| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clonidine (hydrochloride)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLEC | plectin | 0.086629 |
| FLNB | filamin B, beta | 0.0732494 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0632343 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0629479 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0539442 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0455846 |
| ITGA6 | integrin, alpha 6 | 0.0416441 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0399179 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0366181 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0349819 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0347159 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.033828 |
| AHNAK | AHNAK nucleoprotein | 0.0334136 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0333583 |
| DSPP | dentin sialophosphoprotein | 0.0319053 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0317767 |
| EFNA5 | ephrin-A5 | 0.0301347 |
| SMAD3 | SMAD family member 3 | 0.0297569 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0290355 |
| VCL | vinculin | 0.0282533 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0281252 |
| MSN | moesin | 0.0280389 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.02725 |
| PDLIM5 | PDZ and LIM domain 5 | 0.027121 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0268542 |
| SEPTIN9 | septin 9 | 0.0260865 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0255689 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0252936 |
| INTS6 | integrator complex subunit 6 | 0.0252079 |
| BCL2L1 | BCL2-like 1 | 0.0249262 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0248119 |
| TMEM164 | transmembrane protein 164 | 0.0247012 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0246228 |
| LAMA4 | laminin, alpha 4 | 0.0246075 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0245097 |
| ACTN4 | actinin, alpha 4 | 0.0233488 |
| CORO1C | coronin, actin binding protein, 1C | 0.0225339 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0222655 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0221842 |
| AFDN | afadin, adherens junction formation factor | 0.0221596 |
| HMGA2 | high mobility group AT-hook 2 | 0.0221295 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0220004 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0218566 |
| CAPRIN2 | caprin family member 2 | 0.021606 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0215042 |
| FMNL2 | formin-like 2 | 0.0214501 |
| RCOR1 | REST corepressor 1 | 0.0212852 |
| TGM2 | transglutaminase 2 | 0.0211338 |
| MED13L | mediator complex subunit 13-like | 0.0209201 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0198167 |
| PCBP2 | poly(rC) binding protein 2 | 0.0195071 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0190266 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0188669 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0184238 |
| MYOF | myoferlin | 0.0183073 |
| CD44 | CD44 molecule (Indian blood group) | 0.018157 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0179762 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0179663 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0179583 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0178785 |
| ATP13A3 | ATPase type 13A3 | 0.0177959 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0177099 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0172424 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.017101 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0170255 |
| RASAL2 | RAS protein activator like 2 | 0.0169076 |
| FLNA | filamin A, alpha | 0.016563 |
| PTK2B | protein tyrosine kinase 2 beta | 0.0165246 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0164698 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0159154 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.015536 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.015389 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0152424 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0151179 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.01482 |
| WWC1 | WW and C2 domain containing 1 | 0.0148088 |
| CUL3 | cullin 3 | 0.0147858 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0147807 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0146864 |
| FAT1 | FAT atypical cadherin 1 | 0.0145788 |
| YAP1 | Yes-associated protein 1 | 0.0145132 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.014413 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0143948 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0143678 |
| GATAD2A | GATA zinc finger domain containing 2A | 0.0140982 |
| KRT8 | keratin 8, type II | 0.0140361 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0139768 |
| CTBP2 | C-terminal binding protein 2 | 0.0138738 |
| NPTN | neuroplastin | 0.0138386 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0137738 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0137445 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0137377 |
| RALB | v-ral simian leukemia viral oncogene homolog B | 0.0137373 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0135593 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0133894 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0133411 |
| CAB39 | calcium binding protein 39 | 0.0133106 |
| CCNY | cyclin Y | 0.0133028 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.0133004 |
| ERBIN | erbb2 interacting protein | 0.0132278 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.151517 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.143243 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.140323 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.138695 |
| TXNRD1 | thioredoxin reductase 1 | -0.131891 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.116858 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.115613 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.107939 |
| LAMB3 | laminin, beta 3 | -0.104438 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.101657 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0860322 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0823961 |
| LMO7 | LIM domain 7 | -0.0812187 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0702239 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0656022 |
| MXD1 | MAX dimerization protein 1 | -0.0640616 |
| KLK10 | kallikrein-related peptidase 10 | -0.0640382 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0604545 |
| TPM4 | tropomyosin 4 | -0.0595231 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0570096 |
| TMSB10 | thymosin beta 10 | -0.0563619 |
| FTL | ferritin, light polypeptide | -0.0554727 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0543999 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0526322 |
| VIM | vimentin | -0.0517652 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0509233 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0464336 |
| TXNIP | thioredoxin interacting protein | -0.0462254 |
| CALU | calumenin | -0.0446939 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.044369 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0443161 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0435318 |
| CLMP | CXADR-like membrane protein | -0.0434353 |
| PGK1 | phosphoglycerate kinase 1 | -0.043051 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0423159 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0422163 |
| GOLGA4 | golgin A4 | -0.0420118 |
| B2M | beta-2-microglobulin | -0.0419557 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0414954 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0400535 |
| HMGA1 | high mobility group AT-hook 1 | -0.039968 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0398829 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0398441 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0398101 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0392275 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0391619 |
| ARF4 | ADP-ribosylation factor 4 | -0.0389102 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0387735 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0385347 |
| RRBP1 | ribosome binding protein 1 | -0.0377528 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0364873 |
| RPL35A | ribosomal protein L35a | -0.0363881 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0354257 |
| EGR1 | early growth response 1 | -0.0345967 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0341799 |
| FAM107B | family with sequence similarity 107, member B | -0.0340538 |
| UPP1 | uridine phosphorylase 1 | -0.0338568 |
| MORF4L2 | mortality factor 4 like 2 | -0.0329188 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0328641 |
| SP100 | SP100 nuclear antigen | -0.0324415 |
| MUC17 | mucin 17, cell surface associated | -0.0315216 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0313034 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0312472 |
| AK1 | adenylate kinase 1 | -0.0311407 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0304926 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0302409 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0301395 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.030098 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0298242 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0294722 |
| PRSS3 | protease, serine, 3 | -0.0292451 |
| GNAS | GNAS complex locus | -0.0292107 |
| TRRAP | transformation/transcription domain-associated protein | -0.0289542 |
| HLA-E | major histocompatibility complex, class I, E | -0.0289018 |
| MTDH | metadherin | -0.0287161 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0287043 |
| RPS24 | ribosomal protein S24 | -0.0283474 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0276491 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0276038 |
| PARD3 | par-3 family cell polarity regulator | -0.0275435 |
| ANXA2 | annexin A2 | -0.0275342 |
| RPL34 | ribosomal protein L34 | -0.0274137 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0273251 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.027319 |
| RPLP1 | ribosomal protein, large, P1 | -0.0271114 |
| FERMT1 | fermitin family member 1 | -0.0267911 |
| DSG2 | desmoglein 2 | -0.0267582 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0264795 |
| RIOK3 | RIO kinase 3 | -0.0264315 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0262096 |
| TAOK3 | TAO kinase 3 | -0.0260906 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0260033 |
| TMEM263 | transmembrane protein 263 | -0.0258326 |
| COG5 | component of oligomeric golgi complex 5 | -0.0255627 |
| S100A10 | S100 calcium binding protein A10 | -0.0255615 |
| RPL30 | ribosomal protein L30 | -0.0253708 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0252756 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0251696 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | -0.024896 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0247763 |
