| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clonidine (hydrochloride)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3A | fibronectin type III domain containing 3A | 0.0463894 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0410764 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0373685 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | 0.0370661 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0363556 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0278461 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0258596 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0244524 |
| PLEC | plectin | 0.0241599 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0213485 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0208918 |
| ASPH | aspartate beta-hydroxylase | 0.0193897 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0193778 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.019226 |
| SMYD3 | SET and MYND domain containing 3 | 0.0187646 |
| NTN4 | netrin 4 | 0.0180808 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0180595 |
| LRRC59 | leucine rich repeat containing 59 | 0.0176016 |
| VMP1 | vacuole membrane protein 1 | 0.0171959 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0169658 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0169445 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0166271 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0163827 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | 0.0161977 |
| DUSP16 | dual specificity phosphatase 16 | 0.0161898 |
| RPL3 | ribosomal protein L3 | 0.0159009 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0154311 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0153438 |
| AHR | aryl hydrocarbon receptor | 0.0152734 |
| MYO5B | myosin VB | 0.0152085 |
| FGB | fibrinogen beta chain | 0.0150471 |
| SMAD3 | SMAD family member 3 | 0.0150174 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0149474 |
| PPP1R9B | protein phosphatase 1, regulatory subunit 9B | 0.0140551 |
| SEPTIN9 | septin 9 | 0.0140089 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0139031 |
| SGMS1 | sphingomyelin synthase 1 | 0.013799 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0134607 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0134059 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0133585 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.0130008 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0128959 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0128642 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.0128045 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0127573 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0125358 |
| DIAPH1 | diaphanous-related formin 1 | 0.0124746 |
| ABHD17C | abhydrolase domain containing 17C | 0.0124303 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 0.0123763 |
| PLK2 | polo-like kinase 2 | 0.012216 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0121161 |
| FAM219A | family with sequence similarity 219, member A | 0.0120262 |
| SYTL2 | synaptotagmin-like 2 | 0.0116243 |
| MYO1B | myosin IB | 0.0115884 |
| FAT1 | FAT atypical cadherin 1 | 0.011377 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0112763 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0112155 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0111416 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0110855 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.011056 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0105441 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0103933 |
| NCKAP1 | NCK-associated protein 1 | 0.0103233 |
| CAB39 | calcium binding protein 39 | 0.0103124 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0100142 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.00992475 |
| KLC1 | kinesin light chain 1 | 0.00983603 |
| MED27 | mediator complex subunit 27 | 0.00951713 |
| KRT86 | keratin 86, type II | 0.00940843 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.00939022 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.00938525 |
| TNIK | TRAF2 and NCK interacting kinase | 0.00930489 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.00924883 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.00919282 |
| STK24 | serine/threonine kinase 24 | 0.00914172 |
| NPTN | neuroplastin | 0.00906751 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00899211 |
| TSC22D2 | TSC22 domain family, member 2 | 0.00895763 |
| NRP1 | neuropilin 1 | 0.00895659 |
| NCOA3 | nuclear receptor coactivator 3 | 0.00886111 |
| ACTN1 | actinin, alpha 1 | 0.00885731 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.00885307 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.00878195 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.00877924 |
| PANK3 | pantothenate kinase 3 | 0.00859872 |
| ARGLU1 | arginine and glutamate rich 1 | 0.00848186 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.00846787 |
| SAMD5 | sterile alpha motif domain containing 5 | 0.0084579 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.00824525 |
| MLPH | melanophilin | 0.00818146 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.00816751 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.00807093 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.00800866 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.00800079 |
| PHF20L1 | PHD finger protein 20-like 1 | 0.00793689 |
| EXOC6B | exocyst complex component 6B | 0.00779131 |
| STXBP4 | syntaxin binding protein 4 | 0.00770052 |
| TENM2 | teneurin transmembrane protein 2 | 0.00768216 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) | 0.00761842 |
| CYTH1 | cytohesin 1 | 0.00761597 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.255663 |
| RPL19 | ribosomal protein L19 | -0.236771 |
| RPL23 | ribosomal protein L23 | -0.181174 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.109955 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.107545 |
| PTMA | prothymosin, alpha | -0.102969 |
| ACTG1 | actin gamma 1 | -0.085623 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0669308 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0654846 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.0637706 |
| LASP1 | LIM and SH3 protein 1 | -0.0616649 |
| RPL35A | ribosomal protein L35a | -0.0603114 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0602907 |
| NDRG1 | N-myc downstream regulated 1 | -0.0591533 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0576909 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0496731 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0486394 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0474469 |
| CDK12 | cyclin-dependent kinase 12 | -0.0472408 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0468764 |
| GRB7 | growth factor receptor-bound protein 7 | -0.0467258 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0442934 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0438856 |
| RPL12 | ribosomal protein L12 | -0.0437557 |
| CCND1 | cyclin D1 | -0.0428354 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0426035 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0423913 |
| RPS3 | ribosomal protein S3 | -0.0394886 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | -0.0392303 |
| NCOA6 | nuclear receptor coactivator 6 | -0.039008 |
| LDHA | lactate dehydrogenase A | -0.0383352 |
| TMEM123 | transmembrane protein 123 | -0.0382036 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0380673 |
| RPS6 | ribosomal protein S6 | -0.0371638 |
| HLA-B | major histocompatibility complex, class I, B | -0.0365479 |
| TPM4 | tropomyosin 4 | -0.035781 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0347533 |
| RPS8 | ribosomal protein S8 | -0.0345452 |
| RPS24 | ribosomal protein S24 | -0.0339574 |
| GNAS | GNAS complex locus | -0.0337964 |
| TMSB10 | thymosin beta 10 | -0.0333846 |
| ENO1 | enolase 1, (alpha) | -0.0328963 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0317612 |
| KRT19 | keratin 19, type I | -0.0313989 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0308989 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0308169 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0307997 |
| RPS29 | ribosomal protein S29 | -0.030556 |
| TMSB4X | thymosin beta 4, X-linked | -0.0305417 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.0303657 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0302826 |
| RPL37A | ribosomal protein L37a | -0.0301596 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0300334 |
| HLA-C | major histocompatibility complex, class I, C | -0.0296169 |
| B2M | beta-2-microglobulin | -0.0291874 |
| DSTN | destrin (actin depolymerizing factor) | -0.0289576 |
| RPLP1 | ribosomal protein, large, P1 | -0.0288399 |
| RPL34 | ribosomal protein L34 | -0.0286857 |
| RPL37 | ribosomal protein L37 | -0.0281941 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0279853 |
| PFDN4 | prefoldin subunit 4 | -0.0277849 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0276246 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0268066 |
| CEP250 | centrosomal protein 250kDa | -0.0263021 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0260034 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0259242 |
| RPL11 | ribosomal protein L11 | -0.0257634 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0256859 |
| RPL31 | ribosomal protein L31 | -0.0254741 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0252552 |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | -0.0251731 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0248117 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0246848 |
| RPL27A | ribosomal protein L27a | -0.0244226 |
| FTL | ferritin, light polypeptide | -0.0243214 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0242131 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0241405 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0240832 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0240693 |
| RBM47 | RNA binding motif protein 47 | -0.0240222 |
| FDPS | farnesyl diphosphate synthase | -0.0237174 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0236043 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0230623 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0226783 |
| POTEF | POTE ankyrin domain family, member F | -0.0226453 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0225145 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0223557 |
| KRT7 | keratin 7, type II | -0.022171 |
| MTDH | metadherin | -0.0220225 |
| CANX | calnexin | -0.0220019 |
| KPNB1 | karyopherin (importin) beta 1 | -0.021991 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0219526 |
| RPS13 | ribosomal protein S13 | -0.0219458 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.021771 |
| RPL9 | ribosomal protein L9 | -0.0216765 |
| PGK1 | phosphoglycerate kinase 1 | -0.021668 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0216561 |
| RPL36 | ribosomal protein L36 | -0.0213346 |
| FASN | fatty acid synthase | -0.0212284 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0211577 |
