| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clobetasol propionate perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clobetasol propionate_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.213463 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0926387 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0823845 |
| NAV2 | neuron navigator 2 | 0.075935 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0748939 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0679033 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0613502 |
| SH3RF3 | SH3 domain containing ring finger 3 | 0.0514719 |
| HMGA2 | high mobility group AT-hook 2 | 0.049784 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0486983 |
| TOP1 | topoisomerase (DNA) I | 0.0469691 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0463965 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0410215 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0384698 |
| MT1E | metallothionein 1E | 0.0376868 |
| HIP1 | huntingtin interacting protein 1 | 0.0348815 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0345642 |
| CD109 | CD109 molecule | 0.0345067 |
| MT1X | metallothionein 1X | 0.0327759 |
| MYO1B | myosin IB | 0.0311551 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0302161 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0299052 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0291352 |
| FAM13A | family with sequence similarity 13, member A | 0.0285847 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0274085 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0268331 |
| CENPF | centromere protein F, 350/400kDa | 0.0254652 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0252002 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.024711 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0245652 |
| TGM2 | transglutaminase 2 | 0.0239528 |
| JPH2 | junctophilin 2 | 0.0237993 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0228357 |
| RBM39 | RNA binding motif protein 39 | 0.0218595 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.0209682 |
| LAMB1 | laminin, beta 1 | 0.0205511 |
| PCBP3 | poly(rC) binding protein 3 | 0.0205263 |
| LOX | lysyl oxidase | 0.0199155 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0198998 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0194839 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0190754 |
| TRAM2 | translocation associated membrane protein 2 | 0.0189911 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0187316 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0186345 |
| YEATS2 | YEATS domain containing 2 | 0.0185373 |
| SNED1 | sushi, nidogen and EGF-like domains 1 | 0.0180055 |
| SETD5 | SET domain containing 5 | 0.0179667 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0166391 |
| DIAPH3 | diaphanous-related formin 3 | 0.0165994 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0162528 |
| TSC22D3 | TSC22 domain family, member 3 | 0.0162016 |
| TFG | TRK-fused gene | 0.0160783 |
| FOXO3 | forkhead box O3 | 0.0156742 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.015403 |
| CACNA1C | calcium channel, voltage-dependent, L type, alpha 1C subunit | 0.0153702 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0150655 |
| LPAR1 | lysophosphatidic acid receptor 1 | 0.0146406 |
| FKBP5 | FK506 binding protein 5 | 0.0143518 |
| ZNF292 | zinc finger protein 292 | 0.0143511 |
| PER1 | period circadian clock 1 | 0.0142716 |
| OGA | O-GlcNAcase | 0.0141983 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0141172 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0140936 |
| FN1 | fibronectin 1 | 0.0140334 |
| DNER | delta/notch-like EGF repeat containing | 0.0139007 |
| CDK19 | cyclin-dependent kinase 19 | 0.0137862 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0135823 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.0135524 |
| XPO1 | exportin 1 | 0.0135331 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0131659 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0130505 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0130251 |
| FOXO1 | forkhead box O1 | 0.012976 |
| ZNF148 | zinc finger protein 148 | 0.0129558 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0126703 |
| CCN4 | cellular communication network factor 4 | 0.0126288 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0124922 |
| TMEM39A | transmembrane protein 39A | 0.0123648 |
| ANGPTL4 | angiopoietin-like 4 | 0.0123377 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.0122749 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.0122123 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.012132 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0120498 |
| HELZ | helicase with zinc finger | 0.0120438 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0120289 |
| DAAM2 | dishevelled associated activator of morphogenesis 2 | 0.0118876 |
| SNX13 | sorting nexin 13 | 0.0118762 |
| FNIP1 | folliculin interacting protein 1 | 0.0118751 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0118639 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | 0.0118268 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0117876 |
| CRLS1 | cardiolipin synthase 1 | 0.0116206 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.011606 |
| TPX2 | TPX2, microtubule-associated | 0.0114853 |
| NUP58 | nucleoporin 58 | 0.0111618 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0110914 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 | 0.0110354 |
| ECT2 | epithelial cell transforming 2 | 0.0110322 |
| ZNF451 | zinc finger protein 451 | 0.01093 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0109041 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.344592 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.165399 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.162684 |
| B2M | beta-2-microglobulin | -0.16245 |
| STC1 | stanniocalcin 1 | -0.152097 |
| HLA-B | major histocompatibility complex, class I, B | -0.146793 |
| COL1A2 | collagen, type I, alpha 2 | -0.141629 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.127742 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.11917 |
| COL1A1 | collagen, type I, alpha 1 | -0.110946 |
| FRMD4A | FERM domain containing 4A | -0.103519 |
| FTL | ferritin, light polypeptide | -0.102158 |
| NDRG1 | N-myc downstream regulated 1 | -0.101854 |
| CD44 | CD44 molecule (Indian blood group) | -0.0948749 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0944817 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0901884 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0743681 |
| TMSB10 | thymosin beta 10 | -0.0719056 |
| INHBA | inhibin, beta A | -0.0717557 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0670424 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0669655 |
| PTMA | prothymosin, alpha | -0.0648997 |
| COL6A2 | collagen, type VI, alpha 2 | -0.064719 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0643556 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0637073 |
| CDH13 | cadherin 13 | -0.0600559 |
| TPM1 | tropomyosin 1 (alpha) | -0.05878 |
| SP100 | SP100 nuclear antigen | -0.057074 |
| NAV1 | neuron navigator 1 | -0.0569731 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0568838 |
| POTEF | POTE ankyrin domain family, member F | -0.0560572 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0556258 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0550998 |
| LOXL2 | lysyl oxidase-like 2 | -0.0550054 |
| HLA-A | major histocompatibility complex, class I, A | -0.0541825 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0515338 |
| NRP1 | neuropilin 1 | -0.0513854 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0507289 |
| IER3 | immediate early response 3 | -0.0504748 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.049932 |
| ENO1 | enolase 1, (alpha) | -0.0486024 |
| TPM4 | tropomyosin 4 | -0.0481914 |
| IL1B | interleukin 1, beta | -0.0466771 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0466337 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0461026 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0455351 |
| EML5 | echinoderm microtubule associated protein like 5 | -0.0453655 |
| RPLP1 | ribosomal protein, large, P1 | -0.0437487 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | -0.0433185 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0424268 |
| EGR1 | early growth response 1 | -0.0422361 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0422095 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0422012 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.041285 |
| TNNC1 | troponin C type 1 (slow) | -0.039972 |
| PKM | pyruvate kinase, muscle | -0.0399395 |
| RPS6 | ribosomal protein S6 | -0.039814 |
| CALR | calreticulin | -0.0394982 |
| TMEM178B | transmembrane protein 178B | -0.0394089 |
| HDAC9 | histone deacetylase 9 | -0.0393719 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.039214 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0391691 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0386087 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0374435 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.037246 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0367344 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0362652 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0361361 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0359803 |
| HLA-C | major histocompatibility complex, class I, C | -0.0357943 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0355824 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0354961 |
| IFI44L | interferon-induced protein 44-like | -0.0351549 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0347981 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0347488 |
| COL5A3 | collagen, type V, alpha 3 | -0.0339853 |
| ACTG1 | actin gamma 1 | -0.0339672 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0336666 |
| S100A6 | S100 calcium binding protein A6 | -0.0335661 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0329383 |
| GNAS | GNAS complex locus | -0.0324018 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0319783 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0318793 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0316815 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0314719 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0314541 |
| MX2 | MX dynamin-like GTPase 2 | -0.0311788 |
| RIGI | RNA sensor RIG-I | -0.0307222 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0306034 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0302155 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0301162 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0300166 |
| RPL35A | ribosomal protein L35a | -0.0299263 |
| PMP22 | peripheral myelin protein 22 | -0.0298087 |
| CADM1 | cell adhesion molecule 1 | -0.0294471 |
| MX1 | MX dynamin-like GTPase 1 | -0.0294387 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0294016 |
| HLA-E | major histocompatibility complex, class I, E | -0.0292491 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0291088 |
| MMP2 | matrix metallopeptidase 2 | -0.0290804 |