| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clofarabine perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clofarabine_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0794043 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0662714 |
| YBX3 | Y box binding protein 3 | 0.0638011 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0590285 |
| TMEM41B | transmembrane protein 41B | 0.0522896 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0519922 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0514499 |
| KIF5B | kinesin family member 5B | 0.0415828 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0401044 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0389501 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0379499 |
| CCNL1 | cyclin L1 | 0.0370418 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0361688 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0351015 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0347996 |
| ECT2 | epithelial cell transforming 2 | 0.0343547 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0339673 |
| NEK7 | NIMA-related kinase 7 | 0.0334536 |
| XPO1 | exportin 1 | 0.0330203 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0327333 |
| H1-0 | H1.0 linker histone | 0.0327177 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0326286 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0322985 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0321756 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0318694 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0312089 |
| TNPO1 | transportin 1 | 0.0311821 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0299925 |
| AREG | amphiregulin | 0.0296325 |
| MATR3 | matrin 3 | 0.0291126 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0290623 |
| GASK1B | golgi associated kinase 1B | 0.0289311 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0281377 |
| THOC1 | THO complex 1 | 0.0278449 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0271184 |
| LMO7 | LIM domain 7 | 0.0269556 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0268619 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0266931 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0265579 |
| OGA | O-GlcNAcase | 0.0265462 |
| KLF6 | Kruppel-like factor 6 | 0.0261008 |
| NKTR | natural killer cell triggering receptor | 0.0260812 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0256412 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0254897 |
| KLHL24 | kelch-like family member 24 | 0.0250743 |
| MED13L | mediator complex subunit 13-like | 0.0244419 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0243704 |
| HMGB2 | high mobility group box 2 | 0.0243211 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0242628 |
| WDR43 | WD repeat domain 43 | 0.0240049 |
| TXNRD1 | thioredoxin reductase 1 | 0.0235153 |
| AXIN2 | axin 2 | 0.0234735 |
| TPR | translocated promoter region, nuclear basket protein | 0.0229612 |
| CEP192 | centrosomal protein 192kDa | 0.0228987 |
| CENPF | centromere protein F, 350/400kDa | 0.0228191 |
| CEP95 | centrosomal protein 95kDa | 0.0227029 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0226129 |
| ZNF292 | zinc finger protein 292 | 0.0225412 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0224483 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0222233 |
| SERINC1 | serine incorporator 1 | 0.0221931 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0216613 |
| NCKAP1 | NCK-associated protein 1 | 0.0216561 |
| OXR1 | oxidation resistance 1 | 0.0215326 |
| PNN | pinin, desmosome associated protein | 0.0210872 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0210662 |
| ZNF217 | zinc finger protein 217 | 0.0208375 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0205514 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0202271 |
| AFG3L2 | AFG3-like AAA ATPase 2 | 0.0201588 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0201289 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0199484 |
| ARRDC3 | arrestin domain containing 3 | 0.0199095 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0198835 |
| CDK17 | cyclin-dependent kinase 17 | 0.0196486 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0195495 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0193675 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.019332 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0192984 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0192636 |
| CPOX | coproporphyrinogen oxidase | 0.0190636 |
| RBM39 | RNA binding motif protein 39 | 0.0189374 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0188749 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0188085 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0187177 |
| QKI | QKI, KH domain containing, RNA binding | 0.0185968 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.018366 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0183411 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0182488 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0182025 |
| CDK19 | cyclin-dependent kinase 19 | 0.018063 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0179461 |
| RBM25 | RNA binding motif protein 25 | 0.0179173 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0179006 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0178556 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | 0.0177485 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0175364 |
| SPAG9 | sperm associated antigen 9 | 0.0174906 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0174605 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0173773 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.339197 |
| VIM | vimentin | -0.260409 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.226535 |
| HMGA2 | high mobility group AT-hook 2 | -0.175692 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.131475 |
| NLGN1 | neuroligin 1 | -0.118124 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.094348 |
| EHBP1 | EH domain binding protein 1 | -0.0866711 |
| ACTG1 | actin gamma 1 | -0.0805744 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0785386 |
| PCDH7 | protocadherin 7 | -0.0777734 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0777225 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0731479 |
| EGR1 | early growth response 1 | -0.0683755 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0648997 |
| TMSB10 | thymosin beta 10 | -0.0642708 |
| MMP12 | matrix metallopeptidase 12 | -0.0637807 |
| HMGA1 | high mobility group AT-hook 1 | -0.0589902 |
| INTS6 | integrator complex subunit 6 | -0.0573119 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0557691 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0532919 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0532388 |
| FTL | ferritin, light polypeptide | -0.0529699 |
| NHSL1 | NHS-like 1 | -0.0519597 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0516194 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.051172 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0507497 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0502404 |
| TUBA1B | tubulin, alpha 1b | -0.0493931 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0489376 |
| ADIPOR2 | adiponectin receptor 2 | -0.0480329 |
| RASAL2 | RAS protein activator like 2 | -0.0465254 |
| YAP1 | Yes-associated protein 1 | -0.0459081 |
| BPTF | bromodomain PHD finger transcription factor | -0.0442089 |
| ASPH | aspartate beta-hydroxylase | -0.0434967 |
| CCN2 | cellular communication network factor 2 | -0.0418479 |
| POTEF | POTE ankyrin domain family, member F | -0.040514 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0396071 |
| ZNF804A | zinc finger protein 804A | -0.0395106 |
| BCHE | butyrylcholinesterase | -0.0389036 |
| RPS23 | ribosomal protein S23 | -0.0382808 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0381031 |
| RPS8 | ribosomal protein S8 | -0.0379784 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0377872 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0367252 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0362827 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0360669 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.035967 |
| RPS13 | ribosomal protein S13 | -0.035923 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0352848 |
| LRRC23 | leucine rich repeat containing 23 | -0.0346994 |
| CUX1 | cut-like homeobox 1 | -0.0344919 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0336498 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0335222 |
| TBCA | tubulin folding cofactor A | -0.0334081 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0328984 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.032619 |
| CANX | calnexin | -0.0322914 |
| CMIP | c-Maf inducing protein | -0.0322685 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | -0.0320982 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0316376 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0316018 |
| RPS29 | ribosomal protein S29 | -0.0314697 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0312929 |
| TPM4 | tropomyosin 4 | -0.0310848 |
| CCND1 | cyclin D1 | -0.0305473 |
| EGFR | epidermal growth factor receptor | -0.029786 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0294117 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0289887 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0288482 |
| HLA-A | major histocompatibility complex, class I, A | -0.0283803 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | -0.0281851 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0279875 |
| ZNF638 | zinc finger protein 638 | -0.0276788 |
| RPL37A | ribosomal protein L37a | -0.0276299 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0276116 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.027448 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0273413 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0272057 |
| CALR | calreticulin | -0.0266542 |
| MAP1B | microtubule-associated protein 1B | -0.0265731 |
| R3HDM2 | R3H domain containing 2 | -0.026466 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0264638 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0263802 |
| S100A10 | S100 calcium binding protein A10 | -0.0262672 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0260025 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.025695 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0254694 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0254139 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0253847 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0251764 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0251298 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0250896 |
| NEBL | nebulette | -0.0250425 |
| RHOA | ras homolog family member A | -0.0247093 |
| LDHB | lactate dehydrogenase B | -0.0244746 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.024437 |
| RPL31 | ribosomal protein L31 | -0.0242093 |
| KSR2 | kinase suppressor of ras 2 | -0.0241761 |
| DTNA | dystrobrevin, alpha | -0.0240156 |
