| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clobetasol propionate perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clobetasol propionate_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | 0.172204 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.161803 |
| CADM2 | cell adhesion molecule 2 | 0.129663 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0974647 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0946313 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0943912 |
| NTM | neurotrimin | 0.0863607 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0732291 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0629044 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0555243 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0530073 |
| TENM3 | teneurin transmembrane protein 3 | 0.0529133 |
| ZNF292 | zinc finger protein 292 | 0.0503756 |
| COL5A2 | collagen, type V, alpha 2 | 0.0483856 |
| ITGAV | integrin, alpha V | 0.0473289 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0465936 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0464747 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0443192 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0436286 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0435993 |
| UTRN | utrophin | 0.0432258 |
| FOXP2 | forkhead box P2 | 0.0425861 |
| NPAS3 | neuronal PAS domain protein 3 | 0.0423822 |
| TOX | thymocyte selection-associated high mobility group box | 0.0420268 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0411845 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.04106 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0403831 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0395983 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0374269 |
| CDH19 | cadherin 19, type 2 | 0.0373266 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0360159 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0357165 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0351126 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0338811 |
| RBM39 | RNA binding motif protein 39 | 0.0337327 |
| JMJD1C | jumonji domain containing 1C | 0.0328722 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0313243 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.030444 |
| RYBP | RING1 and YY1 binding protein | 0.0298898 |
| YAP1 | Yes-associated protein 1 | 0.0294184 |
| FAM171B | family with sequence similarity 171, member B | 0.0289995 |
| DMD | dystrophin | 0.0289004 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0273729 |
| ECT2 | epithelial cell transforming 2 | 0.0271536 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0271265 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0269325 |
| LRRC4C | leucine rich repeat containing 4C | 0.0264006 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0259993 |
| ZNF608 | zinc finger protein 608 | 0.0256264 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.0254063 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0253885 |
| LRRN3 | leucine rich repeat neuronal 3 | 0.0246759 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0246064 |
| HDAC9 | histone deacetylase 9 | 0.0241929 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0240267 |
| PCDH9 | protocadherin 9 | 0.0239366 |
| PDGFC | platelet derived growth factor C | 0.0236573 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.02352 |
| LPIN2 | lipin 2 | 0.0232443 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0231697 |
| METAP2 | methionyl aminopeptidase 2 | 0.0230589 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | 0.0229234 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0228773 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0227398 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0225179 |
| ATF6 | activating transcription factor 6 | 0.0223944 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0223833 |
| RDX | radixin | 0.0223784 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0223043 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | 0.022284 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0219781 |
| USH2A | Usher syndrome 2A (autosomal recessive, mild) | 0.0216462 |
| UNC5C | unc-5 homolog C (C. elegans) | 0.0214605 |
| NFIA | nuclear factor I/A | 0.0213691 |
| MYO10 | myosin X | 0.0213427 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.0211727 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0211415 |
| WDR70 | WD repeat domain 70 | 0.0209937 |
| RBM20 | RNA binding motif protein 20 | 0.0209728 |
| FIGN | fidgetin | 0.0209386 |
| SHROOM3 | shroom family member 3 | 0.0209286 |
| PHF3 | PHD finger protein 3 | 0.0208374 |
| RLF | rearranged L-myc fusion | 0.0208239 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0207632 |
| ANK2 | ankyrin 2, neuronal | 0.0206355 |
| ATAD2B | ATPase family, AAA domain containing 2B | 0.0206081 |
| NCKAP1 | NCK-associated protein 1 | 0.0205605 |
| CLASP2 | cytoplasmic linker associated protein 2 | 0.0202144 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.0196894 |
| TRAK1 | trafficking protein, kinesin binding 1 | 0.0195353 |
| PLPP1 | phospholipid phosphatase 1 | 0.0195228 |
| WDR43 | WD repeat domain 43 | 0.0195003 |
| YME1L1 | YME1-like 1 ATPase | 0.019372 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0193477 |
| VWA8 | von Willebrand factor A domain containing 8 | 0.0193253 |
| MEIS2 | Meis homeobox 2 | 0.0193247 |
| PTGES2 | prostaglandin E synthase 2 | 0.0193003 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.01929 |
| TMEM64 | transmembrane protein 64 | 0.0191686 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0190738 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.158523 |
| TMSB10 | thymosin beta 10 | -0.13799 |
| PTMA | prothymosin, alpha | -0.110459 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.10126 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0812031 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0739468 |
| ACTG1 | actin gamma 1 | -0.0732011 |
| RPLP1 | ribosomal protein, large, P1 | -0.0691053 |
| RPS8 | ribosomal protein S8 | -0.0690461 |
| RPL35A | ribosomal protein L35a | -0.0642986 |
| GNAS | GNAS complex locus | -0.0629107 |
| RPS16 | ribosomal protein S16 | -0.05977 |
| RPL23 | ribosomal protein L23 | -0.058067 |
| RPS6 | ribosomal protein S6 | -0.0578833 |
| RPS12 | ribosomal protein S12 | -0.057878 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0576787 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0545004 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0519047 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0514487 |
| RPL19 | ribosomal protein L19 | -0.0505075 |
| POTEF | POTE ankyrin domain family, member F | -0.0502619 |
| RPL11 | ribosomal protein L11 | -0.0467992 |
| PFN1 | profilin 1 | -0.046633 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0461589 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0456779 |
| RPL37 | ribosomal protein L37 | -0.0455977 |
| FN1 | fibronectin 1 | -0.045329 |
| MKI67 | marker of proliferation Ki-67 | -0.0452695 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0449208 |
| RPS19 | ribosomal protein S19 | -0.0438194 |
| S100A10 | S100 calcium binding protein A10 | -0.0421337 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0420104 |
| RPS27A | ribosomal protein S27a | -0.0405829 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0397835 |
| RPS3 | ribosomal protein S3 | -0.0397658 |
| B2M | beta-2-microglobulin | -0.0393496 |
| RPL37A | ribosomal protein L37a | -0.0383792 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0373246 |
| GOLGA4 | golgin A4 | -0.0372043 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0366211 |
| RPS2 | ribosomal protein S2 | -0.0360091 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0351384 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0351353 |
| RPL12 | ribosomal protein L12 | -0.0350143 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0348977 |
| CENPF | centromere protein F, 350/400kDa | -0.034346 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0340351 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0339648 |
| PDCD5 | programmed cell death 5 | -0.0338627 |
| FTL | ferritin, light polypeptide | -0.0332408 |
| ENO1 | enolase 1, (alpha) | -0.0327467 |
| RPL34 | ribosomal protein L34 | -0.0325459 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0321588 |
| TMSB4X | thymosin beta 4, X-linked | -0.0321354 |
| MAP4 | microtubule-associated protein 4 | -0.0321173 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0318644 |
| S100A9 | S100 calcium binding protein A9 | -0.0317334 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0314127 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0311702 |
| RACK1 | receptor for activated C kinase 1 | -0.0304318 |
| YBX1 | Y box binding protein 1 | -0.0301992 |
| LDHA | lactate dehydrogenase A | -0.0301416 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0300179 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0293629 |
| H1-0 | H1.0 linker histone | -0.0293348 |
| HMGA1 | high mobility group AT-hook 1 | -0.0293059 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0289206 |
| PGK1 | phosphoglycerate kinase 1 | -0.0287987 |
| RPL9 | ribosomal protein L9 | -0.0285662 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0282785 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0282065 |
| RAI1 | retinoic acid induced 1 | -0.0281125 |
| RPLP2 | ribosomal protein, large, P2 | -0.027995 |
| ANXA1 | annexin A1 | -0.0279786 |
| THOC2 | THO complex 2 | -0.0279755 |
| RPL32 | ribosomal protein L32 | -0.0274638 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0272632 |
| PEG10 | paternally expressed 10 | -0.0270047 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0265565 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.026528 |
| MT2A | metallothionein 2A | -0.0264812 |
| RPS5 | ribosomal protein S5 | -0.026481 |
| GPC6 | glypican 6 | -0.0264427 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0263792 |
| NRG1 | neuregulin 1 | -0.0261394 |
| RPL5 | ribosomal protein L5 | -0.0260424 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0259028 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0257863 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.025785 |
| RPS27 | ribosomal protein S27 | -0.0257737 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0256916 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0256765 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0254222 |
| CDK6 | cyclin-dependent kinase 6 | -0.0254209 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0252921 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0251437 |
| CALR | calreticulin | -0.0251002 |
| RPL26 | ribosomal protein L26 | -0.0249577 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -0.0248514 |
| RPS29 | ribosomal protein S29 | -0.0247301 |
