Clonazepam Gene Set

Dataset HMDB Metabolites of Enzymes
Category physical interactions
Type metabolite
Description 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation. (Chemical Entities of Biological Interest Ontology, CHEBI_3756)
External Link http://www.hmdb.ca/metabolites/HMDB15201
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Genes

20 interacting proteins for the Clonazepam metabolite from the curated HMDB Metabolites of Enzymes dataset.

Symbol Name
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GABRD gamma-aminobutyric acid (GABA) A receptor, delta
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GABRR3 gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene)
TSPO translocator protein (18kDa)