| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clofarabine perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clofarabine_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.164226 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.154936 |
| H1-4 | H1.4 linker histone, cluster member | 0.0920259 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0794853 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0747575 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0649117 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0630818 |
| COL3A1 | collagen, type III, alpha 1 | 0.0613005 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0579275 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0540097 |
| UPP1 | uridine phosphorylase 1 | 0.0532117 |
| RPL26 | ribosomal protein L26 | 0.0515405 |
| PTMA | prothymosin, alpha | 0.0507074 |
| RPS2 | ribosomal protein S2 | 0.050066 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0495808 |
| MKI67 | marker of proliferation Ki-67 | 0.0486822 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0471654 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0461523 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0428594 |
| ANXA1 | annexin A1 | 0.0410678 |
| H1-2 | H1.2 linker histone, cluster member | 0.0409951 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0400472 |
| THBS1 | thrombospondin 1 | 0.0394164 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0393385 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0391608 |
| RPL37 | ribosomal protein L37 | 0.0387877 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0384512 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0380899 |
| TMSB4X | thymosin beta 4, X-linked | 0.0380274 |
| MB21D2 | Mab-21 domain containing 2 | 0.0378832 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0377224 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0372063 |
| MYO10 | myosin X | 0.036668 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0365603 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0362469 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0360354 |
| GPC3 | glypican 3 | 0.0352531 |
| TPM3 | tropomyosin 3 | 0.0352248 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0348176 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0346092 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0343653 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0336898 |
| RPS12 | ribosomal protein S12 | 0.0336361 |
| HMGB2 | high mobility group box 2 | 0.0335109 |
| RPS6 | ribosomal protein S6 | 0.0324588 |
| PLPP1 | phospholipid phosphatase 1 | 0.0323915 |
| CDC73 | cell division cycle 73 | 0.0319364 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0318949 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0317388 |
| CORO1C | coronin, actin binding protein, 1C | 0.0317072 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0316301 |
| TPR | translocated promoter region, nuclear basket protein | 0.0315085 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0314723 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0308025 |
| RPS19 | ribosomal protein S19 | 0.0307882 |
| TPX2 | TPX2, microtubule-associated | 0.0307517 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0306044 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0298981 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0297402 |
| PRPF4B | pre-mRNA processing factor 4B | 0.029733 |
| SET | SET nuclear proto-oncogene | 0.0294766 |
| USP53 | ubiquitin specific peptidase 53 | 0.0289456 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0289034 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0287708 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0286756 |
| NCKAP1 | NCK-associated protein 1 | 0.0285975 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0278603 |
| NPAS3 | neuronal PAS domain protein 3 | 0.0274464 |
| PUM2 | pumilio RNA-binding family member 2 | 0.027163 |
| RHOH | ras homolog family member H | 0.0271452 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0270088 |
| RPL14 | ribosomal protein L14 | 0.0268658 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0268373 |
| RPS3 | ribosomal protein S3 | 0.0267339 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0267124 |
| GOLGB1 | golgin B1 | 0.0266672 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0264912 |
| ZNF292 | zinc finger protein 292 | 0.0264722 |
| KIF5B | kinesin family member 5B | 0.0262756 |
| EFNA5 | ephrin-A5 | 0.0261284 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0260492 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0259236 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0258758 |
| JMJD1C | jumonji domain containing 1C | 0.0256253 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0253908 |
| RPS27A | ribosomal protein S27a | 0.0253692 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.025295 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0252813 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0252562 |
| RBM39 | RNA binding motif protein 39 | 0.0250703 |
| HDAC2 | histone deacetylase 2 | 0.0249266 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0245381 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0244983 |
| ADAR | adenosine deaminase, RNA-specific | 0.0243565 |
| CFL2 | cofilin 2 (muscle) | 0.0242107 |
| TENM2 | teneurin transmembrane protein 2 | 0.0239938 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0237925 |
| OGA | O-GlcNAcase | 0.0237541 |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit | 0.0237147 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0234893 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.131632 |
| PEG10 | paternally expressed 10 | -0.0918593 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0895326 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0828331 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.077891 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0651569 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0644005 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0633064 |
| PFN1 | profilin 1 | -0.0518296 |
| RAD51B | RAD51 paralog B | -0.0515653 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0512081 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0505848 |
| TUBA1B | tubulin, alpha 1b | -0.0495738 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0482472 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0480689 |
| COL1A2 | collagen, type I, alpha 2 | -0.0480531 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0477735 |
| PHIP | pleckstrin homology domain interacting protein | -0.0475556 |
| POTEF | POTE ankyrin domain family, member F | -0.0470139 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0451618 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.04471 |
| SRP54 | signal recognition particle 54kDa | -0.0425799 |
| R3HDM1 | R3H domain containing 1 | -0.0424686 |
| FBXO17 | F-box protein 17 | -0.0421393 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0411549 |
| LYST | lysosomal trafficking regulator | -0.0408964 |
| SETD5 | SET domain containing 5 | -0.0401748 |
| FBXO11 | F-box protein 11 | -0.0391912 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0386966 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0384379 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0383324 |
| NOP58 | NOP58 ribonucleoprotein | -0.0379683 |
| CAPNS1 | calpain, small subunit 1 | -0.0376818 |
| COL11A1 | collagen, type XI, alpha 1 | -0.037517 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0374192 |
| ERBIN | erbb2 interacting protein | -0.0374134 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0368853 |
| USP34 | ubiquitin specific peptidase 34 | -0.0366343 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0366006 |
| RAB10 | RAB10, member RAS oncogene family | -0.036207 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.036168 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.036148 |
| FAM171B | family with sequence similarity 171, member B | -0.0354031 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0352946 |
| MEIS2 | Meis homeobox 2 | -0.0352066 |
| GNAS | GNAS complex locus | -0.0352047 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0347456 |
| PRR16 | proline rich 16 | -0.034744 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0343962 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0341899 |
| NEBL | nebulette | -0.034087 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0337019 |
| TENM3 | teneurin transmembrane protein 3 | -0.0334868 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0331829 |
| SYT1 | synaptotagmin I | -0.0330594 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0321801 |
| CADM2 | cell adhesion molecule 2 | -0.0314497 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.030564 |
| PRORP | protein only RNase P catalytic subunit | -0.0305574 |
| RPS16 | ribosomal protein S16 | -0.0304939 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0303384 |
| EMP1 | epithelial membrane protein 1 | -0.0302099 |
| BSG | basigin (Ok blood group) | -0.0301065 |
| GOLIM4 | golgi integral membrane protein 4 | -0.0300119 |
| PGK1 | phosphoglycerate kinase 1 | -0.029758 |
| NXN | nucleoredoxin | -0.0293841 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0292748 |
| MPG | N-methylpurine-DNA glycosylase | -0.0290676 |
| DMD | dystrophin | -0.0290633 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0288234 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0287066 |
| PHF21A | PHD finger protein 21A | -0.0284923 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0283917 |
| TOR1AIP2 | torsin A interacting protein 2 | -0.0283868 |
| GARRE1 | granule associated Rac and RHOG effector 1 | -0.0283832 |
| CCDC102B | coiled-coil domain containing 102B | -0.0282973 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0282487 |
| CDK13 | cyclin-dependent kinase 13 | -0.0281792 |
| NBEAL1 | neurobeachin-like 1 | -0.0281136 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0280268 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0279989 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0278616 |
| NUP155 | nucleoporin 155kDa | -0.0271211 |
| CDH19 | cadherin 19, type 2 | -0.0270129 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0270027 |
| GLG1 | golgi glycoprotein 1 | -0.0269967 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0268495 |
| MAP4 | microtubule-associated protein 4 | -0.0262942 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.0262794 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0262699 |
| CBX1 | chromobox homolog 1 | -0.0262601 |
| RPLP1 | ribosomal protein, large, P1 | -0.026254 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0262296 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.025843 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0256066 |
| TMEM123 | transmembrane protein 123 | -0.0255732 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0254095 |
| TMSB10 | thymosin beta 10 | -0.0251675 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0251116 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0250507 |
