| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clofarabine perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clofarabine_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | 0.253311 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.139557 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0735827 |
| RPS3 | ribosomal protein S3 | 0.0673501 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.064079 |
| GOLGA4 | golgin A4 | 0.0627495 |
| ANLN | anillin, actin binding protein | 0.0618797 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0612683 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0609867 |
| H1-0 | H1.0 linker histone | 0.0592528 |
| HYOU1 | hypoxia up-regulated 1 | 0.0569225 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0553229 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0529899 |
| RBM39 | RNA binding motif protein 39 | 0.0503092 |
| AHNAK | AHNAK nucleoprotein | 0.0496431 |
| TMF1 | TATA element modulatory factor 1 | 0.0486217 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0483434 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0479886 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0476615 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0448287 |
| RPS6 | ribosomal protein S6 | 0.0419347 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0419275 |
| PTMA | prothymosin, alpha | 0.0418408 |
| FAM13A | family with sequence similarity 13, member A | 0.0411395 |
| ZNF292 | zinc finger protein 292 | 0.0394158 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0383135 |
| GOLGB1 | golgin B1 | 0.0379925 |
| OGA | O-GlcNAcase | 0.0377239 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0376137 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0373698 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0365676 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0360231 |
| DSPP | dentin sialophosphoprotein | 0.0355382 |
| TMSB4X | thymosin beta 4, X-linked | 0.0353846 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0348299 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0345476 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0344261 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0342215 |
| EZR | ezrin | 0.033742 |
| TES | testin LIM domain protein | 0.0324422 |
| ATXN1 | ataxin 1 | 0.0323503 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0321368 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0318908 |
| LAMB3 | laminin, beta 3 | 0.0317924 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.031562 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0314732 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0304758 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.030254 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0298266 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0298032 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0297747 |
| SERINC1 | serine incorporator 1 | 0.0297074 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0295184 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.029034 |
| AFDN | afadin, adherens junction formation factor | 0.0287878 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.028658 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0285342 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0285291 |
| CLTC | clathrin, heavy chain (Hc) | 0.028481 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0283725 |
| TPD52 | tumor protein D52 | 0.0277673 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0275935 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0275788 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0270723 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0268049 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0263908 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0263782 |
| TXNRD1 | thioredoxin reductase 1 | 0.0262705 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0261786 |
| SET | SET nuclear proto-oncogene | 0.0258469 |
| HMGB2 | high mobility group box 2 | 0.0255606 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0251043 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0249962 |
| RPS2 | ribosomal protein S2 | 0.024307 |
| PREPL | prolyl endopeptidase-like | 0.0241985 |
| CCNY | cyclin Y | 0.0237143 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0236995 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0236622 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0231532 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0230995 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0230013 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0229339 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.0228437 |
| CTTN | cortactin | 0.0226844 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.022515 |
| MORF4L2 | mortality factor 4 like 2 | 0.0223111 |
| RPL37A | ribosomal protein L37a | 0.0222348 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0222241 |
| RPL26 | ribosomal protein L26 | 0.0221885 |
| YEATS2 | YEATS domain containing 2 | 0.0221222 |
| EMP1 | epithelial membrane protein 1 | 0.0220682 |
| PMM2 | phosphomannomutase 2 | 0.0219867 |
| SPAG9 | sperm associated antigen 9 | 0.0219671 |
| ARF4 | ADP-ribosylation factor 4 | 0.0219295 |
| EPN2 | epsin 2 | 0.0218738 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0217782 |
| RAB6A | RAB6A, member RAS oncogene family | 0.021731 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.021671 |
| NKTR | natural killer cell triggering receptor | 0.0216485 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0215284 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GMDS | GDP-mannose 4,6-dehydratase | -0.148287 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.104762 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.102074 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0908611 |
| LMO7 | LIM domain 7 | -0.074946 |
| NPSR1 | neuropeptide S receptor 1 | -0.0649107 |
| TMEM123 | transmembrane protein 123 | -0.0559951 |
| MYO1E | myosin IE | -0.0518726 |
| PLSCR1 | phospholipid scramblase 1 | -0.0513712 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0512705 |
| RNF213 | ring finger protein 213 | -0.0495372 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0485138 |
| EHBP1 | EH domain binding protein 1 | -0.0474308 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.046956 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0455105 |
| TMSB10 | thymosin beta 10 | -0.0453116 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0426974 |
| CDK6 | cyclin-dependent kinase 6 | -0.0425845 |
| PKM | pyruvate kinase, muscle | -0.042302 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0420816 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0410233 |
| MUC17 | mucin 17, cell surface associated | -0.0407449 |
| S100A6 | S100 calcium binding protein A6 | -0.0403576 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0401507 |
| POTEF | POTE ankyrin domain family, member F | -0.0386746 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0383984 |
| GPX2 | glutathione peroxidase 2 | -0.0361087 |
| MCU | mitochondrial calcium uniporter | -0.0352973 |
| S100A10 | S100 calcium binding protein A10 | -0.0350667 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0340613 |
| COBL | cordon-bleu WH2 repeat protein | -0.0334936 |
| RPLP1 | ribosomal protein, large, P1 | -0.0333549 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.032829 |
| CUX1 | cut-like homeobox 1 | -0.0326436 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0324947 |
| RPS25 | ribosomal protein S25 | -0.0321703 |
| SP100 | SP100 nuclear antigen | -0.0319923 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0319801 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0317515 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0309612 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0299528 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.029903 |
| ABLIM1 | actin binding LIM protein 1 | -0.0294543 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.0291729 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0289603 |
| BPTF | bromodomain PHD finger transcription factor | -0.0289299 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.0286696 |
| RPS24 | ribosomal protein S24 | -0.0285094 |
| HMGA1 | high mobility group AT-hook 1 | -0.0284592 |
| PHF14 | PHD finger protein 14 | -0.02826 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0281106 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0278904 |
| TJP1 | tight junction protein 1 | -0.0278404 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0276829 |
| RUNX1 | runt-related transcription factor 1 | -0.0270377 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0269096 |
| PRKCA | protein kinase C, alpha | -0.026829 |
| AGR2 | anterior gradient 2 | -0.0268105 |
| PRSS3 | protease, serine, 3 | -0.0267134 |
| SIK3 | SIK family kinase 3 | -0.0266034 |
| INTS6 | integrator complex subunit 6 | -0.0266003 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0265126 |
| HLA-A | major histocompatibility complex, class I, A | -0.026298 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0259674 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0257767 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0254809 |
| CLDN4 | claudin 4 | -0.025459 |
| POF1B | premature ovarian failure, 1B | -0.0252783 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.024952 |
| MUC1 | mucin 1, cell surface associated | -0.0245461 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0244027 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0243597 |
| AHR | aryl hydrocarbon receptor | -0.0242687 |
| SULF2 | sulfatase 2 | -0.0242568 |
| MX1 | MX dynamin-like GTPase 1 | -0.0240292 |
| INSIG1 | insulin induced gene 1 | -0.0240219 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -0.023849 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0237395 |
| TCF12 | transcription factor 12 | -0.0236059 |
| RASAL2 | RAS protein activator like 2 | -0.0235839 |
| HLA-E | major histocompatibility complex, class I, E | -0.0234905 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0232343 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0232044 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0231778 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0230993 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0227357 |
| TMC5 | transmembrane channel-like 5 | -0.0227279 |
| PKP4 | plakophilin 4 | -0.0226632 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0224365 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0223749 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0223171 |
| MX2 | MX dynamin-like GTPase 2 | -0.0222369 |
| FASN | fatty acid synthase | -0.02209 |
| RIGI | RNA sensor RIG-I | -0.0219957 |
| PITPNB | phosphatidylinositol transfer protein, beta | -0.0219304 |
| SH3D19 | SH3 domain containing 19 | -0.0218003 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0215292 |
| GDA | guanine deaminase | -0.0215234 |
| TTYH3 | tweety family member 3 | -0.0215123 |
| AOPEP | aminopeptidase O (putative) | -0.021489 |
