| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clofarabine perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clofarabine_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.178109 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.168145 |
| RPS3 | ribosomal protein S3 | 0.0952319 |
| RPS12 | ribosomal protein S12 | 0.0918595 |
| MSN | moesin | 0.0909384 |
| TAPBP | TAP binding protein (tapasin) | 0.0892947 |
| RPS6 | ribosomal protein S6 | 0.0875618 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0838154 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0750474 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0736409 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0716818 |
| B2M | beta-2-microglobulin | 0.0714264 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.066985 |
| VEGFA | vascular endothelial growth factor A | 0.0658477 |
| RTN4 | reticulon 4 | 0.0650264 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0645903 |
| MT2A | metallothionein 2A | 0.0645724 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0629751 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0610896 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0603036 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0586242 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0571013 |
| RPS2 | ribosomal protein S2 | 0.0569636 |
| ARRDC3 | arrestin domain containing 3 | 0.0561406 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0549143 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0542354 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0536872 |
| C3 | complement component 3 | 0.0532654 |
| NAV2 | neuron navigator 2 | 0.0531618 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.052958 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0499947 |
| FLNB | filamin B, beta | 0.0462056 |
| MKI67 | marker of proliferation Ki-67 | 0.0461312 |
| CENPF | centromere protein F, 350/400kDa | 0.0456119 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0410081 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0392377 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0391779 |
| ADM | adrenomedullin | 0.0388237 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0369588 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0366791 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0365532 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0358845 |
| RPS8 | ribosomal protein S8 | 0.0356489 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0352808 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0352386 |
| FAM219A | family with sequence similarity 219, member A | 0.0350904 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.034697 |
| PDE10A | phosphodiesterase 10A | 0.0344465 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0334922 |
| SEPTIN9 | septin 9 | 0.0327329 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.032582 |
| LOXL2 | lysyl oxidase-like 2 | 0.0324323 |
| RACK1 | receptor for activated C kinase 1 | 0.0320465 |
| RPS17 | ribosomal protein S17 | 0.03149 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0313975 |
| RPL11 | ribosomal protein L11 | 0.0309757 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0305122 |
| RPS4X | ribosomal protein S4, X-linked | 0.0303576 |
| EZR | ezrin | 0.0303329 |
| PLIN2 | perilipin 2 | 0.0293743 |
| TPM3 | tropomyosin 3 | 0.0291035 |
| RPL37A | ribosomal protein L37a | 0.0290372 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0289728 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.028694 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0285782 |
| FOSL1 | FOS-like antigen 1 | 0.0282453 |
| YBX1 | Y box binding protein 1 | 0.0281476 |
| RND3 | Rho family GTPase 3 | 0.0277042 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0275295 |
| SFTPA2 | surfactant protein A2 | 0.027496 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0273734 |
| ZNF395 | zinc finger protein 395 | 0.0271617 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0270758 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0268292 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.026703 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0264173 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0263108 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0261963 |
| CALD1 | caldesmon 1 | 0.0261286 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0260681 |
| CDK19 | cyclin-dependent kinase 19 | 0.0258234 |
| AFDN | afadin, adherens junction formation factor | 0.0257442 |
| SET | SET nuclear proto-oncogene | 0.0254773 |
| TLN1 | talin 1 | 0.0253334 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0252066 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0252004 |
| NGLY1 | N-glycanase 1 | 0.0247941 |
| NOTCH2 | notch 2 | 0.0247506 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0246607 |
| FAM13A | family with sequence similarity 13, member A | 0.0240459 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0239484 |
| OPTN | optineurin | 0.0238012 |
| PCBP2 | poly(rC) binding protein 2 | 0.0235518 |
| RPL37 | ribosomal protein L37 | 0.023463 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0233147 |
| CDCP1 | CUB domain containing protein 1 | 0.0233038 |
| SMAD3 | SMAD family member 3 | 0.0230696 |
| TMF1 | TATA element modulatory factor 1 | 0.0230125 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0229828 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0228983 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.217642 |
| IER3 | immediate early response 3 | -0.149134 |
| GLIS3 | GLIS family zinc finger 3 | -0.126391 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.123272 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.116783 |
| EXT1 | exostosin glycosyltransferase 1 | -0.114182 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.111932 |
| HMGA2 | high mobility group AT-hook 2 | -0.10518 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.104201 |
| CDH13 | cadherin 13 | -0.0840381 |
| RPS24 | ribosomal protein S24 | -0.0837796 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0706611 |
| BICC1 | BicC family RNA binding protein 1 | -0.0685805 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0682317 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0646218 |
| CANX | calnexin | -0.0614388 |
| TUBB | tubulin, beta class I | -0.0570642 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0567685 |
| FN1 | fibronectin 1 | -0.0562427 |
| PGK1 | phosphoglycerate kinase 1 | -0.0547704 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0535001 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0526867 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0472367 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0471358 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0465009 |
| AHNAK | AHNAK nucleoprotein | -0.0459606 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0448433 |
| CTSD | cathepsin D | -0.0447777 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0447757 |
| VCL | vinculin | -0.0445222 |
| SMYD3 | SET and MYND domain containing 3 | -0.0426245 |
| QKI | QKI, KH domain containing, RNA binding | -0.0409338 |
| INTS6 | integrator complex subunit 6 | -0.0408863 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0401552 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.03996 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0397153 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0396877 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0394942 |
| ACTG1 | actin gamma 1 | -0.0393001 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0385955 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0381792 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.038095 |
| TMEM123 | transmembrane protein 123 | -0.037923 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0370505 |
| THBS1 | thrombospondin 1 | -0.0366015 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0365823 |
| HMGA1 | high mobility group AT-hook 1 | -0.0358551 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0350787 |
| TKT | transketolase | -0.0347927 |
| ERBIN | erbb2 interacting protein | -0.0346677 |
| GNAS | GNAS complex locus | -0.0346607 |
| CALR | calreticulin | -0.0342476 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0335085 |
| NF1 | neurofibromin 1 | -0.0333727 |
| OGA | O-GlcNAcase | -0.0329594 |
| MED13 | mediator complex subunit 13 | -0.0325077 |
| RPL36A | ribosomal protein L36a | -0.032183 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0319769 |
| RBM39 | RNA binding motif protein 39 | -0.0317115 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.031495 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0311465 |
| RHEB | Ras homolog enriched in brain | -0.0310254 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0309976 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0308306 |
| FRMD4A | FERM domain containing 4A | -0.0303552 |
| TMSB10 | thymosin beta 10 | -0.0303042 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0301208 |
| ZNF207 | zinc finger protein 207 | -0.0300502 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0299303 |
| FMR1 | fragile X mental retardation 1 | -0.0292791 |
| MED13L | mediator complex subunit 13-like | -0.0292545 |
| NABP1 | nucleic acid binding protein 1 | -0.0285204 |
| CUX1 | cut-like homeobox 1 | -0.0284428 |
| THBS2 | thrombospondin 2 | -0.0281646 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0280643 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0276544 |
| VCAN | versican | -0.0275668 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0271681 |
| AK1 | adenylate kinase 1 | -0.027158 |
| PARD3 | par-3 family cell polarity regulator | -0.0270952 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0263974 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.026329 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0261319 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0257689 |
| SEPTIN7 | septin 7 | -0.0257444 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.0256352 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.025586 |
| AUTS2 | autism susceptibility candidate 2 | -0.025541 |
| PRKCA | protein kinase C, alpha | -0.0251287 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | -0.0248293 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0248195 |
| PRR16 | proline rich 16 | -0.0247831 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0247797 |
| RPLP1 | ribosomal protein, large, P1 | -0.0246586 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0245255 |
| FBXO11 | F-box protein 11 | -0.0245064 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0244654 |
| SVIL | supervillin | -0.0244558 |
| BPTF | bromodomain PHD finger transcription factor | -0.0242446 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0241804 |