| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clofarabine perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clofarabine_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.198982 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.15776 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0971105 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0675777 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0602984 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0577204 |
| KIAA1217 | KIAA1217 | 0.0547736 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0508831 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0486633 |
| DTNA | dystrobrevin, alpha | 0.0481299 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0479672 |
| INSIG2 | insulin induced gene 2 | 0.0476035 |
| ASPH | aspartate beta-hydroxylase | 0.0444637 |
| FNIP1 | folliculin interacting protein 1 | 0.0426091 |
| RTN4 | reticulon 4 | 0.0420603 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0393584 |
| TNS1 | tensin 1 | 0.0381402 |
| ENO1 | enolase 1, (alpha) | 0.0379918 |
| NDRG1 | N-myc downstream regulated 1 | 0.0354646 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0339709 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0335135 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0330764 |
| PLIN2 | perilipin 2 | 0.0327742 |
| NCKAP1 | NCK-associated protein 1 | 0.0325582 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0322808 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0314173 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0309854 |
| MYO1B | myosin IB | 0.0305356 |
| NGLY1 | N-glycanase 1 | 0.0299094 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0294621 |
| PTK2 | protein tyrosine kinase 2 | 0.028909 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0284575 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0284152 |
| VEGFA | vascular endothelial growth factor A | 0.0283815 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0280962 |
| ALPK2 | alpha-kinase 2 | 0.0276482 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0275848 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0274964 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0274388 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0269794 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0268012 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.025822 |
| NPTN | neuroplastin | 0.0258167 |
| YEATS2 | YEATS domain containing 2 | 0.0257537 |
| AFDN | afadin, adherens junction formation factor | 0.0255243 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0254491 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.025204 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0248718 |
| ZNF292 | zinc finger protein 292 | 0.0247926 |
| SBF2 | SET binding factor 2 | 0.0246631 |
| DSPP | dentin sialophosphoprotein | 0.0242797 |
| POTEF | POTE ankyrin domain family, member F | 0.0242337 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0241472 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0240217 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0232821 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.02313 |
| HELZ | helicase with zinc finger | 0.0230116 |
| SVIL | supervillin | 0.0227521 |
| A1CF | APOBEC1 complementation factor | 0.0225332 |
| ANO6 | anoctamin 6 | 0.0223771 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0222984 |
| KIF21A | kinesin family member 21A | 0.0219031 |
| USP47 | ubiquitin specific peptidase 47 | 0.0212402 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0212029 |
| FERMT2 | fermitin family member 2 | 0.0210349 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0208628 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0208511 |
| CRLS1 | cardiolipin synthase 1 | 0.0207862 |
| SLK | STE20-like kinase | 0.0203347 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0203092 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.020269 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.0201474 |
| ABCD3 | ATP-binding cassette, sub-family D (ALD), member 3 | 0.0200148 |
| VIM | vimentin | 0.0200046 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0198101 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0197118 |
| TASOR2 | transcription activation suppressor family member 2 | 0.0195911 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0195158 |
| SETD5 | SET domain containing 5 | 0.0193236 |
| TMEM263 | transmembrane protein 263 | 0.0191082 |
| RNF149 | ring finger protein 149 | 0.0190437 |
| HLF | hepatic leukemia factor | 0.018953 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.018789 |
| ZNF148 | zinc finger protein 148 | 0.0187705 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.018754 |
| YAP1 | Yes-associated protein 1 | 0.0186379 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0185373 |
| KYNU | kynureninase | 0.0184881 |
| AXIN2 | axin 2 | 0.0184093 |
| RLF | rearranged L-myc fusion | 0.0183991 |
| CORO1C | coronin, actin binding protein, 1C | 0.0183792 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0181134 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.017993 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 0.0179628 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0179553 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0178781 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0177534 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0176794 |
| QKI | QKI, KH domain containing, RNA binding | 0.0176008 |
| MALT1 | MALT1 paracaspase | 0.0175933 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.275789 |
| APOB | apolipoprotein B | -0.128217 |
| FN1 | fibronectin 1 | -0.109533 |
| EHBP1 | EH domain binding protein 1 | -0.0970884 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0949094 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0946081 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0930904 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0824304 |
| AHSG | alpha-2-HS-glycoprotein | -0.0757527 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0735641 |
| RBM39 | RNA binding motif protein 39 | -0.0726063 |
| TMEM123 | transmembrane protein 123 | -0.0722423 |
| GPC3 | glypican 3 | -0.0706718 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0652769 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0648182 |
| TRIM26 | tripartite motif containing 26 | -0.0623887 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0607932 |
| CP | ceruloplasmin (ferroxidase) | -0.058701 |
| RPS6 | ribosomal protein S6 | -0.0581936 |
| PTCHD4 | patched domain containing 4 | -0.0577561 |
| A2M | alpha-2-macroglobulin | -0.0560354 |
| APOE | apolipoprotein E | -0.0557992 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0553292 |
| PEG10 | paternally expressed 10 | -0.054308 |
| TF | transferrin | -0.0532228 |
| RASGRF2 | Ras protein-specific guanine nucleotide-releasing factor 2 | -0.0529817 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0517806 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0502201 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0498323 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0493952 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0487579 |
| RRBP1 | ribosome binding protein 1 | -0.0485716 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0478054 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0474784 |
| RPS8 | ribosomal protein S8 | -0.0462879 |
| CNKSR3 | CNKSR family member 3 | -0.0457316 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0450626 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0445024 |
| RPL37A | ribosomal protein L37a | -0.0428081 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | -0.0425234 |
| SLC38A1 | solute carrier family 38, member 1 | -0.041942 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.041753 |
| ZFHX3 | zinc finger homeobox 3 | -0.0416176 |
| LYZ | lysozyme | -0.0414716 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0414655 |
| GK | glycerol kinase | -0.0405992 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0400953 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0400401 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.039585 |
| AK1 | adenylate kinase 1 | -0.0381925 |
| FRMD5 | FERM domain containing 5 | -0.038042 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0380085 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0377966 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0377549 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0376938 |
| C3 | complement component 3 | -0.0376342 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.037347 |
| GPC6 | glypican 6 | -0.0371873 |
| MT2A | metallothionein 2A | -0.0366804 |
| FMNL2 | formin-like 2 | -0.0365104 |
| CPE | carboxypeptidase E | -0.0363613 |
| IER3 | immediate early response 3 | -0.0362431 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0357807 |
| APOA1 | apolipoprotein A-I | -0.0354682 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0351792 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0351018 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0347483 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0344159 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0340041 |
| PEG3 | paternally expressed 3 | -0.033736 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0336609 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0333071 |
| SYN3 | synapsin III | -0.0332107 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0326061 |
| MATN3 | matrilin 3 | -0.0324026 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | -0.0320853 |
| RPS19 | ribosomal protein S19 | -0.031237 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0309574 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0309371 |
| RPS27A | ribosomal protein S27a | -0.0307794 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0307321 |
| RACK1 | receptor for activated C kinase 1 | -0.030721 |
| SELENOP | selenoprotein P | -0.0303468 |
| GNAS | GNAS complex locus | -0.030147 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.029849 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.0296949 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0296921 |
| CALR | calreticulin | -0.029243 |
| NHSL1 | NHS-like 1 | -0.0290864 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0290811 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0287899 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.028637 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0283533 |
| ARHGAP18 | Rho GTPase activating protein 18 | -0.0278675 |
| SCN1A | sodium channel, voltage gated, type I alpha subunit | -0.0269883 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0268273 |
| LCOR | ligand dependent nuclear receptor corepressor | -0.0262396 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0262316 |
| ADIPOR2 | adiponectin receptor 2 | -0.0261854 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.0261146 |
