| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clofarabine perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clofarabine_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.102281 |
| GOLGA4 | golgin A4 | 0.0895402 |
| RBM39 | RNA binding motif protein 39 | 0.0819098 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.080044 |
| RPS3 | ribosomal protein S3 | 0.0749496 |
| RPS12 | ribosomal protein S12 | 0.0729538 |
| LDHA | lactate dehydrogenase A | 0.0704223 |
| PTMA | prothymosin, alpha | 0.069218 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0683475 |
| SET | SET nuclear proto-oncogene | 0.065819 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0629162 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0621066 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0565396 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0553073 |
| BRD4 | bromodomain containing 4 | 0.0549684 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.053369 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.053117 |
| ASPH | aspartate beta-hydroxylase | 0.0523335 |
| FN1 | fibronectin 1 | 0.0521415 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.051926 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.051462 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0485085 |
| RPL14 | ribosomal protein L14 | 0.0479747 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0477954 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0477775 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0475996 |
| RPS6 | ribosomal protein S6 | 0.0475596 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0469528 |
| RPL26 | ribosomal protein L26 | 0.0464589 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0450686 |
| SETD2 | SET domain containing 2 | 0.0446433 |
| RPL37 | ribosomal protein L37 | 0.0443845 |
| MSN | moesin | 0.0428233 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0427109 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0419265 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0417826 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0409916 |
| RRBP1 | ribosome binding protein 1 | 0.0403134 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0400482 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0396443 |
| RPL37A | ribosomal protein L37a | 0.0395583 |
| DYNC1I2 | dynein, cytoplasmic 1, intermediate chain 2 | 0.0389673 |
| HSPA8 | heat shock 70kDa protein 8 | 0.038582 |
| PNN | pinin, desmosome associated protein | 0.0382601 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0377023 |
| MORF4L2 | mortality factor 4 like 2 | 0.0376633 |
| RPL35A | ribosomal protein L35a | 0.0373503 |
| RDX | radixin | 0.0370439 |
| MT2A | metallothionein 2A | 0.0370222 |
| RPS27A | ribosomal protein S27a | 0.0369841 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0367941 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0359869 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.035042 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0347893 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.034562 |
| RBM25 | RNA binding motif protein 25 | 0.0345218 |
| GOLGB1 | golgin B1 | 0.0337108 |
| H3-3B | H3.3 histone B | 0.0335903 |
| APP | amyloid beta (A4) precursor protein | 0.033517 |
| TPI1 | triosephosphate isomerase 1 | 0.0335022 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0332555 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | 0.0332372 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0330905 |
| RAN | RAN, member RAS oncogene family | 0.0330779 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0324267 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0323026 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0322513 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | 0.032178 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0321609 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 0.0321327 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0319607 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0318815 |
| RPL15 | ribosomal protein L15 | 0.0317773 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0314558 |
| TMEM263 | transmembrane protein 263 | 0.0313235 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0312472 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0312379 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0311721 |
| RPS8 | ribosomal protein S8 | 0.0309714 |
| DNAJC25 | DnaJ (Hsp40) homolog, subfamily C , member 25 | 0.0307741 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0303396 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0302452 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0299451 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.029938 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.029858 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0292441 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0290539 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0290189 |
| USP8 | ubiquitin specific peptidase 8 | 0.0289431 |
| TAPBP | TAP binding protein (tapasin) | 0.0287589 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0286225 |
| KIF5B | kinesin family member 5B | 0.0285415 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0284417 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0281711 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0281451 |
| RAD51B | RAD51 paralog B | 0.0280173 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0280145 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0280102 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0279943 |
| YY1 | YY1 transcription factor | 0.0277912 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.392071 |
| PKM | pyruvate kinase, muscle | -0.0612852 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0497184 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0431692 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0431295 |
| BSG | basigin (Ok blood group) | -0.0431033 |
| TMEM123 | transmembrane protein 123 | -0.0387616 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0370379 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0353367 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0352474 |
| ZNF438 | zinc finger protein 438 | -0.0346711 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0344808 |
| PRR16 | proline rich 16 | -0.0342168 |
| FBXO11 | F-box protein 11 | -0.0341091 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0339301 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0330854 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0328263 |
| AHCTF1 | AT hook containing transcription factor 1 | -0.0327501 |
| USP34 | ubiquitin specific peptidase 34 | -0.0326306 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0325378 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0324969 |
| HELZ | helicase with zinc finger | -0.0321031 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0320664 |
| NUP98 | nucleoporin 98kDa | -0.0317156 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0316562 |
| ZNF609 | zinc finger protein 609 | -0.031243 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0311999 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0309504 |
| SQSTM1 | sequestosome 1 | -0.0308783 |
| MED13 | mediator complex subunit 13 | -0.0308421 |
| VIM | vimentin | -0.0304726 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0299937 |
| GNAS | GNAS complex locus | -0.0299678 |
| ERBIN | erbb2 interacting protein | -0.029459 |
| COG5 | component of oligomeric golgi complex 5 | -0.0293864 |
| COLEC11 | collectin sub-family member 11 | -0.0291375 |
| TUBA1B | tubulin, alpha 1b | -0.0289969 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | -0.0288989 |
| SLC36A4 | solute carrier family 36 (proton/amino acid symporter), member 4 | -0.0286402 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0285055 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | -0.0284923 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0284148 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0279646 |
| SMYD3 | SET and MYND domain containing 3 | -0.0275973 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0270234 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.026904 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | -0.0266756 |
| ANXA1 | annexin A1 | -0.0265304 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0264673 |
| TUBB | tubulin, beta class I | -0.0264421 |
| TUT4 | terminal uridylyl transferase 4 | -0.026432 |
| RPS14 | ribosomal protein S14 | -0.0261991 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.0261215 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0261034 |
| INTS6 | integrator complex subunit 6 | -0.0261022 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0260499 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.025465 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | -0.0254466 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0254119 |
| PERP | PERP, TP53 apoptosis effector | -0.025244 |
| ARPC3 | actin related protein 2/3 complex, subunit 3, 21kDa | -0.0251178 |
| RIGI | RNA sensor RIG-I | -0.0250986 |
| RASSF3 | Ras association (RalGDS/AF-6) domain family member 3 | -0.0249074 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0247451 |
| SRSF3 | serine/arginine-rich splicing factor 3 | -0.024636 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0244261 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 | -0.0244102 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0243811 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0242995 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | -0.0238289 |
| CPLANE1 | ciliogenesis and planar polarity effector complex subunit 1 | -0.0236692 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.023634 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0235774 |
| KDM6B | lysine (K)-specific demethylase 6B | -0.0234555 |
| ETFA | electron-transfer-flavoprotein, alpha polypeptide | -0.023211 |
| KLHL24 | kelch-like family member 24 | -0.0231901 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.02315 |
| LAMA5 | laminin, alpha 5 | -0.0230597 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.022986 |
| TMSB10 | thymosin beta 10 | -0.0229087 |
| HLA-C | major histocompatibility complex, class I, C | -0.0228998 |
| PRKCA | protein kinase C, alpha | -0.0228817 |
| TBK1 | TANK-binding kinase 1 | -0.0227727 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0227128 |
| PIK3CB | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta | -0.0226754 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0225536 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0224574 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0222204 |
| DIAPH3 | diaphanous-related formin 3 | -0.0222152 |
| ADIPOR2 | adiponectin receptor 2 | -0.0221538 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0221304 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0220998 |
| LARP4 | La ribonucleoprotein domain family, member 4 | -0.0220941 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0220799 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0220256 |
| FAM120B | family with sequence similarity 120B | -0.0220146 |
| RPLP0 | ribosomal protein, large, P0 | -0.0219782 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0219518 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0219171 |
| PHTF2 | putative homeodomain transcription factor 2 | -0.0218662 |