| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clobetasol propionate perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clobetasol propionate_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GDA | guanine deaminase | 0.232245 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.156989 |
| PM20D1 | peptidase M20 domain containing 1 | 0.13769 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0983814 |
| PDE10A | phosphodiesterase 10A | 0.0773066 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0759219 |
| SMYD3 | SET and MYND domain containing 3 | 0.0686589 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0600654 |
| TXNRD1 | thioredoxin reductase 1 | 0.0493443 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0491044 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0423684 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0407789 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0393708 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0388308 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0383908 |
| RTN1 | reticulon 1 | 0.0347672 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0344858 |
| NFIA | nuclear factor I/A | 0.0330069 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0323281 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | 0.030217 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0301231 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.029337 |
| FKBP5 | FK506 binding protein 5 | 0.0280796 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0271869 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.026963 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0265332 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0262807 |
| ENAH | enabled homolog (Drosophila) | 0.02372 |
| CAVIN2 | caveolae associated protein 2 | 0.0229576 |
| KYNU | kynureninase | 0.0226452 |
| EFNA5 | ephrin-A5 | 0.0213982 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0213756 |
| SDC2 | syndecan 2 | 0.0209698 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0206523 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | 0.0206391 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0203868 |
| PHF20 | PHD finger protein 20 | 0.0202085 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | 0.0196361 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0196065 |
| KIAA0825 | KIAA0825 | 0.0193342 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.0176219 |
| RPGR | retinitis pigmentosa GTPase regulator | 0.0174309 |
| CHML | choroideremia-like (Rab escort protein 2) | 0.0169125 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited | 0.0165335 |
| ETV1 | ets variant 1 | 0.0154869 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0154858 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0154706 |
| SAMD8 | sterile alpha motif domain containing 8 | 0.0152235 |
| ZBTB16 | zinc finger and BTB domain containing 16 | 0.0150046 |
| SLC15A5 | solute carrier family 15, member 5 | 0.0148744 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0145633 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0141544 |
| DCLK2 | doublecortin-like kinase 2 | 0.0137739 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | 0.0132571 |
| PHF14 | PHD finger protein 14 | 0.0130957 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0130859 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.0130551 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0129153 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0126637 |
| RNF115 | ring finger protein 115 | 0.0126318 |
| KCNG2 | potassium channel, voltage gated modifier subfamily G, member 2 | 0.0125705 |
| MAT2A | methionine adenosyltransferase II, alpha | 0.0125698 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.012428 |
| COL5A2 | collagen, type V, alpha 2 | 0.0123597 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0122768 |
| FNBP1L | formin binding protein 1-like | 0.011987 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0117959 |
| SCARA5 | scavenger receptor class A, member 5 | 0.0116569 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0115908 |
| OSMR | oncostatin M receptor | 0.0115195 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0114966 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0114328 |
| DNAH5 | dynein, axonemal, heavy chain 5 | 0.0112953 |
| HEATR1 | HEAT repeat containing 1 | 0.0111423 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0110367 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0108861 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0108773 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.0104573 |
| EXO1 | exonuclease 1 | 0.0104296 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0103356 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0101384 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0101242 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0100702 |
| MGST1 | microsomal glutathione S-transferase 1 | 0.01 |
| MFF | mitochondrial fission factor | 0.00997256 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0098819 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.00978183 |
| FAM222B | family with sequence similarity 222, member B | 0.00975133 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.00965424 |
| UTRN | utrophin | 0.00958063 |
| R3HDM1 | R3H domain containing 1 | 0.00946918 |
| ITGB8 | integrin, beta 8 | 0.00937091 |
| NFIB | nuclear factor I/B | 0.0093245 |
| FAM241A | family with sequence similarity 241 member A | 0.00931417 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.00914685 |
| LDLRAD3 | low density lipoprotein receptor class A domain containing 3 | 0.00913862 |
| DIAPH2 | diaphanous-related formin 2 | 0.0090548 |
| PYGB | phosphorylase, glycogen; brain | 0.00904686 |
| UCK2 | uridine-cytidine kinase 2 | 0.00897247 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | 0.00888271 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.203224 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.159277 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.146401 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.118139 |
| TMSB10 | thymosin beta 10 | -0.108699 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0806621 |
| VIM | vimentin | -0.0709895 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0708998 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0698947 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0692065 |
| ASPH | aspartate beta-hydroxylase | -0.0674773 |
| PTMA | prothymosin, alpha | -0.0669051 |
| CDH13 | cadherin 13 | -0.0649736 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0619365 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0611696 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0596908 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0585509 |
| RPS6 | ribosomal protein S6 | -0.056092 |
| RPLP1 | ribosomal protein, large, P1 | -0.0541748 |
| FTL | ferritin, light polypeptide | -0.0533236 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0512799 |
| MYOF | myoferlin | -0.0508515 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0497939 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.04867 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0484382 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0484116 |
| TGFBR1 | transforming growth factor, beta receptor 1 | -0.0479137 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0474672 |
| RPL23 | ribosomal protein L23 | -0.046997 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.046396 |
| SPAG9 | sperm associated antigen 9 | -0.0455599 |
| RPS8 | ribosomal protein S8 | -0.0453952 |
| RPL12 | ribosomal protein L12 | -0.0452742 |
| RPL26 | ribosomal protein L26 | -0.0452244 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0436705 |
| LSAMP | limbic system-associated membrane protein | -0.0436208 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0431299 |
| NDRG1 | N-myc downstream regulated 1 | -0.0430475 |
| MAP7 | microtubule-associated protein 7 | -0.0423215 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0416129 |
| RPL37A | ribosomal protein L37a | -0.0416109 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0414437 |
| RPS19 | ribosomal protein S19 | -0.0411297 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.040877 |
| RPS27A | ribosomal protein S27a | -0.0398101 |
| RPL35A | ribosomal protein L35a | -0.0392028 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0385891 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0373197 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0367835 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0364353 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0364118 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0363631 |
| RPL31 | ribosomal protein L31 | -0.0359729 |
| RPL19 | ribosomal protein L19 | -0.0354476 |
| RPS12 | ribosomal protein S12 | -0.0351045 |
| MCL1 | myeloid cell leukemia 1 | -0.0350799 |
| STC1 | stanniocalcin 1 | -0.0349203 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0345411 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0344137 |
| CANX | calnexin | -0.0340618 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0338421 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0338111 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0324876 |
| RPS3 | ribosomal protein S3 | -0.0321005 |
| UBC | ubiquitin C | -0.0320033 |
| PRELID2 | PRELI domain containing 2 | -0.0316239 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0316206 |
| B2M | beta-2-microglobulin | -0.0315353 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0312905 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0308918 |
| INHBA | inhibin, beta A | -0.0306815 |
| RPS24 | ribosomal protein S24 | -0.030491 |
| CTBP2 | C-terminal binding protein 2 | -0.0302281 |
| RPS27 | ribosomal protein S27 | -0.0301777 |
| PKM | pyruvate kinase, muscle | -0.030126 |
| RPS23 | ribosomal protein S23 | -0.0301205 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0299553 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0298279 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0298072 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0295803 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0294443 |
| ENO1 | enolase 1, (alpha) | -0.0293491 |
| NCKAP5 | NCK-associated protein 5 | -0.0292085 |
| FMNL2 | formin-like 2 | -0.0291149 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0289965 |
| GNAS | GNAS complex locus | -0.0285549 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0284355 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.0284022 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0280827 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0280012 |
| ACTG1 | actin gamma 1 | -0.0278843 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0273774 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0271912 |
| S100A10 | S100 calcium binding protein A10 | -0.026926 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.026817 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0266931 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0265165 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0264132 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0261289 |
| CTIF | CBP80/20-dependent translation initiation factor | -0.0261232 |
