| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clofarabine perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clofarabine_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.191918 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.180745 |
| NPTN | neuroplastin | 0.106875 |
| RPS3 | ribosomal protein S3 | 0.0995929 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0972091 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0956336 |
| ANXA1 | annexin A1 | 0.0937191 |
| RBM39 | RNA binding motif protein 39 | 0.0868864 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0836972 |
| NCKAP1 | NCK-associated protein 1 | 0.0720621 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0658053 |
| TSC22D2 | TSC22 domain family, member 2 | 0.063227 |
| HDLBP | high density lipoprotein binding protein | 0.0619861 |
| PTK2 | protein tyrosine kinase 2 | 0.0608985 |
| HELZ | helicase with zinc finger | 0.0602698 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0597713 |
| CLINT1 | clathrin interactor 1 | 0.0564944 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0560227 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0560219 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0553084 |
| DSCAM | Down syndrome cell adhesion molecule | 0.053703 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0536139 |
| FAM13A | family with sequence similarity 13, member A | 0.0517976 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0508649 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0506688 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0504672 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0501286 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.0492108 |
| MYOF | myoferlin | 0.0489176 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0484561 |
| JAK2 | Janus kinase 2 | 0.0482208 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0477554 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0471022 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0468983 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0465675 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0461308 |
| CUL3 | cullin 3 | 0.045858 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0455462 |
| HYOU1 | hypoxia up-regulated 1 | 0.0453968 |
| CDCP1 | CUB domain containing protein 1 | 0.0451473 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0445257 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0445049 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0443988 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0443542 |
| IFI44 | interferon-induced protein 44 | 0.0428045 |
| RPS6 | ribosomal protein S6 | 0.042534 |
| TCP11L2 | t-complex 11, testis-specific-like 2 | 0.041997 |
| TFG | TRK-fused gene | 0.041849 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0415912 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 | 0.0413533 |
| RPL5 | ribosomal protein L5 | 0.041055 |
| USP3 | ubiquitin specific peptidase 3 | 0.0401783 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0398075 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0397857 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0397717 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0394599 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0393386 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0392838 |
| CSNK2A2 | casein kinase 2, alpha prime polypeptide | 0.0390287 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.038437 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0380889 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0379392 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0376132 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0371131 |
| PTMA | prothymosin, alpha | 0.0371 |
| NBEAL1 | neurobeachin-like 1 | 0.0370169 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0367679 |
| GOLGA4 | golgin A4 | 0.0366438 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0363937 |
| RPL37A | ribosomal protein L37a | 0.0361901 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0361072 |
| TXNIP | thioredoxin interacting protein | 0.0359651 |
| RYBP | RING1 and YY1 binding protein | 0.0355658 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0352827 |
| PCMTD1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | 0.0352742 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0346933 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0343504 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0337991 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0334448 |
| PDE10A | phosphodiesterase 10A | 0.0331825 |
| ZNF638 | zinc finger protein 638 | 0.0331125 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0330752 |
| RDX | radixin | 0.0329337 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0328657 |
| STK24 | serine/threonine kinase 24 | 0.0327923 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0326855 |
| ARRDC3 | arrestin domain containing 3 | 0.032588 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0325692 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0323218 |
| RPL11 | ribosomal protein L11 | 0.0322623 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0321558 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0320766 |
| CCNY | cyclin Y | 0.0319047 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0316615 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0313925 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0313391 |
| KLC1 | kinesin light chain 1 | 0.0313332 |
| AFTPH | aftiphilin | 0.0312708 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0310552 |
| OGA | O-GlcNAcase | 0.030896 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | -0.162494 |
| VIM | vimentin | -0.146754 |
| PARD3 | par-3 family cell polarity regulator | -0.134748 |
| FN1 | fibronectin 1 | -0.131422 |
| STC1 | stanniocalcin 1 | -0.109005 |
| GPC6 | glypican 6 | -0.107813 |
| LSAMP | limbic system-associated membrane protein | -0.10152 |
| KYNU | kynureninase | -0.100892 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0866058 |
| RAB10 | RAB10, member RAS oncogene family | -0.0855228 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0850695 |
| ENO1 | enolase 1, (alpha) | -0.0808898 |
| TMSB10 | thymosin beta 10 | -0.080865 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0808354 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0769417 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0767065 |
| INHBA | inhibin, beta A | -0.0759605 |
| CUX1 | cut-like homeobox 1 | -0.0746883 |
| TJP1 | tight junction protein 1 | -0.0734481 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0731335 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0730638 |
| EGR1 | early growth response 1 | -0.0719669 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0715205 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0707549 |
| LAMB3 | laminin, beta 3 | -0.0705629 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0699132 |
| SMYD3 | SET and MYND domain containing 3 | -0.069042 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0675417 |
| MORF4L2 | mortality factor 4 like 2 | -0.0665602 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0642468 |
| SPAG9 | sperm associated antigen 9 | -0.0640287 |
| FMNL2 | formin-like 2 | -0.0635532 |
| TNPO1 | transportin 1 | -0.0623428 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0620104 |
| KRT17 | keratin 17, type I | -0.0616254 |
| MSN | moesin | -0.0613275 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0609081 |
| FTL | ferritin, light polypeptide | -0.0600486 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.058946 |
| B2M | beta-2-microglobulin | -0.0577876 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0566087 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0561154 |
| ACTG1 | actin gamma 1 | -0.0534602 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.052784 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0526912 |
| LDHA | lactate dehydrogenase A | -0.0525966 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.051725 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.051688 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0506233 |
| ANXA2 | annexin A2 | -0.0503445 |
| S100A10 | S100 calcium binding protein A10 | -0.0497613 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0484764 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0464691 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0456994 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0436053 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0433669 |
| AK1 | adenylate kinase 1 | -0.0433612 |
| PRKCA | protein kinase C, alpha | -0.0421914 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0417472 |
| MED13 | mediator complex subunit 13 | -0.0416875 |
| VMP1 | vacuole membrane protein 1 | -0.0416481 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0411604 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0402129 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0393887 |
| CD44 | CD44 molecule (Indian blood group) | -0.0391077 |
| MT2A | metallothionein 2A | -0.038752 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.036849 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0366581 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0364907 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.035907 |
| BBX | bobby sox homolog (Drosophila) | -0.0356778 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0353057 |
| MCL1 | myeloid cell leukemia 1 | -0.0348236 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0348029 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.033794 |
| ARF1 | ADP-ribosylation factor 1 | -0.0328242 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.032771 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0325121 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0325054 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0324231 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0321306 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0321064 |
| RRBP1 | ribosome binding protein 1 | -0.0320778 |
| ASPH | aspartate beta-hydroxylase | -0.0320449 |
| SQSTM1 | sequestosome 1 | -0.0316604 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | -0.0315083 |
| ZNF609 | zinc finger protein 609 | -0.0313491 |
| INTS6 | integrator complex subunit 6 | -0.0308538 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0308454 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0307873 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0301171 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0295314 |
| MXD1 | MAX dimerization protein 1 | -0.0292027 |
| NFIA | nuclear factor I/A | -0.0290846 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0289635 |
| DIAPH1 | diaphanous-related formin 1 | -0.028885 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0284465 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0284359 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0283789 |
| FLNB | filamin B, beta | -0.0283346 |
