| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clobetasol propionate perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clobetasol propionate_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.17701 |
| FN1 | fibronectin 1 | 0.146116 |
| MT2A | metallothionein 2A | 0.143158 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0651283 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0517846 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0507774 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0466417 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0441978 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0425351 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0389161 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0371825 |
| FKBP5 | FK506 binding protein 5 | 0.0357494 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0310565 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0296886 |
| MT1X | metallothionein 1X | 0.0294343 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0293562 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0275276 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0268984 |
| PRELID2 | PRELI domain containing 2 | 0.026509 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0261926 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0259697 |
| MGST1 | microsomal glutathione S-transferase 1 | 0.0233715 |
| SRGN | serglycin | 0.023257 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0224836 |
| IRS2 | insulin receptor substrate 2 | 0.0223929 |
| FOXO3 | forkhead box O3 | 0.0217545 |
| DNER | delta/notch-like EGF repeat containing | 0.0216027 |
| TSC22D3 | TSC22 domain family, member 3 | 0.0215272 |
| JAK1 | Janus kinase 1 | 0.0212603 |
| VGLL3 | vestigial-like family member 3 | 0.0212132 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0209736 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0199076 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0195883 |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit | 0.0195594 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0186302 |
| INTS6 | integrator complex subunit 6 | 0.0173981 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0173965 |
| SH3RF3 | SH3 domain containing ring finger 3 | 0.01724 |
| FAM13A | family with sequence similarity 13, member A | 0.0168789 |
| PTX3 | pentraxin 3, long | 0.0166563 |
| PCNX1 | pecanex 1 | 0.0163031 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0162599 |
| TXNIP | thioredoxin interacting protein | 0.0159415 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0158565 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0150335 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0148217 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0147018 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0145158 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0144382 |
| TMEM87A | transmembrane protein 87A | 0.0144058 |
| LDHA | lactate dehydrogenase A | 0.0141007 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0139775 |
| SORT1 | sortilin 1 | 0.0139162 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0137881 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0130541 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0128308 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0122476 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.012173 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0121674 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0121596 |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 | 0.0120416 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0120197 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0120146 |
| MYOF | myoferlin | 0.0118667 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | 0.0117759 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0115727 |
| CLASP1 | cytoplasmic linker associated protein 1 | 0.0114647 |
| OGA | O-GlcNAcase | 0.0114631 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0114424 |
| PER1 | period circadian clock 1 | 0.0113853 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0111702 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0108988 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.010748 |
| CERS6 | ceramide synthase 6 | 0.0107177 |
| SUSD6 | sushi domain containing 6 | 0.0104183 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.010315 |
| MT1E | metallothionein 1E | 0.0102877 |
| CPM | carboxypeptidase M | 0.0100251 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.00997485 |
| KIAA1217 | KIAA1217 | 0.00994078 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0099122 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | 0.00985357 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.00983024 |
| ZFHX3 | zinc finger homeobox 3 | 0.00970792 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.00965858 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.00964678 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.00957337 |
| ZNF638 | zinc finger protein 638 | 0.00956801 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.00956176 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.00953757 |
| GLRX | glutaredoxin (thioltransferase) | 0.00944209 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.00925916 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.00920688 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.00908224 |
| RBM39 | RNA binding motif protein 39 | 0.00907503 |
| HMGB2 | high mobility group box 2 | 0.00904555 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.00891802 |
| IL6ST | interleukin 6 signal transducer | 0.00878746 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.00863567 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.00863478 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.348633 |
| INHBA | inhibin, beta A | -0.337192 |
| COL1A1 | collagen, type I, alpha 1 | -0.1996 |
| COL6A3 | collagen, type VI, alpha 3 | -0.185739 |
| COL1A2 | collagen, type I, alpha 2 | -0.136029 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.135227 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.115922 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.10984 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.103475 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.102839 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.097823 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0951732 |
| MMP1 | matrix metallopeptidase 1 | -0.0942182 |
| EMP1 | epithelial membrane protein 1 | -0.0858973 |
| NDRG1 | N-myc downstream regulated 1 | -0.084515 |
| STC1 | stanniocalcin 1 | -0.0844576 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0827162 |
| CD44 | CD44 molecule (Indian blood group) | -0.0826894 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0821849 |
| MYO10 | myosin X | -0.0802924 |
| ATP13A3 | ATPase type 13A3 | -0.0790263 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0757163 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0633502 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0607178 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0586564 |
| RAI14 | retinoic acid induced 14 | -0.05861 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0584389 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0573577 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0566542 |
| MAP1B | microtubule-associated protein 1B | -0.0557128 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.055505 |
| CAVIN1 | caveolae associated protein 1 | -0.0533937 |
| OXR1 | oxidation resistance 1 | -0.0530476 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0520527 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0515079 |
| NAV1 | neuron navigator 1 | -0.0505398 |
| ACTG1 | actin gamma 1 | -0.0504021 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0481726 |
| DST | dystonin | -0.0477555 |
| FBN1 | fibrillin 1 | -0.0473889 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0468019 |
| PRSS23 | protease, serine, 23 | -0.046226 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0459812 |
| LOXL2 | lysyl oxidase-like 2 | -0.0447171 |
| HLA-B | major histocompatibility complex, class I, B | -0.0446518 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0446234 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0445674 |
| FRMD4A | FERM domain containing 4A | -0.0419225 |
| CCND1 | cyclin D1 | -0.0412689 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0401975 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0393428 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0385535 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0382313 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0378648 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0376971 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0374494 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0372021 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0363105 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0362822 |
| TMSB10 | thymosin beta 10 | -0.0356265 |
| ASPH | aspartate beta-hydroxylase | -0.0354185 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0348521 |
| KIAA1549L | KIAA1549-like | -0.0346763 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0333097 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0331251 |
| CALU | calumenin | -0.0322051 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0317553 |
| POTEF | POTE ankyrin domain family, member F | -0.0313591 |
| S100A6 | S100 calcium binding protein A6 | -0.0308119 |
| GLIS3 | GLIS family zinc finger 3 | -0.0306914 |
| TMEM165 | transmembrane protein 165 | -0.0301659 |
| CALD1 | caldesmon 1 | -0.030142 |
| FTL | ferritin, light polypeptide | -0.0296887 |
| COL5A3 | collagen, type V, alpha 3 | -0.0295091 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0294412 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0293987 |
| CDH13 | cadherin 13 | -0.0293524 |
| PRRX1 | paired related homeobox 1 | -0.0291323 |
| CALR | calreticulin | -0.0290215 |
| HMGA2 | high mobility group AT-hook 2 | -0.0290008 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0289235 |
| PTMA | prothymosin, alpha | -0.0277687 |
| IER3 | immediate early response 3 | -0.0274024 |
| SEPTIN11 | septin 11 | -0.0270268 |
| TPM4 | tropomyosin 4 | -0.0268557 |
| B2M | beta-2-microglobulin | -0.0265583 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0264782 |
| VCAN | versican | -0.0263121 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0261231 |
| COL3A1 | collagen, type III, alpha 1 | -0.0258807 |
| ENO1 | enolase 1, (alpha) | -0.025727 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0247516 |
| RRBP1 | ribosome binding protein 1 | -0.024288 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.0239476 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0231877 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0231419 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0231352 |
| HLA-A | major histocompatibility complex, class I, A | -0.0231147 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0231022 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0229609 |
