| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clofarabine perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clofarabine_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.179816 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0838706 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0559777 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0512823 |
| FBN1 | fibrillin 1 | 0.0462032 |
| SEPTIN9 | septin 9 | 0.0457815 |
| PRELID2 | PRELI domain containing 2 | 0.0457302 |
| NAV2 | neuron navigator 2 | 0.0437573 |
| GPC6 | glypican 6 | 0.0435145 |
| FLNB | filamin B, beta | 0.043244 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0412994 |
| PTMA | prothymosin, alpha | 0.0390927 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0389053 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0385367 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0378512 |
| RPL37A | ribosomal protein L37a | 0.0367125 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0354938 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0351918 |
| SBF2 | SET binding factor 2 | 0.0348655 |
| RPS6 | ribosomal protein S6 | 0.0347609 |
| RPS3 | ribosomal protein S3 | 0.033194 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0331634 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0331116 |
| ATP13A3 | ATPase type 13A3 | 0.032614 |
| TAPBP | TAP binding protein (tapasin) | 0.0325791 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.031372 |
| FNIP1 | folliculin interacting protein 1 | 0.0301494 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0300149 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0282049 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0265913 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0261478 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.025837 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0257888 |
| ANO6 | anoctamin 6 | 0.0253986 |
| MSN | moesin | 0.0253437 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0250918 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0243786 |
| RPS12 | ribosomal protein S12 | 0.0240438 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0230011 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0226224 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0226093 |
| HDAC9 | histone deacetylase 9 | 0.0225615 |
| POTEF | POTE ankyrin domain family, member F | 0.022463 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0220109 |
| FAM219A | family with sequence similarity 219, member A | 0.021936 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0217036 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0210459 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0198503 |
| AUTS2 | autism susceptibility candidate 2 | 0.0198056 |
| ARRDC3 | arrestin domain containing 3 | 0.0196203 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0195841 |
| FRMD5 | FERM domain containing 5 | 0.0193241 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0190699 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0190237 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0189936 |
| FAM107B | family with sequence similarity 107, member B | 0.0189765 |
| ATXN1 | ataxin 1 | 0.0188421 |
| DTNA | dystrobrevin, alpha | 0.0186838 |
| FSD1L | fibronectin type III and SPRY domain containing 1-like | 0.0186652 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0184926 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0182503 |
| RNF145 | ring finger protein 145 | 0.0181992 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0180644 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0180566 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0178424 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0177807 |
| RPS8 | ribosomal protein S8 | 0.0175394 |
| AFDN | afadin, adherens junction formation factor | 0.0173742 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0173619 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0172774 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0172747 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0170309 |
| FOSL1 | FOS-like antigen 1 | 0.0169895 |
| SP3 | Sp3 transcription factor | 0.0167762 |
| RPS23 | ribosomal protein S23 | 0.0167153 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0164575 |
| TMF1 | TATA element modulatory factor 1 | 0.0162951 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0162528 |
| RAD51B | RAD51 paralog B | 0.0162293 |
| RPL31 | ribosomal protein L31 | 0.0162022 |
| STK10 | serine/threonine kinase 10 | 0.0161416 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0161085 |
| DST | dystonin | 0.0160728 |
| SQSTM1 | sequestosome 1 | 0.0160555 |
| MTSS1 | metastasis suppressor 1 | 0.0158786 |
| RPS19 | ribosomal protein S19 | 0.0158674 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0158429 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0158416 |
| NGLY1 | N-glycanase 1 | 0.0157665 |
| OGA | O-GlcNAcase | 0.0157501 |
| NAV1 | neuron navigator 1 | 0.0157139 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0156107 |
| FMNL2 | formin-like 2 | 0.0155663 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0155435 |
| YEATS2 | YEATS domain containing 2 | 0.0153972 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0153573 |
| RPS17 | ribosomal protein S17 | 0.0153374 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0151895 |
| SFTPA2 | surfactant protein A2 | 0.0150706 |
| MYOF | myoferlin | 0.0150425 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.323214 |
| VIM | vimentin | -0.31556 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.255767 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.196005 |
| LOX | lysyl oxidase | -0.184672 |
| TMSB10 | thymosin beta 10 | -0.153239 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.138797 |
| FN1 | fibronectin 1 | -0.101426 |
| S100A10 | S100 calcium binding protein A10 | -0.0925999 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0870778 |
| S100A6 | S100 calcium binding protein A6 | -0.0866628 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0853968 |
| CSTB | cystatin B (stefin B) | -0.085164 |
| ANXA2 | annexin A2 | -0.0742186 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0732914 |
| MAP1B | microtubule-associated protein 1B | -0.0702779 |
| CANX | calnexin | -0.069618 |
| THBS2 | thrombospondin 2 | -0.0678847 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0647922 |
| SLC38A1 | solute carrier family 38, member 1 | -0.063905 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0638508 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.060345 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0598562 |
| NDRG1 | N-myc downstream regulated 1 | -0.0574402 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0570172 |
| CALR | calreticulin | -0.0563085 |
| CDH13 | cadherin 13 | -0.0561285 |
| PODXL | podocalyxin-like | -0.0553479 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0552571 |
| HLA-B | major histocompatibility complex, class I, B | -0.054278 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0527797 |
| RIGI | RNA sensor RIG-I | -0.050972 |
| CAVIN1 | caveolae associated protein 1 | -0.0505537 |
| UBC | ubiquitin C | -0.0497387 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0486123 |
| LMNA | lamin A/C | -0.0483214 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0480468 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0478376 |
| AHNAK | AHNAK nucleoprotein | -0.0477912 |
| TAGLN2 | transgelin 2 | -0.0472411 |
| TPM4 | tropomyosin 4 | -0.0467612 |
| PRSS23 | protease, serine, 23 | -0.0465289 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0462384 |
| MYADM | myeloid-associated differentiation marker | -0.0440615 |
| S100A4 | S100 calcium binding protein A4 | -0.0415435 |
| COL5A1 | collagen, type V, alpha 1 | -0.0413528 |
| MT1X | metallothionein 1X | -0.0412443 |
| PKM | pyruvate kinase, muscle | -0.0401943 |
| BSG | basigin (Ok blood group) | -0.0397849 |
| RRBP1 | ribosome binding protein 1 | -0.0379498 |
| HLA-C | major histocompatibility complex, class I, C | -0.0375975 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0375915 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0375357 |
| COPA | coatomer protein complex, subunit alpha | -0.0364751 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0364405 |
| LDHA | lactate dehydrogenase A | -0.0363024 |
| IL7R | interleukin 7 receptor | -0.0355379 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0351534 |
| COL5A2 | collagen, type V, alpha 2 | -0.0350504 |
| AFF4 | AF4/FMR2 family, member 4 | -0.03492 |
| RAI1 | retinoic acid induced 1 | -0.0346945 |
| LRRC17 | leucine rich repeat containing 17 | -0.034505 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0343191 |
| LOC112694756 | uncharaterized LOC112694756 | -0.034256 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0340393 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0337614 |
| ZNF207 | zinc finger protein 207 | -0.0332669 |
| DCLK2 | doublecortin-like kinase 2 | -0.0320921 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0315744 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0314912 |
| B2M | beta-2-microglobulin | -0.0311799 |
| SP100 | SP100 nuclear antigen | -0.0305468 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0301284 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0294744 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0293654 |
| GNAS | GNAS complex locus | -0.0292238 |
| MX2 | MX dynamin-like GTPase 2 | -0.0291834 |
| ARF1 | ADP-ribosylation factor 1 | -0.028541 |
| TMSB4X | thymosin beta 4, X-linked | -0.0284878 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0283821 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0275653 |
| FBXO11 | F-box protein 11 | -0.0272923 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0272024 |
| SEPTIN7 | septin 7 | -0.0271128 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0269308 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0268449 |
| PLXNA2 | plexin A2 | -0.0265591 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0264048 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0261349 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0258802 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0254856 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0251205 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0248308 |
| SUCNR1 | succinate receptor 1 | -0.024455 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0243165 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0241337 |
| EGFR | epidermal growth factor receptor | -0.0240952 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.0239035 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0231174 |
| CCND1 | cyclin D1 | -0.0230186 |
