| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clonidine (hydrochloride)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.134699 |
| YAP1 | Yes-associated protein 1 | 0.0909193 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0862309 |
| HMGA2 | high mobility group AT-hook 2 | 0.0834593 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0803477 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0783208 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0650218 |
| INTS6 | integrator complex subunit 6 | 0.0628499 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0588835 |
| PDGFC | platelet derived growth factor C | 0.0568311 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0533356 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0532555 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0493948 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0478782 |
| YBX3 | Y box binding protein 3 | 0.0467779 |
| DENND5A | DENN/MADD domain containing 5A | 0.0465772 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0442439 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0442393 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0442072 |
| TPI1 | triosephosphate isomerase 1 | 0.0437822 |
| DST | dystonin | 0.0412481 |
| JMJD1C | jumonji domain containing 1C | 0.0406094 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0405381 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0403533 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0401229 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0394454 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0383081 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0378719 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0365241 |
| ADIPOR2 | adiponectin receptor 2 | 0.035894 |
| RTN4 | reticulon 4 | 0.0354903 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0349601 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0347504 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.034612 |
| RPL3 | ribosomal protein L3 | 0.0333992 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0331575 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.032885 |
| RPL23 | ribosomal protein L23 | 0.0324715 |
| RRM2 | ribonucleotide reductase M2 | 0.0324208 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0311325 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0309232 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0307741 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0302196 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0293147 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0292914 |
| RCOR1 | REST corepressor 1 | 0.0292336 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0281874 |
| CMIP | c-Maf inducing protein | 0.0281611 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0280259 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0279226 |
| TPM3 | tropomyosin 3 | 0.0277327 |
| ZNF638 | zinc finger protein 638 | 0.0277124 |
| MPG | N-methylpurine-DNA glycosylase | 0.0274743 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.027403 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0271265 |
| CTBP2 | C-terminal binding protein 2 | 0.0270996 |
| EZR | ezrin | 0.0269737 |
| HDAC4 | histone deacetylase 4 | 0.026816 |
| RPS2 | ribosomal protein S2 | 0.0267759 |
| WWOX | WW domain containing oxidoreductase | 0.0265528 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0263162 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0262632 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 | 0.0262151 |
| BRD2 | bromodomain containing 2 | 0.0261797 |
| PRKCE | protein kinase C, epsilon | 0.0261711 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0261253 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0259625 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0255559 |
| PLEC | plectin | 0.0253562 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0253178 |
| ZNF217 | zinc finger protein 217 | 0.0252424 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0252301 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0251967 |
| CEP192 | centrosomal protein 192kDa | 0.0249285 |
| SKI | SKI proto-oncogene | 0.0247144 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0246256 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.0245683 |
| PCDH7 | protocadherin 7 | 0.024332 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0242418 |
| RPS12 | ribosomal protein S12 | 0.0240509 |
| NEBL | nebulette | 0.0238268 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0235915 |
| PCM1 | pericentriolar material 1 | 0.0235826 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0235748 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0231384 |
| CEP250 | centrosomal protein 250kDa | 0.0230697 |
| MCL1 | myeloid cell leukemia 1 | 0.0229901 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0227044 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0225196 |
| DIAPH1 | diaphanous-related formin 1 | 0.0224344 |
| NFIB | nuclear factor I/B | 0.0223525 |
| CLPTM1L | CLPTM1-like | 0.0223198 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0221033 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0220641 |
| ATP11A | ATPase, class VI, type 11A | 0.0219963 |
| ALMS1 | Alstrom syndrome protein 1 | 0.0219898 |
| ERBIN | erbb2 interacting protein | 0.0218649 |
| ETV6 | ets variant 6 | 0.0217278 |
| TSPAN9 | tetraspanin 9 | 0.0217236 |
| PDCD6 | programmed cell death 6 | 0.0216908 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.315641 |
| VIM | vimentin | -0.216257 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.088533 |
| NLGN1 | neuroligin 1 | -0.073745 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.07281 |
| HMGA1 | high mobility group AT-hook 1 | -0.0718904 |
| BCHE | butyrylcholinesterase | -0.0715952 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0712567 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0662351 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0643767 |
| MMP12 | matrix metallopeptidase 12 | -0.0572246 |
| TMEM123 | transmembrane protein 123 | -0.0553637 |
| SYT1 | synaptotagmin I | -0.0529054 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0529013 |
| EHBP1 | EH domain binding protein 1 | -0.0520912 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0499895 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0476552 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0474663 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0471999 |
| MGAT4C | MGAT4 family, member C | -0.0468269 |
| POTEF | POTE ankyrin domain family, member F | -0.0466086 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0462517 |
| CLDN1 | claudin 1 | -0.0460326 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0452932 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0432737 |
| EGR1 | early growth response 1 | -0.0431773 |
| RASAL2 | RAS protein activator like 2 | -0.0419481 |
| KIF5B | kinesin family member 5B | -0.0414969 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0405674 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0403895 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0396081 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0388658 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0385834 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0385542 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0382738 |
| LDHA | lactate dehydrogenase A | -0.0381832 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0376607 |
| TUBA1B | tubulin, alpha 1b | -0.0376345 |
| USP34 | ubiquitin specific peptidase 34 | -0.0376175 |
| ACTG1 | actin gamma 1 | -0.0368095 |
| MKI67 | marker of proliferation Ki-67 | -0.0360712 |
| NAV3 | neuron navigator 3 | -0.0360513 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.035611 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.035364 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0345997 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0342223 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0333328 |
| LDHB | lactate dehydrogenase B | -0.0331172 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0320025 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0314597 |
| TUBB | tubulin, beta class I | -0.030762 |
| RHOA | ras homolog family member A | -0.0306752 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0305337 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0302075 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0299356 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0297753 |
| TPM4 | tropomyosin 4 | -0.0293566 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0291716 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0287009 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0280775 |
| TMEM41B | transmembrane protein 41B | -0.0277603 |
| CCN2 | cellular communication network factor 2 | -0.0275063 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0272547 |
| ENO1 | enolase 1, (alpha) | -0.026971 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0268403 |
| ZNF804A | zinc finger protein 804A | -0.0262 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0260898 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0258447 |
| WDR45B | WD repeat domain 45B | -0.0256279 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0255408 |
| PRR11 | proline rich 11 | -0.0255356 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0255201 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0249749 |
| TENM3 | teneurin transmembrane protein 3 | -0.0249406 |
| HLA-A | major histocompatibility complex, class I, A | -0.0248842 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0246432 |
| ANXA2 | annexin A2 | -0.0244418 |
| AREG | amphiregulin | -0.0243502 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0242535 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0240473 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.023733 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.023529 |
| KIF18B | kinesin family member 18B | -0.0233118 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0232524 |
| MAP4 | microtubule-associated protein 4 | -0.0232485 |
| VMP1 | vacuole membrane protein 1 | -0.0231704 |
| FSTL5 | follistatin-like 5 | -0.0228095 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.0228013 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0227076 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0226117 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0224999 |
| LMO7 | LIM domain 7 | -0.0223754 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0221744 |
| ZNF292 | zinc finger protein 292 | -0.0221412 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0220221 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0219929 |
| RPS6 | ribosomal protein S6 | -0.0219503 |
| TXNRD1 | thioredoxin reductase 1 | -0.0218834 |
| S100A6 | S100 calcium binding protein A6 | -0.0217847 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0217323 |
