| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clofarabine perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clofarabine_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BTBD9 | BTB (POZ) domain containing 9 | 0.0587988 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0547934 |
| PRELID2 | PRELI domain containing 2 | 0.0497227 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.045755 |
| IFNGR1 | interferon gamma receptor 1 | 0.0455907 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0454353 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0448125 |
| RNF43 | ring finger protein 43 | 0.0446678 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0416983 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.041541 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0403473 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0392537 |
| PHF3 | PHD finger protein 3 | 0.0383559 |
| RPS6 | ribosomal protein S6 | 0.038012 |
| GOLGA4 | golgin A4 | 0.0367835 |
| RBM26 | RNA binding motif protein 26 | 0.0367763 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0355797 |
| RAD51B | RAD51 paralog B | 0.0341039 |
| ASPH | aspartate beta-hydroxylase | 0.0340461 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0339195 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0335488 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.032203 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0312343 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0311366 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0300571 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.029839 |
| ARRDC3 | arrestin domain containing 3 | 0.0293093 |
| RPS3 | ribosomal protein S3 | 0.0293004 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0292346 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0289951 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0285755 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0271078 |
| EHF | ets homologous factor | 0.0266741 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0264202 |
| DIAPH3 | diaphanous-related formin 3 | 0.0264196 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.026165 |
| ARGLU1 | arginine and glutamate rich 1 | 0.02588 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.025863 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0249645 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0246108 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.024546 |
| RBM39 | RNA binding motif protein 39 | 0.024506 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0243769 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0243088 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0239088 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0236517 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0235229 |
| UBAC2 | UBA domain containing 2 | 0.0234111 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0233471 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0229613 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0229451 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0228411 |
| TUBGCP3 | tubulin, gamma complex associated protein 3 | 0.0228293 |
| FNIP1 | folliculin interacting protein 1 | 0.0228284 |
| MEF2A | myocyte enhancer factor 2A | 0.0228195 |
| SUCO | SUN domain containing ossification factor | 0.0228135 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0227599 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0225426 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0224787 |
| KIF16B | kinesin family member 16B | 0.0224056 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0223305 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0222754 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.022255 |
| SBF2 | SET binding factor 2 | 0.0222025 |
| GOLGB1 | golgin B1 | 0.0220721 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0220191 |
| FAT1 | FAT atypical cadherin 1 | 0.0216742 |
| LDHA | lactate dehydrogenase A | 0.0213295 |
| DSPP | dentin sialophosphoprotein | 0.021287 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0211891 |
| STK24 | serine/threonine kinase 24 | 0.0210906 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0209729 |
| FNDC3A | fibronectin type III domain containing 3A | 0.020961 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.020935 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | 0.020834 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0207285 |
| RNF145 | ring finger protein 145 | 0.0202808 |
| PTEN | phosphatase and tensin homolog | 0.0202316 |
| YEATS2 | YEATS domain containing 2 | 0.020177 |
| OGA | O-GlcNAcase | 0.0201187 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.020067 |
| MLPH | melanophilin | 0.0200281 |
| ZNF148 | zinc finger protein 148 | 0.0200162 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0199143 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0198248 |
| CUL3 | cullin 3 | 0.0196475 |
| LRRC1 | leucine rich repeat containing 1 | 0.0196023 |
| PDS5B | PDS5 cohesin associated factor B | 0.0195872 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0195338 |
| ANO6 | anoctamin 6 | 0.0195261 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0194748 |
| WDR26 | WD repeat domain 26 | 0.0193459 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0193296 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0192617 |
| WDR33 | WD repeat domain 33 | 0.0192196 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0191645 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0189065 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0188337 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0186508 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.018626 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.206404 |
| EGR1 | early growth response 1 | -0.188858 |
| ANXA2 | annexin A2 | -0.1396 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.129256 |
| B2M | beta-2-microglobulin | -0.12262 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.113139 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.110147 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.10809 |
| EZR | ezrin | -0.10088 |
| PERP | PERP, TP53 apoptosis effector | -0.0997201 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0988394 |
| MYO1E | myosin IE | -0.0968081 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0961614 |
| RNF213 | ring finger protein 213 | -0.0957032 |
| INTS6 | integrator complex subunit 6 | -0.0897613 |
| SQSTM1 | sequestosome 1 | -0.0830727 |
| LCN2 | lipocalin 2 | -0.0830542 |
| HLA-B | major histocompatibility complex, class I, B | -0.0826373 |
| RIGI | RNA sensor RIG-I | -0.0805914 |
| PKM | pyruvate kinase, muscle | -0.0787466 |
| LYZ | lysozyme | -0.0780512 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0745399 |
| MX1 | MX dynamin-like GTPase 1 | -0.0743499 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0732287 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0728104 |
| JUN | jun proto-oncogene | -0.0701402 |
| MX2 | MX dynamin-like GTPase 2 | -0.0694734 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0689721 |
| TMC5 | transmembrane channel-like 5 | -0.0682794 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0655397 |
| PLSCR1 | phospholipid scramblase 1 | -0.0651658 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0649679 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0647627 |
| MACC1 | metastasis associated in colon cancer 1 | -0.062664 |
| IRF1 | interferon regulatory factor 1 | -0.0611084 |
| AREG | amphiregulin | -0.0606361 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0603637 |
| SP100 | SP100 nuclear antigen | -0.0575272 |
| TJP1 | tight junction protein 1 | -0.0568762 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.054103 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0540796 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0526854 |
| HLA-E | major histocompatibility complex, class I, E | -0.0514198 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0493646 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0485202 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0478749 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0476274 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0459866 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0455737 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0455354 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0451427 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0441249 |
| EPHB2 | EPH receptor B2 | -0.0437663 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0426606 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0420135 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0418466 |
| ITGA6 | integrin, alpha 6 | -0.0410908 |
| RBM47 | RNA binding motif protein 47 | -0.0409875 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0404497 |
| MCL1 | myeloid cell leukemia 1 | -0.0404317 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0397015 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0394918 |
| ACTG1 | actin gamma 1 | -0.0386515 |
| MORF4L2 | mortality factor 4 like 2 | -0.0386229 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0375424 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0374776 |
| S100A6 | S100 calcium binding protein A6 | -0.0373167 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0371658 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0368514 |
| FTL | ferritin, light polypeptide | -0.0366814 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0366445 |
| EFNB2 | ephrin-B2 | -0.0363646 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0359739 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -0.0359541 |
| UBC | ubiquitin C | -0.0359071 |
| MUC20 | mucin 20, cell surface associated | -0.0358119 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0354792 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0352826 |
| HLA-A | major histocompatibility complex, class I, A | -0.0352438 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0352313 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0350264 |
| HM13 | histocompatibility (minor) 13 | -0.0348974 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0346942 |
| IRS2 | insulin receptor substrate 2 | -0.034406 |
| UBAP2 | ubiquitin associated protein 2 | -0.0343073 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0342492 |
| MAP7 | microtubule-associated protein 7 | -0.0339738 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0337437 |
| HLA-C | major histocompatibility complex, class I, C | -0.0337072 |
| TRIM2 | tripartite motif containing 2 | -0.0336818 |
| DUSP10 | dual specificity phosphatase 10 | -0.0335225 |
| PMP22 | peripheral myelin protein 22 | -0.0331125 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0327025 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0326154 |
| MUC13 | mucin 13, cell surface associated | -0.0323963 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0321686 |
| S100A10 | S100 calcium binding protein A10 | -0.0318265 |
| CCNL1 | cyclin L1 | -0.0317683 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0317562 |
| ERBIN | erbb2 interacting protein | -0.0313123 |