| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clobetasol propionate perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clobetasol propionate_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DLG1 | discs, large homolog 1 (Drosophila) | 0.128354 |
| MT2A | metallothionein 2A | 0.116869 |
| TOP1 | topoisomerase (DNA) I | 0.11567 |
| AHNAK | AHNAK nucleoprotein | 0.0938947 |
| MT1X | metallothionein 1X | 0.0921167 |
| MT1E | metallothionein 1E | 0.0905427 |
| FKBP5 | FK506 binding protein 5 | 0.0622712 |
| CANX | calnexin | 0.0534986 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0534717 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0518783 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0440655 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0424263 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0389852 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.038488 |
| TMSB4X | thymosin beta 4, X-linked | 0.0364589 |
| TMEM123 | transmembrane protein 123 | 0.0337225 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0336751 |
| TXNIP | thioredoxin interacting protein | 0.0335604 |
| EPHA4 | EPH receptor A4 | 0.0330632 |
| SRGN | serglycin | 0.0316229 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0314538 |
| PGK1 | phosphoglycerate kinase 1 | 0.0312183 |
| EHBP1 | EH domain binding protein 1 | 0.0298121 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0295967 |
| CADM2 | cell adhesion molecule 2 | 0.0290541 |
| HDAC9 | histone deacetylase 9 | 0.029013 |
| CALR | calreticulin | 0.0276157 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0275257 |
| EXOC4 | exocyst complex component 4 | 0.026754 |
| CFAP299 | cilia and flagella associated protein 299 | 0.0267127 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0266688 |
| APP | amyloid beta (A4) precursor protein | 0.0266128 |
| ITGB4 | integrin, beta 4 | 0.0260125 |
| RAD50 | RAD50 homolog (S. cerevisiae) | 0.0257525 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0254926 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0254653 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0245729 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0237534 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0235558 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0235174 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0220774 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0216244 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0215151 |
| DNER | delta/notch-like EGF repeat containing | 0.0210675 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0210529 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0207648 |
| HDLBP | high density lipoprotein binding protein | 0.0207402 |
| EGFR | epidermal growth factor receptor | 0.020647 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0202273 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0202132 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0200834 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0200541 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0200042 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.019862 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.0196656 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0196443 |
| LDHA | lactate dehydrogenase A | 0.0195864 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.019361 |
| PHF14 | PHD finger protein 14 | 0.0191177 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0191066 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0191047 |
| EFNA5 | ephrin-A5 | 0.018805 |
| SYT1 | synaptotagmin I | 0.0184815 |
| ATF7IP | activating transcription factor 7 interacting protein | 0.0177981 |
| PATJ | PATJ crumbs cell polarity complex component | 0.017717 |
| WDR27 | WD repeat domain 27 | 0.0177132 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0175126 |
| CDK6 | cyclin-dependent kinase 6 | 0.0173749 |
| MAT2A | methionine adenosyltransferase II, alpha | 0.0172792 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0171897 |
| THOC2 | THO complex 2 | 0.0171462 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0167992 |
| ANKRD50 | ankyrin repeat domain 50 | 0.0166311 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0164138 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0163374 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.0162833 |
| MDN1 | MDN1, midasin homolog (yeast) | 0.0162645 |
| CD109 | CD109 molecule | 0.0162576 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0162084 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0159085 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.0158959 |
| HDAC8 | histone deacetylase 8 | 0.0157872 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.015762 |
| RIGI | RNA sensor RIG-I | 0.0155546 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.015394 |
| LARP1 | La ribonucleoprotein domain family, member 1 | 0.0153523 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0152975 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.015103 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0150733 |
| KLF9 | Kruppel-like factor 9 | 0.0149189 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0145933 |
| ANXA2 | annexin A2 | 0.0145296 |
| RHBDD1 | rhomboid domain containing 1 | 0.0144559 |
| NSD1 | nuclear receptor binding SET domain protein 1 | 0.0142137 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0141068 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | 0.013901 |
| BPTF | bromodomain PHD finger transcription factor | 0.0138852 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0138829 |
| YARS1 | tyrosyl-tRNA synthetase 1 | 0.0138171 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0136615 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.250131 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.178525 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.128854 |
| POTEF | POTE ankyrin domain family, member F | -0.104792 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.10072 |
| DST | dystonin | -0.0976994 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0974447 |
| SPAG9 | sperm associated antigen 9 | -0.0902661 |
| RPS2 | ribosomal protein S2 | -0.0892004 |
| PTMA | prothymosin, alpha | -0.0822054 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.079827 |
| TXNRD1 | thioredoxin reductase 1 | -0.0770521 |
| HLA-B | major histocompatibility complex, class I, B | -0.0750541 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0698786 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0684776 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.064252 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0640155 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0610737 |
| CAPRIN2 | caprin family member 2 | -0.0599524 |
| RPS6 | ribosomal protein S6 | -0.0589785 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0580188 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.054649 |
| RTN4 | reticulon 4 | -0.0541917 |
| JMJD1C | jumonji domain containing 1C | -0.0539551 |
| LOXL2 | lysyl oxidase-like 2 | -0.0532912 |
| USP34 | ubiquitin specific peptidase 34 | -0.052997 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0528909 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0508631 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0504126 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0503617 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0496825 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0487412 |
| TMEM41B | transmembrane protein 41B | -0.0470084 |
| VMP1 | vacuole membrane protein 1 | -0.0464768 |
| RPS12 | ribosomal protein S12 | -0.046243 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0461066 |
| RPS19 | ribosomal protein S19 | -0.0458749 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0450735 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0442345 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0436828 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | -0.042987 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0424819 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.041832 |
| RRM2 | ribonucleotide reductase M2 | -0.0413376 |
| RPL37A | ribosomal protein L37a | -0.0410885 |
| FMNL2 | formin-like 2 | -0.040877 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0405456 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0405019 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0401593 |
| CDCP1 | CUB domain containing protein 1 | -0.0401449 |
| PDE10A | phosphodiesterase 10A | -0.0398573 |
| RPL36 | ribosomal protein L36 | -0.0396841 |
| RPLP2 | ribosomal protein, large, P2 | -0.039115 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0384976 |
| USP12 | ubiquitin specific peptidase 12 | -0.0374914 |
| PRDX1 | peroxiredoxin 1 | -0.0369803 |
| EZR | ezrin | -0.0368631 |
| RCOR1 | REST corepressor 1 | -0.0363946 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0360757 |
| RPL38 | ribosomal protein L38 | -0.0360272 |
| FERMT1 | fermitin family member 1 | -0.0357134 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0348092 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0335584 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | -0.0335204 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0333106 |
| BRD2 | bromodomain containing 2 | -0.0325354 |
| SRSF4 | serine/arginine-rich splicing factor 4 | -0.0325301 |
| CMIP | c-Maf inducing protein | -0.032403 |
| SEC24A | SEC24 family member A | -0.032279 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0321216 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0318669 |
| SDC4 | syndecan 4 | -0.0312109 |
| RPS8 | ribosomal protein S8 | -0.031023 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0305551 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0305491 |
| RPL26 | ribosomal protein L26 | -0.0304697 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0303468 |
| RPL28 | ribosomal protein L28 | -0.0300514 |
| FBXO11 | F-box protein 11 | -0.029968 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0298756 |
| ECE1 | endothelin converting enzyme 1 | -0.0298695 |
| NUP58 | nucleoporin 58 | -0.0298508 |
| TGM2 | transglutaminase 2 | -0.0295453 |
| SMAD3 | SMAD family member 3 | -0.0294855 |
| RPL37 | ribosomal protein L37 | -0.029397 |
| CEP170 | centrosomal protein 170kDa | -0.0291214 |
| CLTC | clathrin, heavy chain (Hc) | -0.0289067 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0286922 |
| TPM3 | tropomyosin 3 | -0.0286781 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0282672 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | -0.0282444 |
| YBX3 | Y box binding protein 3 | -0.0281748 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0281439 |
| B2M | beta-2-microglobulin | -0.0278924 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.027446 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0274413 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0273694 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0272897 |
| MKI67 | marker of proliferation Ki-67 | -0.027213 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0271507 |
