| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clobetasol propionate perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clobetasol propionate_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.196814 |
| MT2A | metallothionein 2A | 0.166982 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.143756 |
| FN1 | fibronectin 1 | 0.123856 |
| TMSB10 | thymosin beta 10 | 0.120151 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.117179 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0924086 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0884483 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0820146 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0815153 |
| TOP1 | topoisomerase (DNA) I | 0.0759799 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.075104 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0748738 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0727996 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0715932 |
| RBM39 | RNA binding motif protein 39 | 0.0712727 |
| CUL1 | cullin 1 | 0.0705394 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0697219 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.068636 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0651338 |
| HDLBP | high density lipoprotein binding protein | 0.0640672 |
| RYBP | RING1 and YY1 binding protein | 0.0636362 |
| ENO1 | enolase 1, (alpha) | 0.0606516 |
| VIM | vimentin | 0.0592397 |
| TXNIP | thioredoxin interacting protein | 0.0582095 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0581647 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0580885 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0577648 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0573812 |
| VCL | vinculin | 0.0564317 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0553797 |
| FKBP5 | FK506 binding protein 5 | 0.054361 |
| SYT1 | synaptotagmin I | 0.0542923 |
| NKTR | natural killer cell triggering receptor | 0.0539343 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0518063 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0514657 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0510743 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0501189 |
| NRG1 | neuregulin 1 | 0.0497205 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0495922 |
| FAT1 | FAT atypical cadherin 1 | 0.0491252 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0482651 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0480082 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0474536 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.046744 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0466783 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0459626 |
| RPS6 | ribosomal protein S6 | 0.0455064 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0453479 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0451057 |
| SLC38A2 | solute carrier family 38, member 2 | 0.044689 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0442428 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0441763 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0430664 |
| ASPH | aspartate beta-hydroxylase | 0.0420764 |
| AHNAK | AHNAK nucleoprotein | 0.041862 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0398776 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0396525 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0389769 |
| S100P | S100 calcium binding protein P | 0.0388444 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0387369 |
| OXR1 | oxidation resistance 1 | 0.0386941 |
| CANX | calnexin | 0.0373131 |
| JAK1 | Janus kinase 1 | 0.0367224 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0366959 |
| RTN4 | reticulon 4 | 0.0364288 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0362728 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0361322 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0360432 |
| LDHA | lactate dehydrogenase A | 0.0360222 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0359759 |
| TPD52 | tumor protein D52 | 0.0358895 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.035838 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0356397 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0353475 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0352441 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0349911 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0348141 |
| KLF6 | Kruppel-like factor 6 | 0.0345127 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0335727 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0334033 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0332208 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0328044 |
| RUNX1 | runt-related transcription factor 1 | 0.0321189 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.03201 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0310576 |
| COG5 | component of oligomeric golgi complex 5 | 0.0309776 |
| ANO6 | anoctamin 6 | 0.0309221 |
| KIZ | kizuna centrosomal protein | 0.0305786 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0305193 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0301394 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0299147 |
| TPM3 | tropomyosin 3 | 0.029829 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0296051 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0295365 |
| RPS8 | ribosomal protein S8 | 0.029339 |
| TFG | TRK-fused gene | 0.0288373 |
| FBXO11 | F-box protein 11 | 0.0288117 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0281787 |
| GOLGA4 | golgin A4 | 0.0280247 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GRB10 | growth factor receptor-bound protein 10 | -0.158665 |
| TXNRD1 | thioredoxin reductase 1 | -0.143933 |
| LAMB3 | laminin, beta 3 | -0.128252 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.079134 |
| MYO1E | myosin IE | -0.078279 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0698754 |
| KRT17 | keratin 17, type I | -0.0674637 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0665602 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0655905 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0649301 |
| KYNU | kynureninase | -0.0646274 |
| LMO7 | LIM domain 7 | -0.0644006 |
| ATOSA | atos homolog A | -0.0639304 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0621689 |
| JMJD1C | jumonji domain containing 1C | -0.0619975 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0619237 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0616066 |
| NDRG1 | N-myc downstream regulated 1 | -0.0614739 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0606372 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0596532 |
| SPAG9 | sperm associated antigen 9 | -0.0570054 |
| SVIL | supervillin | -0.056618 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0559582 |
| CMIP | c-Maf inducing protein | -0.0551586 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0535281 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0529276 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0525668 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0520546 |
| NF1 | neurofibromin 1 | -0.0512312 |
| LAMC2 | laminin, gamma 2 | -0.0497648 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0496835 |
| NAV2 | neuron navigator 2 | -0.0491863 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0488978 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0488913 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0488038 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.04808 |
| SQSTM1 | sequestosome 1 | -0.0479282 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0464978 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0458326 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0458249 |
| JUN | jun proto-oncogene | -0.045464 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0452159 |
| XPO1 | exportin 1 | -0.0449853 |
| FMNL2 | formin-like 2 | -0.0430181 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0411214 |
| FOXO3 | forkhead box O3 | -0.0410466 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0410368 |
| ERBIN | erbb2 interacting protein | -0.0409346 |
| NCOA1 | nuclear receptor coactivator 1 | -0.04058 |
| ABHD17C | abhydrolase domain containing 17C | -0.040477 |
| MUC16 | mucin 16, cell surface associated | -0.040362 |
| TJP1 | tight junction protein 1 | -0.0403483 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0398853 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0396599 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0391773 |
| USP3 | ubiquitin specific peptidase 3 | -0.0381178 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0377836 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0377029 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0369687 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.036875 |
| RORA | RAR-related orphan receptor A | -0.0367597 |
| SLC38A1 | solute carrier family 38, member 1 | -0.036649 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0364194 |
| SETD5 | SET domain containing 5 | -0.0360687 |
| MYO6 | myosin VI | -0.0360183 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0356537 |
| EZR | ezrin | -0.0355562 |
| ZNF207 | zinc finger protein 207 | -0.0351745 |
| PATJ | PATJ crumbs cell polarity complex component | -0.035168 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0350719 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0345926 |
| C1D | C1D nuclear receptor corepressor | -0.0344359 |
| USP34 | ubiquitin specific peptidase 34 | -0.0342484 |
| KIAA1217 | KIAA1217 | -0.0339738 |
| SMAD3 | SMAD family member 3 | -0.033955 |
| SEPTIN2 | septin 2 | -0.0335202 |
| INHBA | inhibin, beta A | -0.0334946 |
| LSAMP | limbic system-associated membrane protein | -0.0333224 |
| DENND1A | DENN/MADD domain containing 1A | -0.0327408 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0324715 |
| GPC6 | glypican 6 | -0.0322804 |
| RPL23 | ribosomal protein L23 | -0.0320586 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0320004 |
| RPS19 | ribosomal protein S19 | -0.0319377 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0315938 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0314965 |
| RAB10 | RAB10, member RAS oncogene family | -0.0312482 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0311942 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.030704 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0303129 |
| RIOK3 | RIO kinase 3 | -0.030233 |
| MMP12 | matrix metallopeptidase 12 | -0.0298676 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0298187 |
| PCM1 | pericentriolar material 1 | -0.0297792 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0297652 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0297385 |
| CDYL | chromodomain protein, Y-like | -0.0295698 |
| DST | dystonin | -0.0293536 |
| MYOF | myoferlin | -0.0291881 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0278423 |
