| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clofarabine perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clofarabine_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.15479 |
| MEF2A | myocyte enhancer factor 2A | 0.129457 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.109293 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0952979 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0919176 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0872874 |
| MTSS1 | metastasis suppressor 1 | 0.0829091 |
| PODXL | podocalyxin-like | 0.0795287 |
| NDRG1 | N-myc downstream regulated 1 | 0.077971 |
| MSN | moesin | 0.0778547 |
| ANLN | anillin, actin binding protein | 0.0753775 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.068261 |
| ITGA6 | integrin, alpha 6 | 0.0675068 |
| MYOF | myoferlin | 0.0627833 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0593415 |
| EZR | ezrin | 0.0583708 |
| EFHD2 | EF-hand domain family, member D2 | 0.0558082 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0540743 |
| B2M | beta-2-microglobulin | 0.053923 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0520731 |
| POTEF | POTE ankyrin domain family, member F | 0.051887 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0516963 |
| H1-0 | H1.0 linker histone | 0.0495712 |
| PTMA | prothymosin, alpha | 0.0493281 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0491125 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.048782 |
| SLK | STE20-like kinase | 0.048405 |
| CLU | clusterin | 0.0471479 |
| KRT17 | keratin 17, type I | 0.0467404 |
| MYO10 | myosin X | 0.04626 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0458757 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0456857 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0455146 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0449301 |
| TPM3 | tropomyosin 3 | 0.0436118 |
| BLCAP | bladder cancer associated protein | 0.0435504 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0432911 |
| ARRDC3 | arrestin domain containing 3 | 0.0429862 |
| RTN4 | reticulon 4 | 0.0424272 |
| PGK1 | phosphoglycerate kinase 1 | 0.0417469 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0414927 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0412163 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0410793 |
| ASPH | aspartate beta-hydroxylase | 0.0404194 |
| FOSL1 | FOS-like antigen 1 | 0.0402595 |
| BCL2L1 | BCL2-like 1 | 0.0401333 |
| GOLGA4 | golgin A4 | 0.0388698 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0388018 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0376704 |
| SQLE | squalene epoxidase | 0.0375504 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0373285 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0372139 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0371782 |
| OGA | O-GlcNAcase | 0.0370044 |
| RIN2 | Ras and Rab interactor 2 | 0.0369162 |
| KIAA1217 | KIAA1217 | 0.0362999 |
| ENO1 | enolase 1, (alpha) | 0.0362452 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0357772 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0355951 |
| LDHA | lactate dehydrogenase A | 0.0350114 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0349249 |
| RPS3 | ribosomal protein S3 | 0.0349064 |
| CUL4B | cullin 4B | 0.0348693 |
| AFAP1 | actin filament associated protein 1 | 0.0346729 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0346684 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0345589 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0344348 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0342015 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0341641 |
| ZNF292 | zinc finger protein 292 | 0.0341409 |
| PTK2 | protein tyrosine kinase 2 | 0.034088 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0338615 |
| CENPF | centromere protein F, 350/400kDa | 0.0338395 |
| TPR | translocated promoter region, nuclear basket protein | 0.0335477 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0331042 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0330555 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.032995 |
| YBX3 | Y box binding protein 3 | 0.0327603 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0324793 |
| CD47 | CD47 molecule | 0.0320059 |
| FAM13A | family with sequence similarity 13, member A | 0.0319513 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0315779 |
| NAV2 | neuron navigator 2 | 0.0315721 |
| KRT14 | keratin 14, type I | 0.0311958 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0311295 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0309658 |
| DSTN | destrin (actin depolymerizing factor) | 0.030575 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0304567 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0303365 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0303094 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0302687 |
| LMNA | lamin A/C | 0.030211 |
| PDGFB | platelet-derived growth factor beta polypeptide | 0.0297158 |
| RPS21 | ribosomal protein S21 | 0.029702 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.029675 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0294408 |
| EMP1 | epithelial membrane protein 1 | 0.0294194 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0292087 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0289807 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0288507 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.195145 |
| PDLIM5 | PDZ and LIM domain 5 | -0.107318 |
| LMO7 | LIM domain 7 | -0.0800751 |
| INTS6 | integrator complex subunit 6 | -0.0744456 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0680766 |
| PALLD | palladin, cytoskeletal associated protein | -0.0674714 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0610521 |
| CD44 | CD44 molecule (Indian blood group) | -0.0604716 |
| HM13 | histocompatibility (minor) 13 | -0.0601646 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0591798 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0570898 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0546892 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0509659 |
| AOPEP | aminopeptidase O (putative) | -0.0499412 |
| OSMR | oncostatin M receptor | -0.0476292 |
| FN1 | fibronectin 1 | -0.0437748 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0432695 |
| EXT1 | exostosin glycosyltransferase 1 | -0.042715 |
| RASAL2 | RAS protein activator like 2 | -0.0419907 |
| CNTNAP3 | contactin associated protein-like 3 | -0.0414978 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0394513 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0382214 |
| VCL | vinculin | -0.0379759 |
| STC1 | stanniocalcin 1 | -0.0374842 |
| IGF2 | insulin-like growth factor 2 | -0.0374495 |
| EGFR | epidermal growth factor receptor | -0.0348622 |
| PRSS23 | protease, serine, 23 | -0.0345279 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0344983 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0342743 |
| HMGA2 | high mobility group AT-hook 2 | -0.0339093 |
| LAMA5 | laminin, alpha 5 | -0.0323333 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0322529 |
| RPS24 | ribosomal protein S24 | -0.0316254 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0308108 |
| RPS25 | ribosomal protein S25 | -0.0305129 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0303949 |
| CDK13 | cyclin-dependent kinase 13 | -0.0299796 |
| SETX | senataxin | -0.0297887 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0295869 |
| CDK6 | cyclin-dependent kinase 6 | -0.0292009 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0286334 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0276028 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0274981 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0270336 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0266256 |
| FOXP1 | forkhead box P1 | -0.026089 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0259516 |
| JMJD1C | jumonji domain containing 1C | -0.0259461 |
| HLA-E | major histocompatibility complex, class I, E | -0.0258055 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0256042 |
| SULF1 | sulfatase 1 | -0.0254932 |
| RPLP1 | ribosomal protein, large, P1 | -0.0250581 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0248827 |
| DGKH | diacylglycerol kinase, eta | -0.0248555 |
| THBD | thrombomodulin | -0.024399 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0239262 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0233393 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0232892 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0229426 |
| GPR176 | G protein-coupled receptor 176 | -0.0226223 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0225536 |
| RPL39 | ribosomal protein L39 | -0.0223753 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0217858 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0213957 |
| DHFR | dihydrofolate reductase | -0.0213811 |
| RCOR1 | REST corepressor 1 | -0.0212838 |
| EGR1 | early growth response 1 | -0.0212084 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0209778 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0209655 |
| EFNA5 | ephrin-A5 | -0.0207995 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.0207491 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.020686 |
| S100A10 | S100 calcium binding protein A10 | -0.020652 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0205792 |
| FOXO1 | forkhead box O1 | -0.0205588 |
| FBXO11 | F-box protein 11 | -0.0204765 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0204256 |
| TRAM1 | translocation associated membrane protein 1 | -0.0198539 |
| GOLGB1 | golgin B1 | -0.0196338 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0195265 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0194142 |
| LYST | lysosomal trafficking regulator | -0.0194089 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0193528 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0193508 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0193371 |
| BPTF | bromodomain PHD finger transcription factor | -0.0193133 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0192974 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0191671 |
| SLC30A7 | solute carrier family 30 (zinc transporter), member 7 | -0.0189095 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0187861 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0186925 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0186774 |
| KLF12 | Kruppel-like factor 12 | -0.0185542 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0182455 |
| MECOM | MDS1 and EVI1 complex locus | -0.0181701 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0181243 |
| PLS3 | plastin 3 | -0.0179554 |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa | -0.0179098 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0178715 |
| CMIP | c-Maf inducing protein | -0.017706 |
