| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clobetasol propionate perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clobetasol propionate_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.152675 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.139179 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0951756 |
| EGFR | epidermal growth factor receptor | 0.093604 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0925459 |
| RTN4 | reticulon 4 | 0.0894424 |
| PDGFC | platelet derived growth factor C | 0.0779143 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0753147 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0718987 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0682989 |
| TXNRD1 | thioredoxin reductase 1 | 0.0673004 |
| TJP1 | tight junction protein 1 | 0.0637669 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0616045 |
| ANK2 | ankyrin 2, neuronal | 0.0592486 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0585383 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0574311 |
| RBM39 | RNA binding motif protein 39 | 0.0563623 |
| EZR | ezrin | 0.0562398 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0559705 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0539125 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0538836 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0531457 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0529959 |
| JMJD1C | jumonji domain containing 1C | 0.0521928 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0479439 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0446011 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0441768 |
| GOLGA4 | golgin A4 | 0.0440732 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0429263 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0422659 |
| QKI | QKI, KH domain containing, RNA binding | 0.040737 |
| ZNF292 | zinc finger protein 292 | 0.0406137 |
| NCKAP1 | NCK-associated protein 1 | 0.0403841 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0394429 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0393549 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0392933 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0389758 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0387451 |
| TFG | TRK-fused gene | 0.0383018 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0371846 |
| ATP9B | ATPase, class II, type 9B | 0.0369759 |
| ECT2 | epithelial cell transforming 2 | 0.0367476 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0366872 |
| COG5 | component of oligomeric golgi complex 5 | 0.0364592 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0364002 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.036306 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0360053 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0359718 |
| ZNF608 | zinc finger protein 608 | 0.035891 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0357541 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0349489 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0348292 |
| CDC73 | cell division cycle 73 | 0.0344862 |
| EVI5 | ecotropic viral integration site 5 | 0.0344851 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0339245 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0339148 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0337459 |
| LDHA | lactate dehydrogenase A | 0.0333824 |
| FNIP1 | folliculin interacting protein 1 | 0.0333812 |
| TMEM41B | transmembrane protein 41B | 0.0328214 |
| NBAS | neuroblastoma amplified sequence | 0.0327733 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0325778 |
| TMEM135 | transmembrane protein 135 | 0.0323316 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0323224 |
| MEF2A | myocyte enhancer factor 2A | 0.0322169 |
| CLTC | clathrin, heavy chain (Hc) | 0.0321518 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0318717 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0318228 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0315788 |
| NUP58 | nucleoporin 58 | 0.0303987 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0303431 |
| COG6 | component of oligomeric golgi complex 6 | 0.0300981 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0299924 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.029651 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0295594 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0295305 |
| CLIC4 | chloride intracellular channel 4 | 0.0294234 |
| VMP1 | vacuole membrane protein 1 | 0.0290514 |
| SETD5 | SET domain containing 5 | 0.0290451 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0289475 |
| CCNL1 | cyclin L1 | 0.0287697 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0285359 |
| FLNB | filamin B, beta | 0.0281199 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0281043 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0280943 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0279455 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0278521 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.027814 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0276223 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0274812 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0273998 |
| PTK2 | protein tyrosine kinase 2 | 0.0272544 |
| SGMS1 | sphingomyelin synthase 1 | 0.0269534 |
| ZNF644 | zinc finger protein 644 | 0.0266563 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0266438 |
| RHOA | ras homolog family member A | 0.0266414 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0266366 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0265947 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0265826 |
| RNF145 | ring finger protein 145 | 0.0265376 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.263982 |
| BMP10 | bone morphogenetic protein 10 | -0.105539 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0938052 |
| RPL35A | ribosomal protein L35a | -0.0842815 |
| MKI67 | marker of proliferation Ki-67 | -0.0766288 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0710783 |
| RPS6 | ribosomal protein S6 | -0.0703496 |
| RPS8 | ribosomal protein S8 | -0.0649686 |
| NAV2 | neuron navigator 2 | -0.0635906 |
| ACTG1 | actin gamma 1 | -0.0605717 |
| RPL19 | ribosomal protein L19 | -0.0565965 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0562054 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0519625 |
| RPLP1 | ribosomal protein, large, P1 | -0.0515858 |
| CENPF | centromere protein F, 350/400kDa | -0.0471244 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0465783 |
| CCND1 | cyclin D1 | -0.0461738 |
| RPL34 | ribosomal protein L34 | -0.0460934 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0459755 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0458579 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0441254 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0420935 |
| RPLP0 | ribosomal protein, large, P0 | -0.0404387 |
| BMP2K | BMP2 inducible kinase | -0.0395628 |
| S100A4 | S100 calcium binding protein A4 | -0.0392709 |
| RPS3 | ribosomal protein S3 | -0.0383315 |
| RPS27A | ribosomal protein S27a | -0.0381697 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0373445 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0369689 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0367599 |
| RPS19 | ribosomal protein S19 | -0.0367117 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0366831 |
| RPL37A | ribosomal protein L37a | -0.0365802 |
| DIAPH3 | diaphanous-related formin 3 | -0.0364481 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0361608 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0346595 |
| RPLP2 | ribosomal protein, large, P2 | -0.0342519 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.034137 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0339913 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0333397 |
| RPL11 | ribosomal protein L11 | -0.0328815 |
| RPL36 | ribosomal protein L36 | -0.0327095 |
| RPS12 | ribosomal protein S12 | -0.0325569 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0323841 |
| RPS13 | ribosomal protein S13 | -0.0316671 |
| GNAS | GNAS complex locus | -0.0316068 |
| MYL12B | myosin, light chain 12B, regulatory | -0.030997 |
| HJURP | Holliday junction recognition protein | -0.0304454 |
| RPL31 | ribosomal protein L31 | -0.0303 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0302626 |
| KIF5B | kinesin family member 5B | -0.0301984 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0291461 |
| RPL38 | ribosomal protein L38 | -0.0287435 |
| RPL26 | ribosomal protein L26 | -0.027865 |
| RPL23 | ribosomal protein L23 | -0.0277789 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0277215 |
| MT2A | metallothionein 2A | -0.0270247 |
| RPL12 | ribosomal protein L12 | -0.0267205 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0264915 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.026311 |
| GSE1 | Gse1 coiled-coil protein | -0.0260101 |
| RPL7A | ribosomal protein L7a | -0.0255836 |
| RPL9 | ribosomal protein L9 | -0.0252409 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.0251902 |
| RPL13A | ribosomal protein L13a | -0.0249382 |
| MYO5C | myosin VC | -0.0245256 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0244204 |
| CUX1 | cut-like homeobox 1 | -0.0242965 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.024217 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0240723 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.024066 |
| S100A9 | S100 calcium binding protein A9 | -0.023914 |
| B2M | beta-2-microglobulin | -0.0235645 |
| RPS27 | ribosomal protein S27 | -0.0234439 |
| HMGB1 | high mobility group box 1 | -0.0231836 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0227932 |
| TPI1 | triosephosphate isomerase 1 | -0.022738 |
| RPL28 | ribosomal protein L28 | -0.022707 |
| BCOR | BCL6 corepressor | -0.022388 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0220679 |
| RIGI | RNA sensor RIG-I | -0.0220333 |
| RPS24 | ribosomal protein S24 | -0.0218572 |
| RACK1 | receptor for activated C kinase 1 | -0.0217928 |
| RPL8 | ribosomal protein L8 | -0.0217447 |
| TMSB10 | thymosin beta 10 | -0.0217202 |
| SMC3 | structural maintenance of chromosomes 3 | -0.021685 |
| DEK | DEK proto-oncogene | -0.0216657 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0216642 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0215432 |
| TPX2 | TPX2, microtubule-associated | -0.0214885 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0211217 |
| FTL | ferritin, light polypeptide | -0.0210933 |
| RPS11 | ribosomal protein S11 | -0.0206062 |
| EMP3 | epithelial membrane protein 3 | -0.0201504 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0200212 |
| RRBP1 | ribosome binding protein 1 | -0.0198823 |
| TMSB4X | thymosin beta 4, X-linked | -0.0198658 |
| PRC1 | protein regulator of cytokinesis 1 | -0.0198032 |
| HLA-B | major histocompatibility complex, class I, B | -0.0196196 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0195528 |
