| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clobetasol propionate perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clobetasol propionate_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.193841 |
| MT2A | metallothionein 2A | 0.190684 |
| FN1 | fibronectin 1 | 0.135154 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.120986 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0844987 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0844443 |
| TOP1 | topoisomerase (DNA) I | 0.0797921 |
| AHNAK | AHNAK nucleoprotein | 0.0714017 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0685487 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0667483 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0543092 |
| HOMER2 | homer scaffolding protein 2 | 0.0511912 |
| FKBP5 | FK506 binding protein 5 | 0.0492048 |
| IL6ST | interleukin 6 signal transducer | 0.0457596 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0452403 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0446552 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0443801 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0443625 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0399248 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.039134 |
| RNF145 | ring finger protein 145 | 0.0387481 |
| ANXA2 | annexin A2 | 0.0381897 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0373031 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0366333 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0364897 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0363158 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0336322 |
| HMGB2 | high mobility group box 2 | 0.0328401 |
| CANX | calnexin | 0.0314961 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0314553 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0310984 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0305582 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | 0.0294662 |
| JAK1 | Janus kinase 1 | 0.0293987 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0289033 |
| NCKAP1 | NCK-associated protein 1 | 0.028528 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0284952 |
| USP3 | ubiquitin specific peptidase 3 | 0.0281802 |
| TFG | TRK-fused gene | 0.0281153 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0280889 |
| RYBP | RING1 and YY1 binding protein | 0.0279698 |
| RBM39 | RNA binding motif protein 39 | 0.0278715 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0278389 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0271263 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.026997 |
| PLEC | plectin | 0.0267491 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0265589 |
| MT1E | metallothionein 1E | 0.0263713 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0263523 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0262435 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0255909 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0255086 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0252412 |
| SDC4 | syndecan 4 | 0.0248305 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0245379 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0239275 |
| EGFR | epidermal growth factor receptor | 0.0237401 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0237384 |
| CLINT1 | clathrin interactor 1 | 0.0236532 |
| FCHO2 | FCH domain only 2 | 0.0236376 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0235349 |
| ANXA5 | annexin A5 | 0.0235011 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0230389 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0230081 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0229704 |
| RBM33 | RNA binding motif protein 33 | 0.022304 |
| LRRC1 | leucine rich repeat containing 1 | 0.0217211 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0216803 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.021479 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0213168 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0211315 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.021014 |
| STK24 | serine/threonine kinase 24 | 0.020888 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0206592 |
| APP | amyloid beta (A4) precursor protein | 0.0204234 |
| YAP1 | Yes-associated protein 1 | 0.0203796 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | 0.0201536 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0201496 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0199383 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0198375 |
| RLF | rearranged L-myc fusion | 0.019796 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0195027 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0194038 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0194007 |
| RPL7 | ribosomal protein L7 | 0.0191888 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0191553 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0190905 |
| ECT2 | epithelial cell transforming 2 | 0.0190367 |
| ZNF292 | zinc finger protein 292 | 0.0189835 |
| RYK | receptor-like tyrosine kinase | 0.0189549 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0188329 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0185035 |
| NUP58 | nucleoporin 58 | 0.0184184 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.018318 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0181432 |
| RASA2 | RAS p21 protein activator 2 | 0.0180851 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0180668 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0179177 |
| OLA1 | Obg-like ATPase 1 | 0.0177707 |
| EREG | epiregulin | 0.0177317 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.220504 |
| POTEF | POTE ankyrin domain family, member F | -0.193279 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.165469 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.14829 |
| PTMA | prothymosin, alpha | -0.129712 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.126797 |
| FBXO32 | F-box protein 32 | -0.120668 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.113634 |
| TMSB10 | thymosin beta 10 | -0.111511 |
| NDRG1 | N-myc downstream regulated 1 | -0.106332 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0853892 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0843957 |
| ACTG1 | actin gamma 1 | -0.0814757 |
| CSTB | cystatin B (stefin B) | -0.0786503 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0751845 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0742182 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0723165 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0705497 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0698221 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0645731 |
| HLA-B | major histocompatibility complex, class I, B | -0.0630259 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0623056 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0602516 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0552527 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0537746 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0520633 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0502257 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0497994 |
| HLA-A | major histocompatibility complex, class I, A | -0.0481532 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0461794 |
| RPL35A | ribosomal protein L35a | -0.045941 |
| MYO6 | myosin VI | -0.0453242 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0452118 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0451281 |
| DTNA | dystrobrevin, alpha | -0.0441957 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0437427 |
| TMSB4X | thymosin beta 4, X-linked | -0.0435078 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0434547 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0432921 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0431754 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0421832 |
| VIM | vimentin | -0.0421471 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0420136 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0420094 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0405861 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0399391 |
| TPM4 | tropomyosin 4 | -0.0388012 |
| VEGFA | vascular endothelial growth factor A | -0.0386633 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0377039 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0369716 |
| MX2 | MX dynamin-like GTPase 2 | -0.0361751 |
| MYO1E | myosin IE | -0.0360024 |
| RPLP2 | ribosomal protein, large, P2 | -0.0359219 |
| HMGA1 | high mobility group AT-hook 1 | -0.0356636 |
| ENO1 | enolase 1, (alpha) | -0.035647 |
| GNAS | GNAS complex locus | -0.0351716 |
| CLDN4 | claudin 4 | -0.0350636 |
| SQSTM1 | sequestosome 1 | -0.0340266 |
| RPS13 | ribosomal protein S13 | -0.0336503 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0336419 |
| TPI1 | triosephosphate isomerase 1 | -0.0335955 |
| CCND1 | cyclin D1 | -0.0335564 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0334519 |
| RNF213 | ring finger protein 213 | -0.0330593 |
| RPLP1 | ribosomal protein, large, P1 | -0.0330509 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0325607 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0323543 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0322367 |
| RPS19 | ribosomal protein S19 | -0.0319926 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0319039 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.031688 |
| RBM47 | RNA binding motif protein 47 | -0.0314648 |
| RPS8 | ribosomal protein S8 | -0.031382 |
| WASF2 | WAS protein family, member 2 | -0.0313705 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0312621 |
| KRT19 | keratin 19, type I | -0.0308178 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0306275 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0305712 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0305659 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0302847 |
| PKM | pyruvate kinase, muscle | -0.0302798 |
| MAP1B | microtubule-associated protein 1B | -0.0301954 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.030176 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.029932 |
| FAM3C | family with sequence similarity 3, member C | -0.0297308 |
| LMNA | lamin A/C | -0.0293082 |
| RPS6 | ribosomal protein S6 | -0.0286076 |
| MXD1 | MAX dimerization protein 1 | -0.028314 |
| RPL9 | ribosomal protein L9 | -0.0280242 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0279355 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0276899 |
| RPL37A | ribosomal protein L37a | -0.0275237 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0274929 |
| PGBD5 | piggyBac transposable element derived 5 | -0.0273079 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0271116 |
| RPS23 | ribosomal protein S23 | -0.0271082 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0268085 |
| H3-3B | H3.3 histone B | -0.0268026 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0265829 |
| DUSP10 | dual specificity phosphatase 10 | -0.0265554 |
