| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clobetasol propionate perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clobetasol propionate_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCBP2 | poly(rC) binding protein 2 | 0.058564 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0523459 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0435515 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0428049 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0390523 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0381714 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0376146 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0360926 |
| PTK2 | protein tyrosine kinase 2 | 0.0360174 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0354514 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0340971 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0334895 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0332785 |
| TMF1 | TATA element modulatory factor 1 | 0.032778 |
| MYO1E | myosin IE | 0.0321154 |
| RSF1 | remodeling and spacing factor 1 | 0.0319369 |
| SETD5 | SET domain containing 5 | 0.0309065 |
| RCOR1 | REST corepressor 1 | 0.0301816 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0299466 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0294746 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0291398 |
| COPA | coatomer protein complex, subunit alpha | 0.0285493 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0283011 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0282099 |
| OXSR1 | oxidative stress responsive 1 | 0.028092 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0273853 |
| NEBL | nebulette | 0.0270065 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0269963 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0267713 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0263331 |
| CADPS | Ca++-dependent secretion activator | 0.0262581 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.025949 |
| STC2 | stanniocalcin 2 | 0.0255308 |
| MKRN1 | makorin ring finger protein 1 | 0.0250643 |
| COG5 | component of oligomeric golgi complex 5 | 0.0248655 |
| NRP1 | neuropilin 1 | 0.0245578 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.02453 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.024144 |
| UBN2 | ubinuclein 2 | 0.0238484 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0231701 |
| RBM6 | RNA binding motif protein 6 | 0.022587 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0224546 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0222558 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | 0.0219072 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0218683 |
| DIAPH1 | diaphanous-related formin 1 | 0.0212972 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0210414 |
| VEGFA | vascular endothelial growth factor A | 0.0208449 |
| BRD2 | bromodomain containing 2 | 0.0206991 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0206802 |
| CCNL1 | cyclin L1 | 0.0203449 |
| MTMR3 | myotubularin related protein 3 | 0.020338 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0202709 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0202631 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.020154 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0201375 |
| SIK3 | SIK family kinase 3 | 0.0200702 |
| PGK1 | phosphoglycerate kinase 1 | 0.0196447 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0196196 |
| INSIG1 | insulin induced gene 1 | 0.01932 |
| SEPTIN9 | septin 9 | 0.0190768 |
| GOLGB1 | golgin B1 | 0.019053 |
| SETX | senataxin | 0.0189056 |
| RYBP | RING1 and YY1 binding protein | 0.0189025 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0188904 |
| UBC | ubiquitin C | 0.0188614 |
| ADIPOR2 | adiponectin receptor 2 | 0.0188452 |
| SMAD2 | SMAD family member 2 | 0.0186779 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0185341 |
| TJP1 | tight junction protein 1 | 0.0184593 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0181376 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0179924 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0176914 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0176551 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0175628 |
| ZFP36 | ZFP36 ring finger protein | 0.0174864 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0174252 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0174051 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0173264 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0172805 |
| TAOK1 | TAO kinase 1 | 0.0169533 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0168959 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) | 0.0167147 |
| POTEF | POTE ankyrin domain family, member F | 0.0166501 |
| CLDN4 | claudin 4 | 0.0165443 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0165359 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0164628 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0164485 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0164312 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0161994 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.0161123 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0161031 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0160046 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.015995 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0159932 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0159832 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.0159723 |
| CDK13 | cyclin-dependent kinase 13 | 0.015913 |
| CPNE1 | copine I | 0.0158917 |
| COG6 | component of oligomeric golgi complex 6 | 0.0158382 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.232611 |
| TMSB10 | thymosin beta 10 | -0.159082 |
| KRT8 | keratin 8, type II | -0.114378 |
| FTL | ferritin, light polypeptide | -0.108245 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.102938 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0893599 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0873691 |
| RPL35A | ribosomal protein L35a | -0.0858229 |
| ACTN4 | actinin, alpha 4 | -0.0780924 |
| GNAS | GNAS complex locus | -0.076503 |
| RPS21 | ribosomal protein S21 | -0.0703189 |
| RPL23 | ribosomal protein L23 | -0.068605 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.063264 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0618795 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.06136 |
| SDC4 | syndecan 4 | -0.0589606 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0586007 |
| ANXA2 | annexin A2 | -0.0571808 |
| RPLP1 | ribosomal protein, large, P1 | -0.0552832 |
| IER3 | immediate early response 3 | -0.055257 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0541894 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0507664 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0500775 |
| RPL32 | ribosomal protein L32 | -0.0490477 |
| RPS27A | ribosomal protein S27a | -0.0486827 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0478006 |
| S100A10 | S100 calcium binding protein A10 | -0.0477097 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0473822 |
| RPL19 | ribosomal protein L19 | -0.0466707 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0446567 |
| RPL12 | ribosomal protein L12 | -0.0443558 |
| RPS19 | ribosomal protein S19 | -0.0440634 |
| H1-0 | H1.0 linker histone | -0.0435955 |
| LAMB3 | laminin, beta 3 | -0.0432632 |
| RPL37A | ribosomal protein L37a | -0.0429465 |
| RPLP2 | ribosomal protein, large, P2 | -0.0427469 |
| RNF43 | ring finger protein 43 | -0.041181 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0410371 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0409905 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0408107 |
| SERINC5 | serine incorporator 5 | -0.0399786 |
| PRELID2 | PRELI domain containing 2 | -0.0399465 |
| CCND1 | cyclin D1 | -0.039922 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0398408 |
| RPL18 | ribosomal protein L18 | -0.0397176 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0388439 |
| HMGB2 | high mobility group box 2 | -0.0388335 |
| ACTG1 | actin gamma 1 | -0.0382856 |
| FRMD5 | FERM domain containing 5 | -0.0381653 |
| RPL13A | ribosomal protein L13a | -0.0379856 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0371924 |
| RPL28 | ribosomal protein L28 | -0.0371781 |
| RPS3 | ribosomal protein S3 | -0.035438 |
| RPL8 | ribosomal protein L8 | -0.0353652 |
| KRT18 | keratin 18, type I | -0.0353602 |
| RPS6 | ribosomal protein S6 | -0.0352768 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0352102 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0347018 |
| TMSB4X | thymosin beta 4, X-linked | -0.0345319 |
| RPS24 | ribosomal protein S24 | -0.0344026 |
| RPL31 | ribosomal protein L31 | -0.0338327 |
| RPL37 | ribosomal protein L37 | -0.0336199 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0335548 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0333201 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0330842 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0326386 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.032104 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0318417 |
| RPL11 | ribosomal protein L11 | -0.0318412 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0318104 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0315687 |
| ARF1 | ADP-ribosylation factor 1 | -0.0305644 |
| RPL26 | ribosomal protein L26 | -0.0303044 |
| CDCP1 | CUB domain containing protein 1 | -0.0302905 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0301502 |
| RPL4 | ribosomal protein L4 | -0.0300025 |
| SQSTM1 | sequestosome 1 | -0.0297471 |
| EPCAM | epithelial cell adhesion molecule | -0.0297283 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0295582 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.0293813 |
| RPL34 | ribosomal protein L34 | -0.0292966 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0290272 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.0288816 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0288793 |
| RPS11 | ribosomal protein S11 | -0.0288717 |
| SEPTIN7 | septin 7 | -0.0285815 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0284912 |
| OLA1 | Obg-like ATPase 1 | -0.028412 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0283383 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0277104 |
| ZNF217 | zinc finger protein 217 | -0.0275424 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0274565 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0270612 |
| HMGB1 | high mobility group box 1 | -0.0270524 |
| HOXB3 | homeobox B3 | -0.02703 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0268344 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0267884 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.026749 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | -0.0264026 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0263318 |
