| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clobetasol propionate perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clobetasol propionate_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.201116 |
| MT2A | metallothionein 2A | 0.162142 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0902918 |
| NNMT | nicotinamide N-methyltransferase | 0.0793089 |
| EFNA5 | ephrin-A5 | 0.0574388 |
| FGA | fibrinogen alpha chain | 0.0570811 |
| UTRN | utrophin | 0.0487896 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0419223 |
| MT1X | metallothionein 1X | 0.0418878 |
| FGB | fibrinogen beta chain | 0.041838 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0418148 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0331689 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0330616 |
| SRGN | serglycin | 0.0323226 |
| LDHA | lactate dehydrogenase A | 0.0323001 |
| FGG | fibrinogen gamma chain | 0.0313717 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0288027 |
| FAM135A | family with sequence similarity 135, member A | 0.0285135 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0282681 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0282425 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0260553 |
| DNAH5 | dynein, axonemal, heavy chain 5 | 0.0238422 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0236724 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0219806 |
| ATF6 | activating transcription factor 6 | 0.0215163 |
| JAK1 | Janus kinase 1 | 0.0209729 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0204252 |
| CAVIN2 | caveolae associated protein 2 | 0.0201889 |
| AHNAK | AHNAK nucleoprotein | 0.0200637 |
| WDR43 | WD repeat domain 43 | 0.0199514 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0198502 |
| KLF6 | Kruppel-like factor 6 | 0.0194537 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0184677 |
| SPIDR | scaffolding protein involved in DNA repair | 0.018425 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.018158 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0177079 |
| BICC1 | BicC family RNA binding protein 1 | 0.0176935 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0171974 |
| KYNU | kynureninase | 0.0171703 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0166766 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0165036 |
| CD109 | CD109 molecule | 0.0163038 |
| RAD51B | RAD51 paralog B | 0.01624 |
| PRKD1 | protein kinase D1 | 0.0161219 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0159276 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0153089 |
| PER1 | period circadian clock 1 | 0.0149529 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | 0.0149188 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | 0.0146518 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0144261 |
| ZNF804A | zinc finger protein 804A | 0.0143335 |
| DTNB | dystrobrevin, beta | 0.0137835 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.01363 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0133682 |
| THSD7A | thrombospondin, type I, domain containing 7A | 0.0133199 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0131272 |
| FHIT | fragile histidine triad | 0.0128885 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0127244 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0124085 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0121562 |
| PDE10A | phosphodiesterase 10A | 0.0121492 |
| CCND3 | cyclin D3 | 0.0120274 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0119754 |
| ANXA2 | annexin A2 | 0.0118944 |
| WWOX | WW domain containing oxidoreductase | 0.0118171 |
| STOM | stomatin | 0.0117025 |
| SPECC1 | sperm antigen with calponin homology and coiled-coil domains 1 | 0.0114435 |
| TSC22D3 | TSC22 domain family, member 3 | 0.0112649 |
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.0111264 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0111034 |
| AK1 | adenylate kinase 1 | 0.0110195 |
| METAP2 | methionyl aminopeptidase 2 | 0.010762 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.010759 |
| PCBP2 | poly(rC) binding protein 2 | 0.0107451 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.010598 |
| MUSK | muscle, skeletal, receptor tyrosine kinase | 0.0104563 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0103217 |
| POU5F1 | POU class 5 homeobox 1 | 0.00999879 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.00997945 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.00996975 |
| LMO7 | LIM domain 7 | 0.00992556 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00984258 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00978783 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00978406 |
| DIDO1 | death inducer-obliterator 1 | 0.00951002 |
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | 0.00947553 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.00940706 |
| PHF20 | PHD finger protein 20 | 0.00938171 |
| RNF213 | ring finger protein 213 | 0.00933057 |
| AMBRA1 | autophagy/beclin-1 regulator 1 | 0.00932693 |
| EPHA5 | EPH receptor A5 | 0.00932601 |
| PMP22 | peripheral myelin protein 22 | 0.0093018 |
| FSIP2 | fibrous sheath interacting protein 2 | 0.00926748 |
| TNRC6B | trinucleotide repeat containing 6B | 0.00922239 |
| HDAC4 | histone deacetylase 4 | 0.00915032 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.00910872 |
| ITGA10 | integrin, alpha 10 | 0.00902739 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.00897393 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.00888061 |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 | 0.00885739 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.184379 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.162779 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0876403 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0865566 |
| VIM | vimentin | -0.0853015 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0843151 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0831908 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0794776 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0743855 |
| ASPH | aspartate beta-hydroxylase | -0.0731592 |
| RPS2 | ribosomal protein S2 | -0.0712974 |
| GRAMD1B | GRAM domain containing 1B | -0.0711187 |
| IER3 | immediate early response 3 | -0.0700263 |
| FTL | ferritin, light polypeptide | -0.0664358 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0617322 |
| STC1 | stanniocalcin 1 | -0.0608357 |
| ACTG1 | actin gamma 1 | -0.0598466 |
| POTEF | POTE ankyrin domain family, member F | -0.0540089 |
| CMIP | c-Maf inducing protein | -0.052352 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0508046 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0489583 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0482665 |
| RPL19 | ribosomal protein L19 | -0.0458054 |
| FAM107B | family with sequence similarity 107, member B | -0.0453627 |
| IGF2 | insulin-like growth factor 2 | -0.0445664 |
| TPM3 | tropomyosin 3 | -0.043572 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0435038 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0423641 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0422796 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0417835 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0404175 |
| RTN4 | reticulon 4 | -0.0398164 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0393229 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0391459 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0389087 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.038822 |
| HSPA8 | heat shock 70kDa protein 8 | -0.038085 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0375652 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0374109 |
| S100A6 | S100 calcium binding protein A6 | -0.0364609 |
| SVIL | supervillin | -0.0360647 |
| KIF5B | kinesin family member 5B | -0.0354625 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0341949 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0340891 |
| CDCP1 | CUB domain containing protein 1 | -0.0338779 |
| RPS12 | ribosomal protein S12 | -0.0337279 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0334974 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0334378 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0328844 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0328385 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0325296 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0320329 |
| PTMA | prothymosin, alpha | -0.0318113 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0317238 |
| TXNRD1 | thioredoxin reductase 1 | -0.0313804 |
| PKM | pyruvate kinase, muscle | -0.0308832 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0306605 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0305851 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0305466 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0305058 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0301123 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0300027 |
| NAV3 | neuron navigator 3 | -0.0290573 |
| ACTN1 | actinin, alpha 1 | -0.0289357 |
| RPS6 | ribosomal protein S6 | -0.0288996 |
| BMP6 | bone morphogenetic protein 6 | -0.028775 |
| FLNB | filamin B, beta | -0.0285942 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0283942 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0283827 |
| SMAD3 | SMAD family member 3 | -0.0283763 |
| PYGL | phosphorylase, glycogen, liver | -0.0281919 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0281112 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0279481 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0279022 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0278871 |
| RPS27A | ribosomal protein S27a | -0.0277535 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0274885 |
| FMNL2 | formin-like 2 | -0.0274601 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0273041 |
| RPL37A | ribosomal protein L37a | -0.0267234 |
| PFDN2 | prefoldin subunit 2 | -0.0266731 |
| IL6 | interleukin 6 | -0.0265712 |
| CD44 | CD44 molecule (Indian blood group) | -0.0264399 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0263184 |
| CLTC | clathrin, heavy chain (Hc) | -0.0262528 |
| MCL1 | myeloid cell leukemia 1 | -0.0253191 |
| RPS8 | ribosomal protein S8 | -0.0253178 |
| PRDX1 | peroxiredoxin 1 | -0.0252378 |
| HLA-B | major histocompatibility complex, class I, B | -0.0249115 |
| GOLGA4 | golgin A4 | -0.0249021 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0244681 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0242424 |
| UPP1 | uridine phosphorylase 1 | -0.0241951 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0240812 |
| RPLP1 | ribosomal protein, large, P1 | -0.0239343 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0237451 |
| CAVIN1 | caveolae associated protein 1 | -0.0236597 |
| ERBIN | erbb2 interacting protein | -0.0236381 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0230637 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0229862 |
