| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clobetasol propionate perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clobetasol propionate_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BIRC3 | baculoviral IAP repeat containing 3 | 0.124268 |
| FKBP5 | FK506 binding protein 5 | 0.107304 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.104618 |
| MT2A | metallothionein 2A | 0.0991848 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0890221 |
| AHNAK | AHNAK nucleoprotein | 0.0736393 |
| EFNA5 | ephrin-A5 | 0.0713249 |
| C3 | complement component 3 | 0.0636876 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0565164 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.056379 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0553328 |
| BCL2L1 | BCL2-like 1 | 0.053824 |
| TGM2 | transglutaminase 2 | 0.0519984 |
| LDHA | lactate dehydrogenase A | 0.0516171 |
| KRT7 | keratin 7, type II | 0.0506478 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0504657 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0497583 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0484441 |
| NFIB | nuclear factor I/B | 0.0479749 |
| TXNIP | thioredoxin interacting protein | 0.0472767 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0458914 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0436589 |
| FLNB | filamin B, beta | 0.0436025 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0430144 |
| TOP1 | topoisomerase (DNA) I | 0.042251 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0418907 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0414123 |
| MKI67 | marker of proliferation Ki-67 | 0.041018 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.0407593 |
| WWC1 | WW and C2 domain containing 1 | 0.0405153 |
| IL6ST | interleukin 6 signal transducer | 0.0393077 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0388118 |
| POTEF | POTE ankyrin domain family, member F | 0.0369287 |
| LAMA4 | laminin, alpha 4 | 0.0364932 |
| TSC22D2 | TSC22 domain family, member 2 | 0.036191 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0352807 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0351672 |
| MT1X | metallothionein 1X | 0.0351534 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0348489 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0347657 |
| CCND3 | cyclin D3 | 0.0345755 |
| IRS2 | insulin receptor substrate 2 | 0.034401 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0343437 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0337583 |
| ZNF148 | zinc finger protein 148 | 0.0328756 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.0324123 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0321929 |
| STK24 | serine/threonine kinase 24 | 0.0321059 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0317839 |
| HOMER2 | homer scaffolding protein 2 | 0.0312774 |
| DIAPH3 | diaphanous-related formin 3 | 0.0312053 |
| RTN4 | reticulon 4 | 0.0311016 |
| ECT2 | epithelial cell transforming 2 | 0.0309824 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0308875 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0305569 |
| TFCP2L1 | transcription factor CP2-like 1 | 0.0305204 |
| GOLGA4 | golgin A4 | 0.0299942 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0293469 |
| LDLRAD3 | low density lipoprotein receptor class A domain containing 3 | 0.0293395 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0291928 |
| ATP11B | ATPase, class VI, type 11B | 0.0291564 |
| TNS4 | tensin 4 | 0.0289063 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0288793 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0282229 |
| HIPK3 | homeodomain interacting protein kinase 3 | 0.0281163 |
| RDX | radixin | 0.0280899 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0279408 |
| SPIDR | scaffolding protein involved in DNA repair | 0.027556 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0270752 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0268444 |
| CCNY | cyclin Y | 0.0263406 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0256126 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0255899 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0248599 |
| GPHN | gephyrin | 0.0245303 |
| DSPP | dentin sialophosphoprotein | 0.0243467 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0239747 |
| PCBP2 | poly(rC) binding protein 2 | 0.0235605 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0235117 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.023461 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0231581 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0230482 |
| FAR1 | fatty acyl CoA reductase 1 | 0.022968 |
| CCNL1 | cyclin L1 | 0.0229437 |
| RBM25 | RNA binding motif protein 25 | 0.0226182 |
| PLEKHA7 | pleckstrin homology domain containing, family A member 7 | 0.0224905 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.0224094 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0223265 |
| EGFR | epidermal growth factor receptor | 0.0222494 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.022213 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0221899 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0221372 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0220471 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0217227 |
| SHROOM3 | shroom family member 3 | 0.0216364 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0214588 |
| DIAPH1 | diaphanous-related formin 1 | 0.0213892 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0213085 |
| ATP13A3 | ATPase type 13A3 | 0.0211432 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.0211086 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.150177 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.122762 |
| INTS6 | integrator complex subunit 6 | -0.11703 |
| PTMA | prothymosin, alpha | -0.0983439 |
| RNF213 | ring finger protein 213 | -0.0963099 |
| MYO6 | myosin VI | -0.0952667 |
| LAMB3 | laminin, beta 3 | -0.0945128 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0940258 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0937901 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0917959 |
| FN1 | fibronectin 1 | -0.0905701 |
| SQSTM1 | sequestosome 1 | -0.0901881 |
| LMO7 | LIM domain 7 | -0.0818986 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.080426 |
| TMSB4X | thymosin beta 4, X-linked | -0.0776102 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0748831 |
| PLSCR1 | phospholipid scramblase 1 | -0.0714004 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0695164 |
| HDAC9 | histone deacetylase 9 | -0.0694468 |
| CD2AP | CD2-associated protein | -0.0690967 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0681708 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0679274 |
| ACTG1 | actin gamma 1 | -0.0670271 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0632565 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0622153 |
| RIGI | RNA sensor RIG-I | -0.0621076 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0614686 |
| HLA-B | major histocompatibility complex, class I, B | -0.0609176 |
| MYO1E | myosin IE | -0.0605727 |
| LAMC2 | laminin, gamma 2 | -0.0601999 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0598691 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0588288 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0586015 |
| ETV6 | ets variant 6 | -0.0572034 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0571153 |
| SYT14 | synaptotagmin XIV | -0.0549134 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.053248 |
| RPL35A | ribosomal protein L35a | -0.0532457 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0527111 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0513944 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0513642 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0511584 |
| ANKRD10 | ankyrin repeat domain 10 | -0.048761 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0487586 |
| HLA-C | major histocompatibility complex, class I, C | -0.0481595 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0479702 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | -0.0477399 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0477364 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0476466 |
| TMSB10 | thymosin beta 10 | -0.0469946 |
| SP100 | SP100 nuclear antigen | -0.046526 |
| MYO5B | myosin VB | -0.046143 |
| SVIL | supervillin | -0.0458191 |
| MUC4 | mucin 4, cell surface associated | -0.0456163 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0451175 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0444375 |
| SMAD3 | SMAD family member 3 | -0.044354 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0421875 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0421261 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0419041 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0415637 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0413255 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0412383 |
| CD47 | CD47 molecule | -0.0412073 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0411793 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0410417 |
| RUNX1 | runt-related transcription factor 1 | -0.0410002 |
| HLA-E | major histocompatibility complex, class I, E | -0.0405192 |
| GNAS | GNAS complex locus | -0.0402301 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0378043 |
| AFDN | afadin, adherens junction formation factor | -0.0373732 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0371945 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.036874 |
| NDRG1 | N-myc downstream regulated 1 | -0.0360891 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0355338 |
| MX1 | MX dynamin-like GTPase 1 | -0.0353317 |
| MEF2A | myocyte enhancer factor 2A | -0.0349673 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0343497 |
| INHBA | inhibin, beta A | -0.0340232 |
| KYNU | kynureninase | -0.0331728 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | -0.0330755 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0329039 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0328987 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0327872 |
| PLAU | plasminogen activator, urokinase | -0.0316979 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0316937 |
| ERBIN | erbb2 interacting protein | -0.031509 |
| CLDN1 | claudin 1 | -0.0305626 |
| MUC20 | mucin 20, cell surface associated | -0.0305594 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.03055 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0304219 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0303125 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0300021 |
| IFI44 | interferon-induced protein 44 | -0.0298075 |
| FOXO3 | forkhead box O3 | -0.0297161 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0296599 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0295442 |
| RAP2B | RAP2B, member of RAS oncogene family | -0.0294844 |
| EMP1 | epithelial membrane protein 1 | -0.0291971 |
| RPL34 | ribosomal protein L34 | -0.0289078 |
