| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clofarabine perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clofarabine_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.115058 |
| PTMA | prothymosin, alpha | 0.099377 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0756379 |
| RPS6 | ribosomal protein S6 | 0.0660811 |
| LMO7 | LIM domain 7 | 0.0534507 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0495544 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0493744 |
| RBM15 | RNA binding motif protein 15 | 0.0473652 |
| RPS3 | ribosomal protein S3 | 0.0471652 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0449666 |
| RPS8 | ribosomal protein S8 | 0.0429147 |
| RPL35A | ribosomal protein L35a | 0.0427151 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0426712 |
| RPL23 | ribosomal protein L23 | 0.0425577 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0409797 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0386882 |
| TAPBP | TAP binding protein (tapasin) | 0.0377253 |
| GOLGB1 | golgin B1 | 0.0376429 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0374156 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0365151 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0358598 |
| NAV1 | neuron navigator 1 | 0.0357851 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0352045 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0348412 |
| GDNF | glial cell derived neurotrophic factor | 0.0344327 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0343484 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0336423 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.033149 |
| B2M | beta-2-microglobulin | 0.0330574 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0328046 |
| RNF145 | ring finger protein 145 | 0.0324302 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0321147 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0318739 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0310372 |
| RPLP2 | ribosomal protein, large, P2 | 0.0309111 |
| DSCAM | Down syndrome cell adhesion molecule | 0.030747 |
| RPL9 | ribosomal protein L9 | 0.0306579 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0305827 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0302476 |
| PCBP2 | poly(rC) binding protein 2 | 0.0301519 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0294871 |
| RPS16 | ribosomal protein S16 | 0.0292527 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0292393 |
| TPM3 | tropomyosin 3 | 0.0290465 |
| CBX3 | chromobox homolog 3 | 0.0287708 |
| RPL15 | ribosomal protein L15 | 0.0287133 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0286939 |
| SET | SET nuclear proto-oncogene | 0.0284924 |
| ZNF451 | zinc finger protein 451 | 0.0281029 |
| TPI1 | triosephosphate isomerase 1 | 0.0278933 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0278057 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0277471 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0277442 |
| FAM120A | family with sequence similarity 120A | 0.0277169 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0277127 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0274343 |
| ADAR | adenosine deaminase, RNA-specific | 0.0273259 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.0273216 |
| NCKAP1 | NCK-associated protein 1 | 0.0272662 |
| POM121C | POM121 transmembrane nucleoporin C | 0.0272287 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0266669 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0266316 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.026556 |
| PNN | pinin, desmosome associated protein | 0.0262758 |
| ARRDC3 | arrestin domain containing 3 | 0.0260501 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0257866 |
| WWOX | WW domain containing oxidoreductase | 0.0257641 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.025677 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0256757 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0255274 |
| EFHD2 | EF-hand domain family, member D2 | 0.0253503 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0251784 |
| ATP11A | ATPase, class VI, type 11A | 0.0251154 |
| INTS6 | integrator complex subunit 6 | 0.0250787 |
| PKM | pyruvate kinase, muscle | 0.025055 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0250298 |
| SETD2 | SET domain containing 2 | 0.0248374 |
| JUN | jun proto-oncogene | 0.0248307 |
| RPL26 | ribosomal protein L26 | 0.0247338 |
| CMIP | c-Maf inducing protein | 0.0246376 |
| PHIP | pleckstrin homology domain interacting protein | 0.0246345 |
| TNS3 | tensin 3 | 0.0243656 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0242372 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0242109 |
| USPL1 | ubiquitin specific peptidase like 1 | 0.0241255 |
| RPL37A | ribosomal protein L37a | 0.0240574 |
| WDR45B | WD repeat domain 45B | 0.023935 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0238943 |
| ZNF395 | zinc finger protein 395 | 0.0238543 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0238517 |
| RPS12 | ribosomal protein S12 | 0.0238245 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0237924 |
| PTGES2 | prostaglandin E synthase 2 | 0.0236979 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0236793 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.0235629 |
| DUSP6 | dual specificity phosphatase 6 | 0.0234257 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0234165 |
| RPS19 | ribosomal protein S19 | 0.0233834 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0233176 |
| ITM2C | integral membrane protein 2C | 0.0230802 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.249193 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.191856 |
| COL6A3 | collagen, type VI, alpha 3 | -0.183002 |
| COL1A2 | collagen, type I, alpha 2 | -0.121557 |
| CALU | calumenin | -0.119829 |
| LOX | lysyl oxidase | -0.104786 |
| HLA-B | major histocompatibility complex, class I, B | -0.0865467 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0864109 |
| COL1A1 | collagen, type I, alpha 1 | -0.0856762 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0790776 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0680681 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.065929 |
| CALR | calreticulin | -0.0648549 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0628123 |
| EGFR | epidermal growth factor receptor | -0.0621673 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0618924 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0598398 |
| AUTS2 | autism susceptibility candidate 2 | -0.0586376 |
| VCL | vinculin | -0.0575451 |
| UBC | ubiquitin C | -0.0568911 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0543752 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0535047 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0526718 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0524128 |
| NRXN3 | neurexin 3 | -0.0513889 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0512552 |
| LOXL2 | lysyl oxidase-like 2 | -0.0507354 |
| ATP13A3 | ATPase type 13A3 | -0.048761 |
| SEC24D | SEC24 family member D | -0.0479166 |
| HLA-C | major histocompatibility complex, class I, C | -0.0473796 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0460645 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0454675 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0450293 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0449354 |
| CALD1 | caldesmon 1 | -0.0443782 |
| GLIS3 | GLIS family zinc finger 3 | -0.0443397 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0438654 |
| TPM4 | tropomyosin 4 | -0.0432814 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0421198 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0416405 |
| KAZN | kazrin, periplakin interacting protein | -0.0389708 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0387544 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0386723 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0384 |
| SMYD3 | SET and MYND domain containing 3 | -0.0376929 |
| HIP1 | huntingtin interacting protein 1 | -0.0376211 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0373421 |
| PHKB | phosphorylase kinase, beta | -0.0372351 |
| NF1 | neurofibromin 1 | -0.0369443 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0368184 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0364894 |
| HDLBP | high density lipoprotein binding protein | -0.0362412 |
| TUBB | tubulin, beta class I | -0.0361326 |
| CLIC4 | chloride intracellular channel 4 | -0.0359531 |
| LAMA4 | laminin, alpha 4 | -0.0354909 |
| TLK1 | tousled-like kinase 1 | -0.0354215 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0353994 |
| AHR | aryl hydrocarbon receptor | -0.0352822 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0351467 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0350145 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0347307 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0347193 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0347118 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.034419 |
| CANX | calnexin | -0.0343725 |
| HPCAL1 | hippocalcin-like 1 | -0.0342739 |
| RASAL2 | RAS protein activator like 2 | -0.0341334 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0340724 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0339093 |
| HMGA2 | high mobility group AT-hook 2 | -0.0338034 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0330552 |
| CDK6 | cyclin-dependent kinase 6 | -0.0329218 |
| TRRAP | transformation/transcription domain-associated protein | -0.0327952 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.03238 |
| PRELID2 | PRELI domain containing 2 | -0.0321611 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0321316 |
| TMEM165 | transmembrane protein 165 | -0.0319557 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0318499 |
| RTN4 | reticulon 4 | -0.0314637 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0312679 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0312408 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0311123 |
| AK1 | adenylate kinase 1 | -0.0309251 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0307298 |
| AHNAK | AHNAK nucleoprotein | -0.0307231 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0307141 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0306172 |
| DYM | dymeclin | -0.030252 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0302402 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0302209 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0300486 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0300061 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0299857 |
| SEPTIN7 | septin 7 | -0.02988 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0298762 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0298563 |
| COL5A2 | collagen, type V, alpha 2 | -0.0297393 |
| GOLGA4 | golgin A4 | -0.0295043 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0286239 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0284602 |
