| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clofarabine perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clofarabine_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.103747 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0978296 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0928277 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0820603 |
| PTMA | prothymosin, alpha | 0.0749408 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0735503 |
| TPM3 | tropomyosin 3 | 0.0701981 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0643345 |
| RPS3 | ribosomal protein S3 | 0.0632556 |
| TXNRD1 | thioredoxin reductase 1 | 0.0566898 |
| RPS2 | ribosomal protein S2 | 0.0505549 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0502154 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0487673 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0479666 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0463951 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0459896 |
| RPS6 | ribosomal protein S6 | 0.0442612 |
| RPL4 | ribosomal protein L4 | 0.0435143 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0403195 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.040025 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0399917 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0391347 |
| WDR43 | WD repeat domain 43 | 0.0375012 |
| CANX | calnexin | 0.0345814 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0343742 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0342919 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0342526 |
| MKI67 | marker of proliferation Ki-67 | 0.0337019 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0336031 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0335984 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0334392 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0326989 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0319186 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0318629 |
| KIF5B | kinesin family member 5B | 0.0311028 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0310464 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0309446 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0307654 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0305782 |
| SFTPA2 | surfactant protein A2 | 0.0305105 |
| YBX1 | Y box binding protein 1 | 0.0303671 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0301763 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0299447 |
| CHN1 | chimerin 1 | 0.0296911 |
| CAVIN1 | caveolae associated protein 1 | 0.0295477 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0292449 |
| YBX3 | Y box binding protein 3 | 0.0288728 |
| WBP11 | WW domain binding protein 11 | 0.0287734 |
| TPD52 | tumor protein D52 | 0.0286129 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0285468 |
| HDGF | hepatoma-derived growth factor | 0.0276553 |
| PNN | pinin, desmosome associated protein | 0.0275846 |
| SET | SET nuclear proto-oncogene | 0.0275539 |
| ANXA1 | annexin A1 | 0.0272607 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0271631 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0271119 |
| RTN4 | reticulon 4 | 0.0267884 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0264613 |
| KLF6 | Kruppel-like factor 6 | 0.0263635 |
| YME1L1 | YME1-like 1 ATPase | 0.0260685 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0260511 |
| ANLN | anillin, actin binding protein | 0.0258964 |
| CENPF | centromere protein F, 350/400kDa | 0.0257347 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.025514 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.025442 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0253527 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0251262 |
| SRGN | serglycin | 0.0251221 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.025062 |
| RPL26 | ribosomal protein L26 | 0.0249927 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0246748 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0245838 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0244652 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0242182 |
| RPS12 | ribosomal protein S12 | 0.0241005 |
| RPL14 | ribosomal protein L14 | 0.0239678 |
| TMSB4X | thymosin beta 4, X-linked | 0.0231046 |
| GOLT1B | golgi transport 1B | 0.0231037 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0224269 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.022308 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0222514 |
| BRIX1 | BRX1, biogenesis of ribosomes | 0.0222126 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0220853 |
| ZNF292 | zinc finger protein 292 | 0.0217566 |
| RBM8A | RNA binding motif protein 8A | 0.0216724 |
| ASPH | aspartate beta-hydroxylase | 0.0215139 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0215007 |
| CASC3 | cancer susceptibility candidate 3 | 0.0212839 |
| USP3 | ubiquitin specific peptidase 3 | 0.0210145 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0209839 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0209774 |
| JAK1 | Janus kinase 1 | 0.0206772 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0204743 |
| RPS7 | ribosomal protein S7 | 0.0202396 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0202348 |
| FGB | fibrinogen beta chain | 0.0201699 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0201627 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.0200424 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0199952 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.019902 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.277788 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.190666 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.174593 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.14173 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.124508 |
| FTL | ferritin, light polypeptide | -0.110773 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.108246 |
| TMSB10 | thymosin beta 10 | -0.100947 |
| PARD3 | par-3 family cell polarity regulator | -0.0795937 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0740569 |
| IGF2 | insulin-like growth factor 2 | -0.0679478 |
| CMIP | c-Maf inducing protein | -0.0675042 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0654146 |
| USP34 | ubiquitin specific peptidase 34 | -0.0639629 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0625173 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0614037 |
| VIM | vimentin | -0.0607294 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0604796 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.058108 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0560765 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0558441 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0529862 |
| SVIL | supervillin | -0.0526389 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.05244 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0521825 |
| EGFR | epidermal growth factor receptor | -0.0513943 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0504998 |
| RPLP1 | ribosomal protein, large, P1 | -0.0497633 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0494604 |
| GRAMD1B | GRAM domain containing 1B | -0.0490985 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0490334 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0480137 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0454047 |
| NEGR1 | neuronal growth regulator 1 | -0.0448139 |
| KYNU | kynureninase | -0.0443556 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0432172 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0425583 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0415919 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0389396 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0381357 |
| WWOX | WW domain containing oxidoreductase | -0.0380673 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0379393 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0375243 |
| MCL1 | myeloid cell leukemia 1 | -0.0374725 |
| ACTG1 | actin gamma 1 | -0.0370821 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0359595 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0358769 |
| NF1 | neurofibromin 1 | -0.0356448 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0349238 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0348951 |
| GLIS3 | GLIS family zinc finger 3 | -0.0348797 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0346631 |
| BICC1 | BicC family RNA binding protein 1 | -0.0340643 |
| RAD51B | RAD51 paralog B | -0.0336579 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0334926 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0323938 |
| EGR1 | early growth response 1 | -0.0319205 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0318137 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0310358 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0307301 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0305849 |
| ATXN1 | ataxin 1 | -0.0303106 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0302833 |
| CUX1 | cut-like homeobox 1 | -0.0301488 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0299378 |
| STC1 | stanniocalcin 1 | -0.029688 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0292149 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0291615 |
| EHBP1 | EH domain binding protein 1 | -0.0287449 |
| RPS20 | ribosomal protein S20 | -0.0286341 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0285487 |
| CREBBP | CREB binding protein | -0.0284858 |
| IER3 | immediate early response 3 | -0.0284286 |
| INTS6 | integrator complex subunit 6 | -0.0284139 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0284053 |
| COPA | coatomer protein complex, subunit alpha | -0.0282704 |
| CDK13 | cyclin-dependent kinase 13 | -0.0280894 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0278836 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0278505 |
| BRD2 | bromodomain containing 2 | -0.0277352 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0277257 |
| EXOC6B | exocyst complex component 6B | -0.0275206 |
| FBXO11 | F-box protein 11 | -0.0273105 |
| DST | dystonin | -0.027213 |
| RPS16 | ribosomal protein S16 | -0.0271769 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0271327 |
| PTK2 | protein tyrosine kinase 2 | -0.0270821 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0270573 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0270111 |
| RASAL2 | RAS protein activator like 2 | -0.0269762 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0265943 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.026516 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0264366 |
| PFN1 | profilin 1 | -0.0260588 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0260161 |
| NBEAL1 | neurobeachin-like 1 | -0.0256094 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0255822 |
| NRG1 | neuregulin 1 | -0.0255797 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0254896 |
| MED13 | mediator complex subunit 13 | -0.0253083 |
