| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clofarabine perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clofarabine_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.154264 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.151485 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.121006 |
| MT2A | metallothionein 2A | 0.114552 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.110609 |
| RPS6 | ribosomal protein S6 | 0.0891753 |
| RPS3 | ribosomal protein S3 | 0.0839055 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0834832 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0834773 |
| VEGFA | vascular endothelial growth factor A | 0.0782187 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0765418 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0758566 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0755981 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0697824 |
| NDRG1 | N-myc downstream regulated 1 | 0.0689883 |
| GOLGA4 | golgin A4 | 0.0681218 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0679313 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0676929 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.066419 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0628885 |
| RPS8 | ribosomal protein S8 | 0.0622193 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0590296 |
| PDE10A | phosphodiesterase 10A | 0.0572231 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0555701 |
| MTSS1 | metastasis suppressor 1 | 0.0554762 |
| PTMA | prothymosin, alpha | 0.0547601 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0532278 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0523272 |
| COL5A1 | collagen, type V, alpha 1 | 0.0516194 |
| TAPBP | TAP binding protein (tapasin) | 0.0511703 |
| CALR | calreticulin | 0.0497533 |
| RPS12 | ribosomal protein S12 | 0.0497329 |
| LOXL2 | lysyl oxidase-like 2 | 0.0491845 |
| RPL37A | ribosomal protein L37a | 0.0481221 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0475157 |
| RPS2 | ribosomal protein S2 | 0.0474717 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0467214 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0456895 |
| RPS19 | ribosomal protein S19 | 0.0452606 |
| RPL36 | ribosomal protein L36 | 0.0450689 |
| ANKRD11 | ankyrin repeat domain 11 | 0.04481 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0441529 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0415973 |
| NAV2 | neuron navigator 2 | 0.0414255 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.041335 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0412228 |
| ARRDC3 | arrestin domain containing 3 | 0.0411113 |
| FMNL2 | formin-like 2 | 0.0410731 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0408617 |
| LDHA | lactate dehydrogenase A | 0.0406704 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0398657 |
| ATP13A3 | ATPase type 13A3 | 0.0375995 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0375805 |
| RACK1 | receptor for activated C kinase 1 | 0.0366638 |
| VCAN | versican | 0.0365429 |
| CTSB | cathepsin B | 0.0360629 |
| TMF1 | TATA element modulatory factor 1 | 0.0355947 |
| EFNA5 | ephrin-A5 | 0.0354918 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0351619 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0343398 |
| RUNX1 | runt-related transcription factor 1 | 0.034243 |
| B2M | beta-2-microglobulin | 0.0341376 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0338235 |
| MSN | moesin | 0.0338116 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0332587 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0322302 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0315846 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.031437 |
| RPL37 | ribosomal protein L37 | 0.0314227 |
| SQLE | squalene epoxidase | 0.0313792 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.031323 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0311958 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0310064 |
| RPL7 | ribosomal protein L7 | 0.0307573 |
| ZNF292 | zinc finger protein 292 | 0.030592 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0303546 |
| GOLGB1 | golgin B1 | 0.0300617 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0300039 |
| PRELID2 | PRELI domain containing 2 | 0.0298487 |
| BRD2 | bromodomain containing 2 | 0.0295247 |
| RPL26 | ribosomal protein L26 | 0.0293929 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0289005 |
| SMAD3 | SMAD family member 3 | 0.028651 |
| CADM1 | cell adhesion molecule 1 | 0.0282006 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0280575 |
| RPS21 | ribosomal protein S21 | 0.0276295 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0271491 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0267831 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.026366 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.025985 |
| H1-4 | H1.4 linker histone, cluster member | 0.0256221 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0255761 |
| RPL11 | ribosomal protein L11 | 0.0255628 |
| FLNB | filamin B, beta | 0.0255062 |
| RPL18 | ribosomal protein L18 | 0.0253499 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0249336 |
| TMSB4X | thymosin beta 4, X-linked | 0.0247382 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0244712 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0243523 |
| RPL35A | ribosomal protein L35a | 0.0242801 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.30635 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.186793 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.182498 |
| VIM | vimentin | -0.116748 |
| COL1A1 | collagen, type I, alpha 1 | -0.0837159 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0677875 |
| IER3 | immediate early response 3 | -0.0645225 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0629558 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0542004 |
| COL1A2 | collagen, type I, alpha 2 | -0.0442648 |
| LOX | lysyl oxidase | -0.0425668 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.042373 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0375745 |
| OSMR | oncostatin M receptor | -0.0373452 |
| PALLD | palladin, cytoskeletal associated protein | -0.0369141 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0347536 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0341277 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0330891 |
| EXT1 | exostosin glycosyltransferase 1 | -0.030985 |
| HMGA2 | high mobility group AT-hook 2 | -0.0304933 |
| RPS24 | ribosomal protein S24 | -0.0303069 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0289577 |
| GLIS3 | GLIS family zinc finger 3 | -0.0281524 |
| FBN1 | fibrillin 1 | -0.027894 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0275836 |
| PXDN | peroxidasin | -0.0274531 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0272244 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0265042 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0254478 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0252867 |
| S100A10 | S100 calcium binding protein A10 | -0.0249142 |
| EGR1 | early growth response 1 | -0.0244248 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0238906 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0238157 |
| BSG | basigin (Ok blood group) | -0.0236477 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0235276 |
| TMEM123 | transmembrane protein 123 | -0.0231176 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0228575 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0223416 |
| CD44 | CD44 molecule (Indian blood group) | -0.021879 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0215947 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0215672 |
| HLA-B | major histocompatibility complex, class I, B | -0.0213403 |
| CNTN5 | contactin 5 | -0.0210462 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0210157 |
| VCL | vinculin | -0.0205578 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0205021 |
| PITPNB | phosphatidylinositol transfer protein, beta | -0.0203301 |
| NABP1 | nucleic acid binding protein 1 | -0.0202204 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0193373 |
| EHD2 | EH-domain containing 2 | -0.0192845 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0191316 |
| CCND1 | cyclin D1 | -0.018725 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0186481 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0182874 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0181469 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0179646 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.0178144 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0178015 |
| TUBB | tubulin, beta class I | -0.0177882 |
| ZNF207 | zinc finger protein 207 | -0.0177817 |
| XPO7 | exportin 7 | -0.0176717 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0174301 |
| CDH13 | cadherin 13 | -0.0173 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0172035 |
| TUBA1B | tubulin, alpha 1b | -0.0171693 |
| TKT | transketolase | -0.0170134 |
| CTSD | cathepsin D | -0.0164072 |
| POSTN | periostin, osteoblast specific factor | -0.0160413 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0159651 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0159062 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.015856 |
| HMCN1 | hemicentin 1 | -0.0157857 |
| HMGB1 | high mobility group box 1 | -0.0156737 |
| AFF4 | AF4/FMR2 family, member 4 | -0.015606 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0155451 |
| GNS | glucosamine (N-acetyl)-6-sulfatase | -0.0155447 |
| ITGA11 | integrin, alpha 11 | -0.0153589 |
| ERBIN | erbb2 interacting protein | -0.0152819 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.01522 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0151532 |
| NEK10 | NIMA-related kinase 10 | -0.0150429 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0149149 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0146941 |
| NREP | neuronal regeneration related protein | -0.0146467 |
| MT1X | metallothionein 1X | -0.0146412 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | -0.0145213 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0145072 |
| MTPN | myotrophin | -0.0142446 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0140761 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.0140175 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0139209 |
| RHEB | Ras homolog enriched in brain | -0.0138857 |
| AFTPH | aftiphilin | -0.0136231 |
| HMGA1 | high mobility group AT-hook 1 | -0.0135366 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 | -0.013505 |
| CALU | calumenin | -0.013372 |
| WASF2 | WAS protein family, member 2 | -0.0133102 |
| SMIM14 | small integral membrane protein 14 | -0.0132703 |
| HBP1 | HMG-box transcription factor 1 | -0.0132451 |
