| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clonidine (hydrochloride)_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.183014 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.129253 |
| NAV2 | neuron navigator 2 | 0.112354 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.111706 |
| PLEC | plectin | 0.0989552 |
| FRMD4A | FERM domain containing 4A | 0.0972178 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.097006 |
| RNF213 | ring finger protein 213 | 0.0900386 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0859909 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0843382 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0801984 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0678521 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0673398 |
| CTBP2 | C-terminal binding protein 2 | 0.0670223 |
| FMNL2 | formin-like 2 | 0.0653946 |
| INTS6 | integrator complex subunit 6 | 0.0598861 |
| FTL | ferritin, light polypeptide | 0.0589941 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.057866 |
| AHNAK | AHNAK nucleoprotein | 0.0539892 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0534891 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.053279 |
| APOL1 | apolipoprotein L, 1 | 0.0527143 |
| LMNA | lamin A/C | 0.051688 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0484132 |
| CALR | calreticulin | 0.0481487 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0460457 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0460226 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0453773 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0451917 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0450227 |
| SP100 | SP100 nuclear antigen | 0.04471 |
| KYNU | kynureninase | 0.0440994 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0439884 |
| PRKCA | protein kinase C, alpha | 0.0438944 |
| ASPH | aspartate beta-hydroxylase | 0.0434674 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0428638 |
| NDRG1 | N-myc downstream regulated 1 | 0.0427723 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.041917 |
| TLE4 | transducin-like enhancer of split 4 | 0.0411862 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0403745 |
| RIGI | RNA sensor RIG-I | 0.0401399 |
| MSN | moesin | 0.0398037 |
| COPA | coatomer protein complex, subunit alpha | 0.0393575 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0393482 |
| B2M | beta-2-microglobulin | 0.0393141 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0386862 |
| MCL1 | myeloid cell leukemia 1 | 0.038381 |
| JAK1 | Janus kinase 1 | 0.0376647 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0375897 |
| SEPTIN9 | septin 9 | 0.0363325 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.035817 |
| ADM | adrenomedullin | 0.03578 |
| APP | amyloid beta (A4) precursor protein | 0.0346187 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0345709 |
| GPC5 | glypican 5 | 0.0345617 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0344305 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0338384 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0335529 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.03352 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.033505 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0333886 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0327551 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0327239 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0326637 |
| UBAP2 | ubiquitin associated protein 2 | 0.0325565 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0325391 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0324247 |
| SMAD3 | SMAD family member 3 | 0.0321645 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | 0.0317093 |
| TLN1 | talin 1 | 0.0315463 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0315283 |
| LYST | lysosomal trafficking regulator | 0.0310204 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0302906 |
| TMSB10 | thymosin beta 10 | 0.0301471 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0299751 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 0.0299673 |
| CANX | calnexin | 0.0298256 |
| ATF3 | activating transcription factor 3 | 0.0294489 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0281969 |
| SFTPA2 | surfactant protein A2 | 0.0280615 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0280458 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0278256 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.027605 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0274453 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 | 0.0271936 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0270608 |
| LRRC59 | leucine rich repeat containing 59 | 0.0268224 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0264281 |
| SQSTM1 | sequestosome 1 | 0.0261649 |
| RPL3 | ribosomal protein L3 | 0.0261224 |
| SPAG9 | sperm associated antigen 9 | 0.0258763 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0257656 |
| NIBAN1 | niban apoptosis regulator 1 | 0.0256061 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0254744 |
| HDAC9 | histone deacetylase 9 | 0.0254547 |
| USP53 | ubiquitin specific peptidase 53 | 0.0252642 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0251549 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0251244 |
| OPTN | optineurin | 0.0250478 |
| ACTN1 | actinin, alpha 1 | 0.0249811 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.182792 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.137037 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0979595 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0953187 |
| GPC6 | glypican 6 | -0.0864101 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0854593 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0797303 |
| RTN4 | reticulon 4 | -0.0690456 |
| GLIS3 | GLIS family zinc finger 3 | -0.0664396 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0651791 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0607165 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0604744 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.059486 |
| TGFB2 | transforming growth factor, beta 2 | -0.0561974 |
| RAI14 | retinoic acid induced 14 | -0.0549851 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0537413 |
| SP3 | Sp3 transcription factor | -0.0522146 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0501936 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0491912 |
| POTEF | POTE ankyrin domain family, member F | -0.047678 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.0466731 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.0458737 |
| TXNRD1 | thioredoxin reductase 1 | -0.0458588 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0435478 |
| TMEM165 | transmembrane protein 165 | -0.0433369 |
| ETV6 | ets variant 6 | -0.0430689 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0427336 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0415726 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0407005 |
| NRP1 | neuropilin 1 | -0.0406713 |
| CDCP1 | CUB domain containing protein 1 | -0.0399429 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0383736 |
| CSF1 | colony stimulating factor 1 (macrophage) | -0.0381321 |
| WDR43 | WD repeat domain 43 | -0.0379057 |
| GOLGA4 | golgin A4 | -0.0377601 |
| STK17A | serine/threonine kinase 17a | -0.0377271 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0376485 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0375744 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0372065 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0369311 |
| PTGR1 | prostaglandin reductase 1 | -0.0367124 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 | -0.0360895 |
| MAP1B | microtubule-associated protein 1B | -0.0357204 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0354087 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0339868 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0329252 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.032793 |
| CD44 | CD44 molecule (Indian blood group) | -0.0320898 |
| OSMR | oncostatin M receptor | -0.0318564 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0316627 |
| ATXN10 | ataxin 10 | -0.0313317 |
| TPM1 | tropomyosin 1 (alpha) | -0.0307102 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | -0.0302838 |
| GDA | guanine deaminase | -0.0300285 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0300239 |
| NRP2 | neuropilin 2 | -0.0299719 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0298157 |
| MFF | mitochondrial fission factor | -0.0295606 |
| SCFD2 | sec1 family domain containing 2 | -0.0291139 |
| SBF2 | SET binding factor 2 | -0.0286066 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0283126 |
| CBX3 | chromobox homolog 3 | -0.028054 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.028041 |
| OXR1 | oxidation resistance 1 | -0.0276582 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0275695 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0271429 |
| ANXA4 | annexin A4 | -0.0271162 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0270125 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0268686 |
| CLINT1 | clathrin interactor 1 | -0.0266753 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0265021 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | -0.0258287 |
| CP | ceruloplasmin (ferroxidase) | -0.0257883 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0257829 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0254252 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | -0.0253965 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0251999 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0245154 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | -0.0243451 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 | -0.0241221 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | -0.0241146 |
| CCDC146 | coiled-coil domain containing 146 | -0.024082 |
| ZNF652 | zinc finger protein 652 | -0.0240725 |
| TSPAN13 | tetraspanin 13 | -0.0239929 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0237999 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0237645 |
| BICC1 | BicC family RNA binding protein 1 | -0.0235374 |
| LDHA | lactate dehydrogenase A | -0.0234532 |
| VCAN | versican | -0.023413 |
| NOP58 | NOP58 ribonucleoprotein | -0.0232742 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0232204 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0229231 |
| SRPK2 | SRSF protein kinase 2 | -0.0228242 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0227643 |
| RIC1 | RAB6A GEF complex partner 1 | -0.0225697 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0223801 |
| TNS3 | tensin 3 | -0.0223101 |
| TRAM1 | translocation associated membrane protein 1 | -0.0220078 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0219559 |
| RAD54B | RAD54 homolog B (S. cerevisiae) | -0.0218016 |
