| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clonidine (hydrochloride)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.170147 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.166522 |
| DST | dystonin | 0.109025 |
| PRSS23 | protease, serine, 23 | 0.097052 |
| COL5A1 | collagen, type V, alpha 1 | 0.09703 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0957275 |
| AHNAK | AHNAK nucleoprotein | 0.0878547 |
| MSN | moesin | 0.0818253 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0767876 |
| PLEC | plectin | 0.0762273 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0754274 |
| MAP1B | microtubule-associated protein 1B | 0.0746505 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0741232 |
| VCL | vinculin | 0.0710244 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0707417 |
| DSPP | dentin sialophosphoprotein | 0.0699174 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0682238 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0674779 |
| ASPH | aspartate beta-hydroxylase | 0.0669519 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0669164 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0660647 |
| FSTL1 | follistatin-like 1 | 0.0657953 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0616371 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0614317 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0588778 |
| CALR | calreticulin | 0.0581605 |
| CDH13 | cadherin 13 | 0.0579547 |
| HDAC9 | histone deacetylase 9 | 0.0578511 |
| TPM3 | tropomyosin 3 | 0.0577414 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0563432 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0544874 |
| FLNA | filamin A, alpha | 0.0518065 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0513077 |
| MCL1 | myeloid cell leukemia 1 | 0.0511322 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0507222 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0500836 |
| RASAL2 | RAS protein activator like 2 | 0.0494285 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0488977 |
| TMSB4X | thymosin beta 4, X-linked | 0.0482201 |
| INTS6 | integrator complex subunit 6 | 0.0463673 |
| APP | amyloid beta (A4) precursor protein | 0.0454114 |
| PLAT | plasminogen activator, tissue | 0.045322 |
| CYTH3 | cytohesin 3 | 0.0448378 |
| PRELID2 | PRELI domain containing 2 | 0.0447812 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0442222 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0437411 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0431346 |
| CANX | calnexin | 0.0428412 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0427268 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0425142 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0424857 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0415035 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0408769 |
| GLIS3 | GLIS family zinc finger 3 | 0.0406096 |
| CENPF | centromere protein F, 350/400kDa | 0.0390764 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0389933 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0386888 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0383496 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0382553 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0370415 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0369984 |
| B2M | beta-2-microglobulin | 0.0369663 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0365931 |
| VEGFC | vascular endothelial growth factor C | 0.0364651 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0359967 |
| TLE4 | transducin-like enhancer of split 4 | 0.0355677 |
| GOLGB1 | golgin B1 | 0.0347053 |
| RIGI | RNA sensor RIG-I | 0.0339794 |
| ANXA1 | annexin A1 | 0.0337529 |
| SP100 | SP100 nuclear antigen | 0.0336137 |
| EGFR | epidermal growth factor receptor | 0.0329238 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0327627 |
| NEK7 | NIMA-related kinase 7 | 0.0323893 |
| LMNA | lamin A/C | 0.0321756 |
| SON | SON DNA binding protein | 0.03204 |
| EFNA5 | ephrin-A5 | 0.0318699 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.031717 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0314503 |
| JAZF1 | JAZF zinc finger 1 | 0.0314444 |
| ERBIN | erbb2 interacting protein | 0.0312275 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0310296 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0309665 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0308613 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0305927 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.030505 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0304914 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0303218 |
| NIBAN1 | niban apoptosis regulator 1 | 0.0302508 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0295413 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0292861 |
| DLGAP3 | discs, large (Drosophila) homolog-associated protein 3 | 0.0289746 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0287912 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.028725 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0279237 |
| RNF213 | ring finger protein 213 | 0.027905 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0278936 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0278216 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0277028 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0275526 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0275415 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.219134 |
| VIM | vimentin | -0.188632 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.184317 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.129132 |
| NDRG1 | N-myc downstream regulated 1 | -0.107281 |
| PODXL | podocalyxin-like | -0.106879 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0962103 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0830735 |
| LOXL2 | lysyl oxidase-like 2 | -0.0755366 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0690361 |
| ANXA2 | annexin A2 | -0.065575 |
| LOX | lysyl oxidase | -0.063337 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0602134 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0598525 |
| THBS2 | thrombospondin 2 | -0.0586138 |
| CD99 | CD99 molecule | -0.0538157 |
| S100A10 | S100 calcium binding protein A10 | -0.0521929 |
| COL1A2 | collagen, type I, alpha 2 | -0.051387 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0506922 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0504323 |
| UBC | ubiquitin C | -0.0498183 |
| S100A6 | S100 calcium binding protein A6 | -0.0467989 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0449811 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.04392 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0428427 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0418054 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0412356 |
| ZNF292 | zinc finger protein 292 | -0.0406141 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0399888 |
| RTN4 | reticulon 4 | -0.039899 |
| CSTB | cystatin B (stefin B) | -0.0398909 |
| HLA-B | major histocompatibility complex, class I, B | -0.0394816 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0380745 |
| FBN1 | fibrillin 1 | -0.0375978 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.0369403 |
| SBF2 | SET binding factor 2 | -0.0368559 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0363651 |
| MYADM | myeloid-associated differentiation marker | -0.0360187 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0348957 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0340254 |
| TAPBP | TAP binding protein (tapasin) | -0.0336935 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0336923 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0323744 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0319316 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0307277 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0302636 |
| HLA-C | major histocompatibility complex, class I, C | -0.0298085 |
| FLNB | filamin B, beta | -0.0292394 |
| SP3 | Sp3 transcription factor | -0.0289423 |
| RNF24 | ring finger protein 24 | -0.0285351 |
| BSG | basigin (Ok blood group) | -0.0281921 |
| RAI1 | retinoic acid induced 1 | -0.0280774 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0278016 |
| MX2 | MX dynamin-like GTPase 2 | -0.027662 |
| COL3A1 | collagen, type III, alpha 1 | -0.0276289 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0267809 |
| RPS24 | ribosomal protein S24 | -0.0264198 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0257064 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0255236 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0253601 |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme | -0.0252267 |
| PXDN | peroxidasin | -0.0251178 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0250018 |
| RPS6 | ribosomal protein S6 | -0.0241388 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0236326 |
| HLA-E | major histocompatibility complex, class I, E | -0.0233186 |
| POTEF | POTE ankyrin domain family, member F | -0.0231903 |
| PRKD3 | protein kinase D3 | -0.023115 |
| WDFY1 | WD repeat and FYVE domain containing 1 | -0.0227576 |
| RLF | rearranged L-myc fusion | -0.0227014 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0226247 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0225769 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0224879 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0223946 |
| CCND1 | cyclin D1 | -0.0223478 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0221759 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0220862 |
| H3-3B | H3.3 histone B | -0.0220177 |
| SUCNR1 | succinate receptor 1 | -0.0220152 |
| FTL | ferritin, light polypeptide | -0.0218426 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0216072 |
| ZFR | zinc finger RNA binding protein | -0.0214469 |
| KLHL24 | kelch-like family member 24 | -0.0213701 |
| GNAS | GNAS complex locus | -0.0209337 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0207775 |
| MTSS1 | metastasis suppressor 1 | -0.0206957 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0206785 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.020329 |
| DEPP1 | DEPP autophagy regulator 1 | -0.0202469 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0198836 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0198506 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0196989 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0195245 |
| LDHA | lactate dehydrogenase A | -0.019515 |
| RPL28 | ribosomal protein L28 | -0.0194059 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0193908 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0193749 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0192722 |
| MT2A | metallothionein 2A | -0.0192499 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0192213 |
