1 | 0.0165551 |
| EXOC4 | exocyst complex component 4 | 0.0163376 |
| SIK2 | salt-inducible kinase 2 | 0.0163038 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.336469 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0949301 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0861876 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0733227 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0732461 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0712162 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0700121 |
| ENO1 | enolase 1, (alpha) | -0.0665498 |
| NDRG1 | N-myc downstream regulated 1 | -0.0627676 |
| DTNA | dystrobrevin, alpha | -0.060081 |
| FRMD5 | FERM domain containing 5 | -0.060045 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0589362 |
| RPS6 | ribosomal protein S6 | -0.0571493 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0570305 |
| RPLP1 | ribosomal protein, large, P1 | -0.0569288 |
| FTL | ferritin, light polypeptide | -0.0545464 |
| ASPH | aspartate beta-hydroxylase | -0.0531123 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0520675 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0507942 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0481417 |
| APOA2 | apolipoprotein A-II | -0.0446656 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.044496 |
| RPL35A | ribosomal protein L35a | -0.0437931 |
| KIAA1217 | KIAA1217 | -0.0434605 |
| RPL37A | ribosomal protein L37a | -0.0434046 |
| MT2A | metallothionein 2A | -0.040436 |
| FMNL2 | formin-like 2 | -0.0394994 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0394283 |
| ATXN1 | ataxin 1 | -0.0394039 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0390509 |
| RPS19 | ribosomal protein S19 | -0.0389357 |
| HMGA1 | high mobility group AT-hook 1 | -0.0382223 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0380962 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | -0.0362902 |
| DST | dystonin | -0.034801 |
| ATP10A | ATPase, class V, type 10A | -0.034359 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.033796 |
| PLIN2 | perilipin 2 | -0.0336921 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0332582 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0326036 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.0321587 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0319413 |
| TMSB10 | thymosin beta 10 | -0.0308102 |
| RPL23 | ribosomal protein L23 | -0.0307962 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0306083 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0302261 |
| RPS29 | ribosomal protein S29 | -0.0294717 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0293534 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0286282 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.028238 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0281849 |
| RPL12 | ribosomal protein L12 | -0.0278275 |
| INSIG2 | insulin induced gene 2 | -0.0277946 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0277141 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0276018 |
| PRELID2 | PRELI domain containing 2 | -0.0272133 |
| RPS27A | ribosomal protein S27a | -0.026796 |
| RPS24 | ribosomal protein S24 | -0.0265178 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0261364 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0260909 |
| PGK1 | phosphoglycerate kinase 1 | -0.0260375 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0259956 |
| LDHA | lactate dehydrogenase A | -0.025984 |
| ARFGEF3 | ARFGEF family member 3 | -0.0259547 |
| GK | glycerol kinase | -0.0258951 |
| WDR45B | WD repeat domain 45B | -0.0258944 |
| INTS6 | integrator complex subunit 6 | -0.0254211 |
| RPL36 | ribosomal protein L36 | -0.0252801 |
| MXI1 | MAX interactor 1, dimerization protein | -0.024926 |
| PKM | pyruvate kinase, muscle | -0.0248265 |
| RPS21 | ribosomal protein S21 | -0.0248211 |
| FAM13A | family with sequence similarity 13, member A | -0.024532 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.0238055 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0236578 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0236003 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0235132 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0233527 |
| H1-0 | H1.0 linker histone | -0.02324 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0228956 |
| NGLY1 | N-glycanase 1 | -0.0228806 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0225738 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0224672 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0223889 |
| RNF213 | ring finger protein 213 | -0.0218275 |
| SQSTM1 | sequestosome 1 | -0.0217733 |
| PTMA | prothymosin, alpha | -0.0216895 |
| RPLP2 | ribosomal protein, large, P2 | -0.0210888 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0208961 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | -0.0208915 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0202436 |
| RPS8 | ribosomal protein S8 | -0.0201715 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0200919 |
| FLNB | filamin B, beta | -0.0200042 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0199564 |
| GNAS | GNAS complex locus | -0.0198456 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0196748 |
| RPL34 | ribosomal protein L34 | -0.0194812 |
| RPS23 | ribosomal protein S23 | -0.0194687 |
| ARHGAP18 | Rho GTPase activating protein 18 | -0.0194195 |
| FBXO42 | F-box protein 42 | -0.0192665 |
