| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clobetasol propionate perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clobetasol propionate_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.112384 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.090764 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0873025 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0803621 |
| MCL1 | myeloid cell leukemia 1 | 0.0742621 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0735472 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.07094 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0667706 |
| TXNRD1 | thioredoxin reductase 1 | 0.0545499 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0527143 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0523313 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0522611 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0499387 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0492601 |
| RBM39 | RNA binding motif protein 39 | 0.043755 |
| YBX3 | Y box binding protein 3 | 0.0425069 |
| OGA | O-GlcNAcase | 0.0418245 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0408924 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0397397 |
| PDE10A | phosphodiesterase 10A | 0.038715 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0360363 |
| AEBP2 | AE binding protein 2 | 0.0353268 |
| ATP13A3 | ATPase type 13A3 | 0.0347592 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0346871 |
| HOMER1 | homer scaffolding protein 1 | 0.0341593 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0339659 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0329089 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0328966 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.03263 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0324706 |
| GPHN | gephyrin | 0.031242 |
| SETX | senataxin | 0.0309906 |
| INTS6 | integrator complex subunit 6 | 0.0309723 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.030629 |
| TPM3 | tropomyosin 3 | 0.0305806 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0303976 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0303326 |
| DOCK5 | dedicator of cytokinesis 5 | 0.030332 |
| COPA | coatomer protein complex, subunit alpha | 0.0303144 |
| JMJD1C | jumonji domain containing 1C | 0.0300071 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0297932 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0293731 |
| CUL3 | cullin 3 | 0.0293421 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0292691 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0291769 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0289747 |
| SPAG9 | sperm associated antigen 9 | 0.0289282 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0288675 |
| BRD2 | bromodomain containing 2 | 0.0287689 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0285814 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0283386 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0273415 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.025469 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0252107 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0251879 |
| CLTC | clathrin, heavy chain (Hc) | 0.0250003 |
| WWOX | WW domain containing oxidoreductase | 0.0249216 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0248662 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0247804 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0245895 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0242132 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0241389 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0240314 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0238896 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.023719 |
| RTN4 | reticulon 4 | 0.023647 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0233803 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.023227 |
| ARFGEF3 | ARFGEF family member 3 | 0.0228371 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0228346 |
| PDE8A | phosphodiesterase 8A | 0.0228129 |
| PRELID2 | PRELI domain containing 2 | 0.0227224 |
| ZZZ3 | zinc finger, ZZ-type containing 3 | 0.0226912 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | 0.022669 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0226508 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0226097 |
| TMEM41B | transmembrane protein 41B | 0.0223759 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0223429 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0222831 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0222338 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0221679 |
| UGGT1 | UDP-glucose glycoprotein glucosyltransferase 1 | 0.022117 |
| ANXA5 | annexin A5 | 0.0220296 |
| XPOT | exportin, tRNA | 0.0219203 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0218769 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0217823 |
| DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 | 0.0215845 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0215675 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.0214178 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0213585 |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like | 0.0213361 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0211925 |
| BRD4 | bromodomain containing 4 | 0.0210923 |
| VCP | valosin containing protein | 0.0210606 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0210521 |
| DIDO1 | death inducer-obliterator 1 | 0.0209829 |
| EFNA5 | ephrin-A5 | 0.0209519 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0208192 |
| CLIC4 | chloride intracellular channel 4 | 0.0208011 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0207575 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.0899779 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0790128 |
| SMAD3 | SMAD family member 3 | -0.0786146 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0768267 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0603723 |
| TPI1 | triosephosphate isomerase 1 | -0.0598203 |
| EXOC4 | exocyst complex component 4 | -0.0573707 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0515465 |
| BBX | bobby sox homolog (Drosophila) | -0.051251 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0511233 |
| NF1 | neurofibromin 1 | -0.0511204 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0500333 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0474041 |
| PFN1 | profilin 1 | -0.0465607 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0465552 |
| MMP12 | matrix metallopeptidase 12 | -0.0454589 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0453817 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0450001 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0449514 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0449398 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0446097 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0441487 |
| RNF213 | ring finger protein 213 | -0.044134 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0432576 |
| FTL | ferritin, light polypeptide | -0.0422897 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0416238 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0416232 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0411306 |
| ATXN1 | ataxin 1 | -0.0409634 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0406352 |
| EGFR | epidermal growth factor receptor | -0.0403764 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0401597 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0400139 |
| EHBP1 | EH domain binding protein 1 | -0.0396358 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0383735 |
| LATS2 | large tumor suppressor kinase 2 | -0.0382785 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -0.0375151 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0373696 |
| PTMA | prothymosin, alpha | -0.0370376 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0370341 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0370263 |
| RAD51B | RAD51 paralog B | -0.036968 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0368241 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0363737 |
| RPS3 | ribosomal protein S3 | -0.0361798 |
| RPL32 | ribosomal protein L32 | -0.0358893 |
| WASF2 | WAS protein family, member 2 | -0.035851 |
| IGF2 | insulin-like growth factor 2 | -0.0357957 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0356499 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0356094 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0352621 |
| PHF20 | PHD finger protein 20 | -0.035132 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0347002 |
| RPS29 | ribosomal protein S29 | -0.0346729 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0345411 |
| ETV6 | ets variant 6 | -0.0338506 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0338276 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0337329 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.03356 |
| RYR3 | ryanodine receptor 3 | -0.0335144 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0331669 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0328742 |
| CENPF | centromere protein F, 350/400kDa | -0.0327968 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0327229 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0326856 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0326537 |
| AHNAK | AHNAK nucleoprotein | -0.032269 |
| SBF2 | SET binding factor 2 | -0.0321538 |
| MT2A | metallothionein 2A | -0.0316028 |
| RPL35A | ribosomal protein L35a | -0.0313764 |
| CPNE8 | copine VIII | -0.0311536 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0311475 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0310545 |
| RPL36A | ribosomal protein L36a | -0.0309555 |
| RIGI | RNA sensor RIG-I | -0.0307609 |
| THOC2 | THO complex 2 | -0.0306506 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0305862 |
| MAP4 | microtubule-associated protein 4 | -0.0302773 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0302648 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0300557 |
| MT1X | metallothionein 1X | -0.0299798 |
| RPS21 | ribosomal protein S21 | -0.0299395 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0298914 |
| TRIM56 | tripartite motif containing 56 | -0.0296632 |
| ZNF292 | zinc finger protein 292 | -0.0296593 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0296427 |
| ADAR | adenosine deaminase, RNA-specific | -0.0295409 |
| RGS17 | regulator of G-protein signaling 17 | -0.0295029 |
| RPS27A | ribosomal protein S27a | -0.0294669 |
| CDK17 | cyclin-dependent kinase 17 | -0.0294228 |
| CAVIN1 | caveolae associated protein 1 | -0.0294225 |
| RPL36 | ribosomal protein L36 | -0.0291824 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0288649 |
| DHFR | dihydrofolate reductase | -0.0286881 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0285913 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0285362 |
| TAGLN2 | transgelin 2 | -0.0283525 |
| CBX3 | chromobox homolog 3 | -0.0283295 |
| RPL12 | ribosomal protein L12 | -0.0282757 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.028205 |
