| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clobetasol propionate perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clobetasol propionate_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.122463 |
| ZNF438 | zinc finger protein 438 | 0.114709 |
| HDAC9 | histone deacetylase 9 | 0.0910253 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0873931 |
| FRMD6 | FERM domain containing 6 | 0.0779035 |
| HMGA2 | high mobility group AT-hook 2 | 0.0466788 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0449146 |
| NAV3 | neuron navigator 3 | 0.0437214 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0433319 |
| NABP1 | nucleic acid binding protein 1 | 0.0408091 |
| EGR1 | early growth response 1 | 0.0380796 |
| RPL7 | ribosomal protein L7 | 0.036808 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0365494 |
| INTS6 | integrator complex subunit 6 | 0.0328647 |
| CALR | calreticulin | 0.0304628 |
| TTR | transthyretin | 0.0303711 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.030087 |
| FRMD4A | FERM domain containing 4A | 0.02999 |
| EXOC4 | exocyst complex component 4 | 0.0299177 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0290512 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0285386 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0272519 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.0270509 |
| BNC2 | basonuclin 2 | 0.0266096 |
| CANX | calnexin | 0.0261801 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0244149 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0243406 |
| NAV2 | neuron navigator 2 | 0.0241384 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0239035 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0235201 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0234903 |
| PCNX4 | pecanex 4 | 0.0228094 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 0.0224542 |
| PHF3 | PHD finger protein 3 | 0.0211238 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0210805 |
| PGK1 | phosphoglycerate kinase 1 | 0.0208778 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0208054 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0190378 |
| FLNA | filamin A, alpha | 0.0187222 |
| FHIT | fragile histidine triad | 0.0187053 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0186101 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0184724 |
| CUTC | cutC copper transporter | 0.0183492 |
| SQSTM1 | sequestosome 1 | 0.0178993 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0178095 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0172689 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0172219 |
| HLA-A | major histocompatibility complex, class I, A | 0.0169634 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0166271 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0163681 |
| MYRFL | myelin regulatory factor-like | 0.0163672 |
| AEBP2 | AE binding protein 2 | 0.0160882 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.0160074 |
| DGKI | diacylglycerol kinase, iota | 0.0158907 |
| MSI2 | musashi RNA-binding protein 2 | 0.0158788 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.015471 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 | 0.0150714 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0148858 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | 0.0148748 |
| CAST | calpastatin | 0.0148027 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.0146961 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0145838 |
| FNIP1 | folliculin interacting protein 1 | 0.0145613 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0144508 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0144401 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 | 0.0144302 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0143397 |
| CALD1 | caldesmon 1 | 0.0141681 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0140019 |
| RPL35A | ribosomal protein L35a | 0.013991 |
| TPM4 | tropomyosin 4 | 0.0136136 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0135943 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0135923 |
| GOLGB1 | golgin B1 | 0.0135888 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0135545 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0133777 |
| CTBP2 | C-terminal binding protein 2 | 0.0132614 |
| NOP2 | NOP2 nucleolar protein | 0.0130982 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0129189 |
| TENM3 | teneurin transmembrane protein 3 | 0.0128069 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0127065 |
| SGMS2 | sphingomyelin synthase 2 | 0.0126354 |
| LARP1B | La ribonucleoprotein domain family, member 1B | 0.0125363 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0125204 |
| MSH4 | mutS homolog 4 | 0.0124859 |
| EMP1 | epithelial membrane protein 1 | 0.0124326 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0123828 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0123709 |
| ZNF407 | zinc finger protein 407 | 0.0122739 |
| MLEC | malectin | 0.0122432 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | 0.0122375 |
| GPATCH2L | G patch domain containing 2-like | 0.0122042 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0120677 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0120577 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0120157 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0119976 |
| RB1 | retinoblastoma 1 | 0.0119453 |
| ERCC1 | excision repair cross-complementation group 1 | 0.0119056 |
| CLEC11A | C-type lectin domain family 11, member A | 0.0118943 |
| ALKBH5 | AlkB family member 5, RNA demethylase | 0.0116208 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.143821 |
| ACTG1 | actin gamma 1 | -0.126605 |
| RPS2 | ribosomal protein S2 | -0.0988508 |
| RPS6 | ribosomal protein S6 | -0.0787285 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0768657 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0764174 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0733937 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0674844 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0637903 |
| STC1 | stanniocalcin 1 | -0.0591402 |
| RBM39 | RNA binding motif protein 39 | -0.058753 |
| POTEF | POTE ankyrin domain family, member F | -0.05523 |
| RPL7A | ribosomal protein L7a | -0.0529519 |
| PTMA | prothymosin, alpha | -0.0526037 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0523914 |
| PTK2 | protein tyrosine kinase 2 | -0.0523127 |
| RPLP2 | ribosomal protein, large, P2 | -0.0486032 |
| JMJD1C | jumonji domain containing 1C | -0.0483706 |
| RPS12 | ribosomal protein S12 | -0.0479102 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0474233 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0460291 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0452447 |
| TPD52 | tumor protein D52 | -0.0436035 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0421058 |
| RLF | rearranged L-myc fusion | -0.0418087 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0415731 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0407994 |
| SET | SET nuclear proto-oncogene | -0.0401816 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0392112 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0388306 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0388058 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0386959 |
| CDK17 | cyclin-dependent kinase 17 | -0.0379159 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0376279 |
| NDRG1 | N-myc downstream regulated 1 | -0.0375431 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0375322 |
| RASA2 | RAS p21 protein activator 2 | -0.0370455 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0368698 |
| RPS3 | ribosomal protein S3 | -0.036685 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0366763 |
| RPL37A | ribosomal protein L37a | -0.0363521 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0361188 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0358623 |
| SEPTIN7 | septin 7 | -0.0351834 |
| CAPRIN2 | caprin family member 2 | -0.0346487 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0341875 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0339644 |
| RBM25 | RNA binding motif protein 25 | -0.0338335 |
| RPLP1 | ribosomal protein, large, P1 | -0.0331641 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0331609 |
| WDR43 | WD repeat domain 43 | -0.0331105 |
| RUNX1 | runt-related transcription factor 1 | -0.0330974 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0330857 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0330706 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.032292 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | -0.0322465 |
| TMSB10 | thymosin beta 10 | -0.0322055 |
| RPS19 | ribosomal protein S19 | -0.0319877 |
| USP3 | ubiquitin specific peptidase 3 | -0.031951 |
| RPS21 | ribosomal protein S21 | -0.0317427 |
| RPL9 | ribosomal protein L9 | -0.0315049 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0315033 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0314304 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0314058 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.031372 |
| GNAS | GNAS complex locus | -0.0313448 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.031325 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0313022 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0311301 |
| PRRC2C | proline-rich coiled-coil 2C | -0.031007 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0304215 |
| USP34 | ubiquitin specific peptidase 34 | -0.030108 |
| NCKAP1 | NCK-associated protein 1 | -0.0298619 |
| MATR3 | matrin 3 | -0.0298052 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0292005 |
| CTTNBP2NL | CTTNBP2 N-terminal like | -0.0289159 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0287122 |
| ZNF292 | zinc finger protein 292 | -0.0286882 |
| CD44 | CD44 molecule (Indian blood group) | -0.0284589 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0281554 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0277716 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0276824 |
| SRPK2 | SRSF protein kinase 2 | -0.0276246 |
| MYO9B | myosin IXB | -0.0276072 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0274001 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0273568 |
| RPS8 | ribosomal protein S8 | -0.0270638 |
| RPL35 | ribosomal protein L35 | -0.0269838 |
| RNF24 | ring finger protein 24 | -0.0268695 |
| YEATS2 | YEATS domain containing 2 | -0.026865 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0267378 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0266175 |
| RPL19 | ribosomal protein L19 | -0.0260598 |
| SPAG9 | sperm associated antigen 9 | -0.025938 |
| GPHN | gephyrin | -0.0256015 |
| RECQL | RecQ helicase-like | -0.0255893 |
| SBF2 | SET binding factor 2 | -0.0255616 |
| FUBP3 | far upstream element (FUSE) binding protein 3 | -0.0255213 |
| RPS24 | ribosomal protein S24 | -0.0254012 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0251604 |
