| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clonidine (hydrochloride)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.151797 |
| PLEC | plectin | 0.0984814 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0966135 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0748893 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0746975 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0692445 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.067299 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0649226 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0646533 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0643771 |
| ASPH | aspartate beta-hydroxylase | 0.062391 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0586262 |
| FMNL2 | formin-like 2 | 0.0583346 |
| MCL1 | myeloid cell leukemia 1 | 0.0582051 |
| EGFR | epidermal growth factor receptor | 0.0555897 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0536679 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0508275 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0495517 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0494447 |
| MSN | moesin | 0.0492714 |
| FAM107B | family with sequence similarity 107, member B | 0.0474427 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.046344 |
| AHNAK | AHNAK nucleoprotein | 0.0463262 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0463187 |
| LMO7 | LIM domain 7 | 0.0455136 |
| INTS6 | integrator complex subunit 6 | 0.0438842 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0427003 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0426095 |
| HMGA2 | high mobility group AT-hook 2 | 0.0420784 |
| FLNA | filamin A, alpha | 0.039717 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.038912 |
| FRMD6 | FERM domain containing 6 | 0.0387517 |
| ST6GAL2 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 | 0.0387419 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0386029 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0384596 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0375764 |
| FLNB | filamin B, beta | 0.0374624 |
| ACTN4 | actinin, alpha 4 | 0.0365668 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0362191 |
| SMAD3 | SMAD family member 3 | 0.036144 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0359456 |
| DSCAM | Down syndrome cell adhesion molecule | 0.035879 |
| RND3 | Rho family GTPase 3 | 0.0355665 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0351883 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0351577 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0351333 |
| PRKCA | protein kinase C, alpha | 0.0350773 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0342608 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.034213 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0341372 |
| GOLGB1 | golgin B1 | 0.0340681 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0338562 |
| MYO10 | myosin X | 0.0326768 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.03266 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0326463 |
| USP53 | ubiquitin specific peptidase 53 | 0.0324768 |
| CTBP2 | C-terminal binding protein 2 | 0.0319368 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0318055 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0314034 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0313142 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0312465 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0303737 |
| GOLGA3 | golgin A3 | 0.0301123 |
| AADAC | arylacetamide deacetylase | 0.0297827 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0297467 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0296604 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0293396 |
| MED13 | mediator complex subunit 13 | 0.0290575 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0289332 |
| MYOF | myoferlin | 0.0286897 |
| ACTN1 | actinin, alpha 1 | 0.028677 |
| EZR | ezrin | 0.0286496 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0285918 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0284056 |
| GPATCH2L | G patch domain containing 2-like | 0.0283971 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0283683 |
| DST | dystonin | 0.0283292 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0282913 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0282858 |
| SMYD3 | SET and MYND domain containing 3 | 0.0282826 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0282772 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0281107 |
| VCL | vinculin | 0.0278182 |
| RASAL2 | RAS protein activator like 2 | 0.0275667 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0275417 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 0.0271046 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0265663 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.0264635 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | 0.0260242 |
| NABP1 | nucleic acid binding protein 1 | 0.0259951 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0257807 |
| ZNF638 | zinc finger protein 638 | 0.0256815 |
| TNS1 | tensin 1 | 0.0254611 |
| SEPTIN9 | septin 9 | 0.0251543 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0250114 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0249704 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0247982 |
| BRD2 | bromodomain containing 2 | 0.0247926 |
| EFNA5 | ephrin-A5 | 0.0247205 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0243244 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.274947 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.229293 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.210594 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.154562 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.131303 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.100832 |
| FTL | ferritin, light polypeptide | -0.100618 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0966181 |
| CA12 | carbonic anhydrase XII | -0.080777 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0738864 |
| NDRG1 | N-myc downstream regulated 1 | -0.0689396 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0686823 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0646538 |
| OSMR | oncostatin M receptor | -0.064549 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0592401 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0587451 |
| POTEF | POTE ankyrin domain family, member F | -0.0586452 |
| LDHA | lactate dehydrogenase A | -0.058549 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0569184 |
| VIM | vimentin | -0.0545184 |
| MT2A | metallothionein 2A | -0.0528857 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0491174 |
| HMGA1 | high mobility group AT-hook 1 | -0.0490294 |
| USP3 | ubiquitin specific peptidase 3 | -0.0470096 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0454413 |
| RIN2 | Ras and Rab interactor 2 | -0.0450317 |
| TMSB10 | thymosin beta 10 | -0.0442997 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0442387 |
| KRT81 | keratin 81, type II | -0.0440143 |
| RPS16 | ribosomal protein S16 | -0.0438249 |
| PDE10A | phosphodiesterase 10A | -0.0435485 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0432753 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0424112 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0412074 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0410124 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0405528 |
| RPS6 | ribosomal protein S6 | -0.0402849 |
| RPLP1 | ribosomal protein, large, P1 | -0.0402796 |
| GPRIN3 | GPRIN family member 3 | -0.0395635 |
| UBC | ubiquitin C | -0.0391015 |
| TXNRD1 | thioredoxin reductase 1 | -0.0383574 |
| PFN1 | profilin 1 | -0.0380698 |
| ACTG1 | actin gamma 1 | -0.0378884 |
| ZNF292 | zinc finger protein 292 | -0.0373033 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0359867 |
| AXL | AXL receptor tyrosine kinase | -0.035723 |
| NRP1 | neuropilin 1 | -0.0348696 |
| TBK1 | TANK-binding kinase 1 | -0.0347021 |
| RPS24 | ribosomal protein S24 | -0.0344459 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0343925 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0340287 |
| S100A6 | S100 calcium binding protein A6 | -0.0331913 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0331081 |
| FA2H | fatty acid 2-hydroxylase | -0.0329932 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0324711 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0319161 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0313595 |
| MT1X | metallothionein 1X | -0.0306789 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0305302 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0305241 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0303994 |
| RTN4 | reticulon 4 | -0.029927 |
| TGM2 | transglutaminase 2 | -0.029529 |
| PGK1 | phosphoglycerate kinase 1 | -0.0291575 |
| TKT | transketolase | -0.0287478 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0287464 |
| TMEM165 | transmembrane protein 165 | -0.0287178 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.028656 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0280949 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0279607 |
| LDHB | lactate dehydrogenase B | -0.0279167 |
| CD68 | CD68 molecule | -0.0274326 |
| KRT7 | keratin 7, type II | -0.0274042 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0273372 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.026951 |
| PLSCR1 | phospholipid scramblase 1 | -0.025969 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0259658 |
| CMIP | c-Maf inducing protein | -0.0258068 |
| RNF24 | ring finger protein 24 | -0.0257881 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0256096 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0254405 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0254259 |
| RPL35A | ribosomal protein L35a | -0.0253087 |
| DENND4C | DENN/MADD domain containing 4C | -0.0252935 |
| AOPEP | aminopeptidase O (putative) | -0.0252225 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0248445 |
| MYADM | myeloid-associated differentiation marker | -0.0246678 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0246167 |
| RPL12 | ribosomal protein L12 | -0.0244259 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0244237 |
| RPLP0 | ribosomal protein, large, P0 | -0.02439 |
| STC1 | stanniocalcin 1 | -0.024271 |
| TAPBP | TAP binding protein (tapasin) | -0.0239788 |
| MAP1B | microtubule-associated protein 1B | -0.0238116 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0236935 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0236642 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0235334 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0233205 |
| RPS13 | ribosomal protein S13 | -0.0233051 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0231813 |
