| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clofarabine perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clofarabine_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LPIN1 | lipin 1 | 0.121999 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0915138 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.088741 |
| FAM13A | family with sequence similarity 13, member A | 0.0751989 |
| PTMA | prothymosin, alpha | 0.0731366 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0594893 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0552549 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0529692 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.05296 |
| MEIS2 | Meis homeobox 2 | 0.05125 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0510769 |
| RPS6 | ribosomal protein S6 | 0.0504912 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0479918 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0477468 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0427672 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0422012 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0411029 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0394509 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0387786 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0384686 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0381769 |
| COL3A1 | collagen, type III, alpha 1 | 0.0377489 |
| DST | dystonin | 0.0376947 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0366954 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0345573 |
| RPS2 | ribosomal protein S2 | 0.0339765 |
| AHNAK | AHNAK nucleoprotein | 0.0336061 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0331066 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0328285 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0325882 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0325686 |
| TLE4 | transducin-like enhancer of split 4 | 0.0322895 |
| SET | SET nuclear proto-oncogene | 0.0320283 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0318848 |
| AOPEP | aminopeptidase O (putative) | 0.0315618 |
| HMGB2 | high mobility group box 2 | 0.0314669 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0312291 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0302922 |
| APP | amyloid beta (A4) precursor protein | 0.0287768 |
| RNF213 | ring finger protein 213 | 0.0286902 |
| NCKAP1 | NCK-associated protein 1 | 0.0286502 |
| KLHL13 | kelch-like family member 13 | 0.0283788 |
| SMARCE1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 | 0.0280077 |
| RBM25 | RNA binding motif protein 25 | 0.0279701 |
| WDR43 | WD repeat domain 43 | 0.0275527 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0275369 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0274654 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0272704 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0270403 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0270007 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0268339 |
| KIF5B | kinesin family member 5B | 0.0262048 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0260798 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0259709 |
| RPL14 | ribosomal protein L14 | 0.0257471 |
| RPS3 | ribosomal protein S3 | 0.0257402 |
| RPL26 | ribosomal protein L26 | 0.025666 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0256147 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0250309 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0248795 |
| SEPTIN9 | septin 9 | 0.0241988 |
| FOXO3 | forkhead box O3 | 0.0236866 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0235188 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0234206 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0233105 |
| YME1L1 | YME1-like 1 ATPase | 0.0232088 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0232032 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0231101 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0230362 |
| HAS2 | hyaluronan synthase 2 | 0.0228958 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0226009 |
| SERINC1 | serine incorporator 1 | 0.0225532 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0224241 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0222837 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0221955 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0221855 |
| SBF2 | SET binding factor 2 | 0.022159 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0220629 |
| TBX2 | T-box 2 | 0.0219416 |
| ASPH | aspartate beta-hydroxylase | 0.0218798 |
| PNN | pinin, desmosome associated protein | 0.0218646 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0214504 |
| PARD3 | par-3 family cell polarity regulator | 0.021364 |
| SMAD3 | SMAD family member 3 | 0.0213215 |
| PHF3 | PHD finger protein 3 | 0.0213114 |
| RBM39 | RNA binding motif protein 39 | 0.0212688 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.021161 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0211428 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0210134 |
| ARRDC3 | arrestin domain containing 3 | 0.0209105 |
| CENPF | centromere protein F, 350/400kDa | 0.0208655 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0208439 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0207814 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0207735 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0207203 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0205932 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0203253 |
| CLTC | clathrin, heavy chain (Hc) | 0.0202885 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0202146 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0201618 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.39416 |
| NRG1 | neuregulin 1 | -0.141939 |
| VIM | vimentin | -0.0659745 |
| VCL | vinculin | -0.0632759 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0616822 |
| GDF15 | growth differentiation factor 15 | -0.059025 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0572033 |
| BPTF | bromodomain PHD finger transcription factor | -0.054896 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0546883 |
| NDRG1 | N-myc downstream regulated 1 | -0.0538894 |
| SYT1 | synaptotagmin I | -0.0538403 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0532909 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0522236 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0429086 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0428823 |
| MCL1 | myeloid cell leukemia 1 | -0.0392643 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0378318 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.037731 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0364799 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0361036 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0355642 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0352076 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.033701 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0335272 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0333813 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0331233 |
| EXT1 | exostosin glycosyltransferase 1 | -0.032504 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0320562 |
| STC1 | stanniocalcin 1 | -0.0309298 |
| GPC5 | glypican 5 | -0.0306296 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0293948 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0292584 |
| EGR1 | early growth response 1 | -0.0284153 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.028017 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0280102 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.027769 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0276136 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0275247 |
| COPA | coatomer protein complex, subunit alpha | -0.0273526 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0265956 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0264263 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0262271 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0259135 |
| ATRNL1 | attractin-like 1 | -0.0257115 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0254639 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0253623 |
| CTBP2 | C-terminal binding protein 2 | -0.0253605 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.025147 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0250604 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0244461 |
| ACTG1 | actin gamma 1 | -0.0240601 |
| ZNF609 | zinc finger protein 609 | -0.0240284 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0235512 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0234661 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0232321 |
| PLAT | plasminogen activator, tissue | -0.0230166 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0228715 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0228696 |
| AEBP2 | AE binding protein 2 | -0.0227957 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0225707 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0222529 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0221952 |
| HM13 | histocompatibility (minor) 13 | -0.0219348 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0217021 |
| INTS6 | integrator complex subunit 6 | -0.0216793 |
| TMSB10 | thymosin beta 10 | -0.0216592 |
| EXOC4 | exocyst complex component 4 | -0.021638 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0214984 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0214754 |
| NBEA | neurobeachin | -0.0210393 |
| HMGA1 | high mobility group AT-hook 1 | -0.0209545 |
| ADAMTS19 | ADAM metallopeptidase with thrombospondin type 1 motif, 19 | -0.0207472 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0206812 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0205664 |
| ZNF804A | zinc finger protein 804A | -0.0204994 |
| AHR | aryl hydrocarbon receptor | -0.0204322 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.020304 |
| CADM2 | cell adhesion molecule 2 | -0.0200899 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0200829 |
| SCFD1 | sec1 family domain containing 1 | -0.0200279 |
| LIMA1 | LIM domain and actin binding 1 | -0.0197657 |
| HMGA2 | high mobility group AT-hook 2 | -0.01973 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0197233 |
| GOLPH3L | golgi phosphoprotein 3-like | -0.0195982 |
| MYO1E | myosin IE | -0.0194844 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0194628 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0194015 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0193734 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0190129 |
| FRMD4A | FERM domain containing 4A | -0.0189957 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0188923 |
| KCNIP4 | Kv channel interacting protein 4 | -0.0188679 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0185578 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0185049 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0184756 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0184122 |
| FTL | ferritin, light polypeptide | -0.0183969 |
| DIAPH2 | diaphanous-related formin 2 | -0.0183714 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | -0.018353 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0182934 |