| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clobetasol propionate perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clobetasol propionate_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.172727 |
| FKBP5 | FK506 binding protein 5 | 0.129518 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.107104 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0884979 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0789625 |
| RBM39 | RNA binding motif protein 39 | 0.0730057 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0679669 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.06474 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0635099 |
| TOP1 | topoisomerase (DNA) I | 0.0602305 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0569683 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0569415 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0547349 |
| CD109 | CD109 molecule | 0.0537618 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0501147 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0491079 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0487673 |
| PCNX1 | pecanex 1 | 0.0476327 |
| TGM2 | transglutaminase 2 | 0.0469546 |
| ZBTB16 | zinc finger and BTB domain containing 16 | 0.0463826 |
| AHNAK | AHNAK nucleoprotein | 0.0443393 |
| PRELID2 | PRELI domain containing 2 | 0.0435938 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0430817 |
| FAM13A | family with sequence similarity 13, member A | 0.0426546 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0424916 |
| MYOF | myoferlin | 0.0424023 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0419752 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0414097 |
| NRCAM | neuronal cell adhesion molecule | 0.0404675 |
| OGA | O-GlcNAcase | 0.0387311 |
| GOLGA4 | golgin A4 | 0.037762 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0365343 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0363478 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0357714 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0353462 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0349606 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0347934 |
| USP34 | ubiquitin specific peptidase 34 | 0.0315783 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | 0.0311977 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.0304766 |
| PCBP2 | poly(rC) binding protein 2 | 0.0302834 |
| SETD5 | SET domain containing 5 | 0.0301391 |
| RAD51B | RAD51 paralog B | 0.0300198 |
| IL18R1 | interleukin 18 receptor 1 | 0.0295655 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0281621 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | 0.0278941 |
| MYO1E | myosin IE | 0.0276111 |
| ZHX3 | zinc fingers and homeoboxes 3 | 0.0275082 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0273665 |
| TTLL10 | tubulin tyrosine ligase-like family member 10 | 0.0271881 |
| IL1R1 | interleukin 1 receptor, type I | 0.0271463 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0269919 |
| SH3RF3 | SH3 domain containing ring finger 3 | 0.026873 |
| GPC6 | glypican 6 | 0.0265335 |
| JAK1 | Janus kinase 1 | 0.0259751 |
| COG5 | component of oligomeric golgi complex 5 | 0.0256162 |
| LDLRAD3 | low density lipoprotein receptor class A domain containing 3 | 0.025452 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0254096 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0243957 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0242745 |
| TSC22D3 | TSC22 domain family, member 3 | 0.0242328 |
| HOMER2 | homer scaffolding protein 2 | 0.0239557 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0238958 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0236792 |
| NEBL | nebulette | 0.0234534 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0232827 |
| RPGR | retinitis pigmentosa GTPase regulator | 0.023014 |
| SECISBP2L | SECIS binding protein 2-like | 0.0229303 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0228581 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0223099 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0223059 |
| NBAS | neuroblastoma amplified sequence | 0.0222894 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0222361 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0222334 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0222231 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0219209 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0218732 |
| YBX3 | Y box binding protein 3 | 0.0217028 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0215565 |
| MYO1B | myosin IB | 0.0213185 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0211915 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0210018 |
| SNX13 | sorting nexin 13 | 0.0208889 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0208175 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0207261 |
| TOX2 | TOX high mobility group box family member 2 | 0.020547 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0203383 |
| RPRD1B | regulation of nuclear pre-mRNA domain containing 1B | 0.0202775 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0202561 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0201334 |
| RTN4 | reticulon 4 | 0.0201262 |
| HELZ | helicase with zinc finger | 0.0200583 |
| IL6ST | interleukin 6 signal transducer | 0.0199645 |
| GPHN | gephyrin | 0.019939 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0199214 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0196666 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0195195 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0193336 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | 0.0191328 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0188972 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.201778 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.16973 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.130014 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.129552 |
| GRB10 | growth factor receptor-bound protein 10 | -0.122523 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.111765 |
| STC1 | stanniocalcin 1 | -0.10323 |
| CDH13 | cadherin 13 | -0.0886406 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.088488 |
| VIM | vimentin | -0.0841034 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0809368 |
| FAM20C | family with sequence similarity 20, member C | -0.0787284 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0769319 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0738917 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.071861 |
| GLCCI1 | glucocorticoid induced 1 | -0.0717976 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0710434 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0705578 |
| FN1 | fibronectin 1 | -0.0700108 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0696977 |
| MTSS1 | metastasis suppressor 1 | -0.0669477 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.065988 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0641715 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0617798 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.057845 |
| MEF2A | myocyte enhancer factor 2A | -0.0574546 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0561489 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0558905 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0520295 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0519729 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0518266 |
| CD44 | CD44 molecule (Indian blood group) | -0.0516035 |
| RAI14 | retinoic acid induced 14 | -0.0513937 |
| ETV6 | ets variant 6 | -0.0507845 |
| NDRG1 | N-myc downstream regulated 1 | -0.0492211 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0490294 |
| TMSB10 | thymosin beta 10 | -0.0478302 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0459833 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0459113 |
| FTL | ferritin, light polypeptide | -0.0454513 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0443277 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0423136 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0397401 |
| FBN1 | fibrillin 1 | -0.0385742 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0375513 |
| B2M | beta-2-microglobulin | -0.0369691 |
| CDCP1 | CUB domain containing protein 1 | -0.0368901 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0367619 |
| IER3 | immediate early response 3 | -0.0367333 |
| CDK14 | cyclin-dependent kinase 14 | -0.0365325 |
| PTMA | prothymosin, alpha | -0.036284 |
| LOXL2 | lysyl oxidase-like 2 | -0.0360238 |
| IL1B | interleukin 1, beta | -0.0341693 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0330314 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0326104 |
| EGFR | epidermal growth factor receptor | -0.0325159 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0323505 |
| MECOM | MDS1 and EVI1 complex locus | -0.0322376 |
| ATXN1 | ataxin 1 | -0.0319838 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0317224 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0313376 |
| NRG1 | neuregulin 1 | -0.031034 |
| ANXA10 | annexin A10 | -0.0306864 |
| IFI44L | interferon-induced protein 44-like | -0.0306346 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0303593 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0302169 |
| FRMD4A | FERM domain containing 4A | -0.0301743 |
| NAV1 | neuron navigator 1 | -0.0301595 |
| GLIS3 | GLIS family zinc finger 3 | -0.0299249 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.02964 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0295507 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0295199 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0293712 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0293292 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0287122 |
| AADAC | arylacetamide deacetylase | -0.0280279 |
| CA12 | carbonic anhydrase XII | -0.0277959 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0275823 |
| HLA-B | major histocompatibility complex, class I, B | -0.0275473 |
| EGR1 | early growth response 1 | -0.0274182 |
| SEPTIN9 | septin 9 | -0.0272433 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0268383 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0265187 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0260974 |
| RND3 | Rho family GTPase 3 | -0.026048 |
| VEGFA | vascular endothelial growth factor A | -0.025925 |
| SYNJ2 | synaptojanin 2 | -0.0257052 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0255025 |
| MYO10 | myosin X | -0.0254816 |
| EREG | epiregulin | -0.025467 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0253676 |
| PRRX1 | paired related homeobox 1 | -0.0251139 |
| PYGL | phosphorylase, glycogen, liver | -0.0248698 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0247941 |
| ZNF804A | zinc finger protein 804A | -0.0247631 |
| S100A6 | S100 calcium binding protein A6 | -0.0240688 |
| LOX | lysyl oxidase | -0.0239744 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.023922 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0238253 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0237795 |
