| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clofarabine perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clofarabine_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.187221 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.117042 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.107957 |
| FAM13A | family with sequence similarity 13, member A | 0.0958152 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0925562 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0786965 |
| PTMA | prothymosin, alpha | 0.077683 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0716642 |
| SMAD3 | SMAD family member 3 | 0.0712852 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0706279 |
| MT2A | metallothionein 2A | 0.068831 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0685431 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0676212 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0668644 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0527064 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0523554 |
| B2M | beta-2-microglobulin | 0.0496635 |
| RPS3 | ribosomal protein S3 | 0.0496437 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0495678 |
| RPS6 | ribosomal protein S6 | 0.049402 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0482586 |
| ENO1 | enolase 1, (alpha) | 0.0480853 |
| TMSB10 | thymosin beta 10 | 0.0477856 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0469805 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0466447 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.045194 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0438918 |
| FLNB | filamin B, beta | 0.0436269 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0432582 |
| PRELID2 | PRELI domain containing 2 | 0.0432529 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0428738 |
| RPS12 | ribosomal protein S12 | 0.0428326 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0427602 |
| ANGPTL4 | angiopoietin-like 4 | 0.0423584 |
| AHNAK | AHNAK nucleoprotein | 0.0419394 |
| TMSB4X | thymosin beta 4, X-linked | 0.0415851 |
| FAM107B | family with sequence similarity 107, member B | 0.0411229 |
| RPS19 | ribosomal protein S19 | 0.0409414 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0408789 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0403919 |
| RPL37A | ribosomal protein L37a | 0.0401995 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0399683 |
| NGLY1 | N-glycanase 1 | 0.0399287 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0388118 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0384326 |
| H1-0 | H1.0 linker histone | 0.0373865 |
| RPS8 | ribosomal protein S8 | 0.0368942 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0368037 |
| APP | amyloid beta (A4) precursor protein | 0.0367389 |
| FTL | ferritin, light polypeptide | 0.0365735 |
| RIOK3 | RIO kinase 3 | 0.0363326 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0357075 |
| RPS21 | ribosomal protein S21 | 0.0355615 |
| NAV2 | neuron navigator 2 | 0.0353528 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0352128 |
| MTSS1 | metastasis suppressor 1 | 0.0347678 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0344271 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0335464 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0334492 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0330158 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0329806 |
| RPL11 | ribosomal protein L11 | 0.0323754 |
| PTK2 | protein tyrosine kinase 2 | 0.0322854 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.031952 |
| MEF2A | myocyte enhancer factor 2A | 0.0319055 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0316098 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0311682 |
| OGA | O-GlcNAcase | 0.0307756 |
| ADD3 | adducin 3 (gamma) | 0.0303087 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0302564 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.030235 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0300373 |
| RARB | retinoic acid receptor, beta | 0.0297856 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0297356 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.029357 |
| ASPH | aspartate beta-hydroxylase | 0.0288728 |
| RPL4 | ribosomal protein L4 | 0.028696 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0285778 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0282606 |
| RPL36 | ribosomal protein L36 | 0.0281602 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.02791 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0278591 |
| RPL32 | ribosomal protein L32 | 0.0276209 |
| LDHA | lactate dehydrogenase A | 0.0275913 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0275824 |
| CDCP1 | CUB domain containing protein 1 | 0.0275103 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0272863 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0268343 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0265862 |
| KIF5B | kinesin family member 5B | 0.0265528 |
| FAM20C | family with sequence similarity 20, member C | 0.0265504 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0265084 |
| RPL23 | ribosomal protein L23 | 0.0263409 |
| RPL34 | ribosomal protein L34 | 0.0263331 |
| SFTPA2 | surfactant protein A2 | 0.0262813 |
| RPL35A | ribosomal protein L35a | 0.0262748 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0261871 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0260904 |
| RPS17 | ribosomal protein S17 | 0.0257931 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0257589 |
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.116216 |
| LOX | lysyl oxidase | -0.0998444 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0985853 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0823841 |
| CD44 | CD44 molecule (Indian blood group) | -0.0765452 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0727679 |
| USP34 | ubiquitin specific peptidase 34 | -0.0717445 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0690014 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0668671 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.066214 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0617588 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0596006 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0594012 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0550347 |
| EGR1 | early growth response 1 | -0.0548531 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0540539 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0513345 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0504162 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0501379 |
| COPA | coatomer protein complex, subunit alpha | -0.0485338 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0476182 |
| BPTF | bromodomain PHD finger transcription factor | -0.0474596 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.046465 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0464631 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0462683 |
| GLCCI1 | glucocorticoid induced 1 | -0.0448993 |
| AADAC | arylacetamide deacetylase | -0.0445269 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0430428 |
| OSMR | oncostatin M receptor | -0.0429268 |
| HM13 | histocompatibility (minor) 13 | -0.0423016 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0422465 |
| VMP1 | vacuole membrane protein 1 | -0.0419196 |
| TNNC1 | troponin C type 1 (slow) | -0.0415575 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0408662 |
| GOLGA4 | golgin A4 | -0.0406275 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0405094 |
| SEC24A | SEC24 family member A | -0.0401418 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0400838 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0399671 |
| NTN4 | netrin 4 | -0.0389133 |
| EHBP1 | EH domain binding protein 1 | -0.038224 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0373945 |
| NF1 | neurofibromin 1 | -0.0370381 |
| ARF4 | ADP-ribosylation factor 4 | -0.0367022 |
| EGFR | epidermal growth factor receptor | -0.0363002 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0345864 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0345515 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0342004 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0340796 |
| IL1R1 | interleukin 1 receptor, type I | -0.0338268 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0335296 |
| SCFD1 | sec1 family domain containing 1 | -0.0330971 |
| SRP54 | signal recognition particle 54kDa | -0.0329473 |
| RNF24 | ring finger protein 24 | -0.0318172 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0316356 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0313353 |
| HMGA2 | high mobility group AT-hook 2 | -0.0311903 |
| ATF7 | activating transcription factor 7 | -0.0310361 |
| SYT1 | synaptotagmin I | -0.0300564 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.0297343 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0296953 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0296134 |
| VIM | vimentin | -0.0295889 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0295294 |
| VRK2 | vaccinia related kinase 2 | -0.0294743 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0293639 |
| HDLBP | high density lipoprotein binding protein | -0.0293479 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0291111 |
| ZNF609 | zinc finger protein 609 | -0.0289344 |
| GPATCH2L | G patch domain containing 2-like | -0.0284239 |
| DENND4A | DENN/MADD domain containing 4A | -0.0283706 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0282207 |
| MYADM | myeloid-associated differentiation marker | -0.0281288 |
| CALU | calumenin | -0.0280217 |
| YME1L1 | YME1-like 1 ATPase | -0.0277313 |
| ATM | ATM serine/threonine kinase | -0.0274795 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0273756 |
| FNIP1 | folliculin interacting protein 1 | -0.0272189 |
| NABP1 | nucleic acid binding protein 1 | -0.0271625 |
| KYNU | kynureninase | -0.0270961 |
| LRRC49 | leucine rich repeat containing 49 | -0.0269667 |
| NCOA7 | nuclear receptor coactivator 7 | -0.026827 |
| CDK13 | cyclin-dependent kinase 13 | -0.0268202 |
| MCL1 | myeloid cell leukemia 1 | -0.0262797 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0258242 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0256727 |
| ATG7 | autophagy related 7 | -0.02567 |
| KSR1 | kinase suppressor of ras 1 | -0.0255966 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0254631 |
| MYO9A | myosin IXA | -0.0250341 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.024937 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0249172 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0248258 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0246881 |
| WASF2 | WAS protein family, member 2 | -0.0242261 |
| GOLGA3 | golgin A3 | -0.0241801 |
| MORF4L2 | mortality factor 4 like 2 | -0.0237278 |
| GLIS3 | GLIS family zinc finger 3 | -0.0235938 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0231693 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0230732 |
