| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clonidine (hydrochloride)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VGF | VGF nerve growth factor inducible | 0.126917 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.112383 |
| ASPH | aspartate beta-hydroxylase | 0.106373 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.09267 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.086795 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0837998 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0814735 |
| FMNL2 | formin-like 2 | 0.0764422 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0733106 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0694662 |
| CTTNBP2 | cortactin binding protein 2 | 0.0638418 |
| DST | dystonin | 0.0625635 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0594693 |
| PTK2 | protein tyrosine kinase 2 | 0.0566227 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0559248 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0552531 |
| PRELID2 | PRELI domain containing 2 | 0.0552215 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0545648 |
| SETBP1 | SET binding protein 1 | 0.053819 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0518795 |
| TBC1D22A | TBC1 domain family, member 22A | 0.050871 |
| ATXN1 | ataxin 1 | 0.0494192 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0479826 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0476304 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0468227 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0465765 |
| ACTN1 | actinin, alpha 1 | 0.0462422 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0460305 |
| NLGN1 | neuroligin 1 | 0.0458764 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0457843 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0447124 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0433302 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0432616 |
| CALU | calumenin | 0.0432249 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0430462 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0424813 |
| PLEC | plectin | 0.0422607 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0418747 |
| NAV1 | neuron navigator 1 | 0.0407045 |
| PARVB | parvin, beta | 0.0406611 |
| AHNAK | AHNAK nucleoprotein | 0.0399933 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0399496 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0398077 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0391644 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0391351 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0390796 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0384912 |
| SEPTIN9 | septin 9 | 0.0382191 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0379536 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0378807 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0369944 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0361687 |
| TLE4 | transducin-like enhancer of split 4 | 0.0356148 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0348606 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0344243 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0339474 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0336024 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0327905 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0326302 |
| ZYX | zyxin | 0.0311554 |
| RASA3 | RAS p21 protein activator 3 | 0.0301523 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0299169 |
| CALR | calreticulin | 0.0297117 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.029283 |
| SDC2 | syndecan 2 | 0.0290417 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0289697 |
| EXOC4 | exocyst complex component 4 | 0.0288672 |
| RRBP1 | ribosome binding protein 1 | 0.0288013 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0286588 |
| CTBP2 | C-terminal binding protein 2 | 0.0281386 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0279004 |
| EXT1 | exostosin glycosyltransferase 1 | 0.027768 |
| FLNB | filamin B, beta | 0.0276475 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.027621 |
| LMNA | lamin A/C | 0.0273156 |
| ZFYVE28 | zinc finger, FYVE domain containing 28 | 0.0270232 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0268522 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0264216 |
| GPC6 | glypican 6 | 0.0264202 |
| AFAP1 | actin filament associated protein 1 | 0.026371 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0262414 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0261191 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0258851 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0257787 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0257472 |
| EFCAB13 | EF-hand calcium binding domain 13 | 0.0253974 |
| SYNM | synemin, intermediate filament protein | 0.0251829 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0251605 |
| ZNF638 | zinc finger protein 638 | 0.0244263 |
| RNF213 | ring finger protein 213 | 0.0243495 |
| ANO6 | anoctamin 6 | 0.024077 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0238986 |
| SMAD3 | SMAD family member 3 | 0.0237733 |
| INTS6 | integrator complex subunit 6 | 0.023574 |
| UTRN | utrophin | 0.0235067 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0233823 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0233188 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0233008 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0232458 |
| TPR | translocated promoter region, nuclear basket protein | 0.0232187 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.387917 |
| FN1 | fibronectin 1 | -0.181857 |
| VIM | vimentin | -0.0870257 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0843116 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0795419 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0618153 |
| TNNC1 | troponin C type 1 (slow) | -0.0592594 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0542874 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0538972 |
| EGR1 | early growth response 1 | -0.052383 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | -0.0516774 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0472892 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0461053 |
| RNF145 | ring finger protein 145 | -0.0440181 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.0419728 |
| OXR1 | oxidation resistance 1 | -0.0414655 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0402725 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0396303 |
| DCT | dopachrome tautomerase | -0.0395318 |
| POTEF | POTE ankyrin domain family, member F | -0.0391638 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0388647 |
| AHR | aryl hydrocarbon receptor | -0.0385715 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.0380624 |
| PI15 | peptidase inhibitor 15 | -0.038032 |
| RTN4 | reticulon 4 | -0.0372664 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0366911 |
| VCL | vinculin | -0.0356148 |
| GDF15 | growth differentiation factor 15 | -0.0353058 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0352123 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0348249 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0347484 |
| A2M | alpha-2-macroglobulin | -0.0328543 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0296027 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0294042 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0293834 |
| MTPN | myotrophin | -0.0292851 |
| TMEM123 | transmembrane protein 123 | -0.029109 |
| TAGLN2 | transgelin 2 | -0.0290208 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0282058 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0278431 |
| ZNF292 | zinc finger protein 292 | -0.0262521 |
| FMN1 | formin 1 | -0.0256867 |
| MT2A | metallothionein 2A | -0.0256174 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0254331 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0240249 |
| S100A6 | S100 calcium binding protein A6 | -0.0240226 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0239542 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.023812 |
| CALD1 | caldesmon 1 | -0.0231281 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0226567 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0223445 |
| SRPK2 | SRSF protein kinase 2 | -0.0222836 |
| CCNL1 | cyclin L1 | -0.0220664 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0219466 |
| ACTG1 | actin gamma 1 | -0.021876 |
| CDC73 | cell division cycle 73 | -0.0214342 |
| FOSL1 | FOS-like antigen 1 | -0.0212217 |
| HELZ | helicase with zinc finger | -0.0210474 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | -0.0207806 |
| TMEM87A | transmembrane protein 87A | -0.0205921 |
| RPLP1 | ribosomal protein, large, P1 | -0.020364 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0201956 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0201402 |
| VMP1 | vacuole membrane protein 1 | -0.0201354 |
| RLF | rearranged L-myc fusion | -0.0200985 |
| ZNF654 | zinc finger protein 654 | -0.0200702 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0200638 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0200321 |
| MITF | microphthalmia-associated transcription factor | -0.0199228 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0198208 |
| IL6ST | interleukin 6 signal transducer | -0.0198088 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0196364 |
| WDR45B | WD repeat domain 45B | -0.0195395 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0191527 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.01905 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0189223 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0188197 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0183951 |
| NUP58 | nucleoporin 58 | -0.0181902 |
| MATR3 | matrin 3 | -0.0180897 |
| CDH19 | cadherin 19, type 2 | -0.0180495 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0180225 |
| FOXJ3 | forkhead box J3 | -0.0179965 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0178885 |
| SYPL1 | synaptophysin-like 1 | -0.0177542 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0176624 |
| OSMR | oncostatin M receptor | -0.0176372 |
| CTSD | cathepsin D | -0.0174433 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0174054 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0171124 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0169701 |
| WDR43 | WD repeat domain 43 | -0.0169541 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0168708 |
| SBF2 | SET binding factor 2 | -0.0166913 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0166911 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0164369 |
| SSH1 | slingshot protein phosphatase 1 | -0.0160873 |
| INPP5F | inositol polyphosphate-5-phosphatase F | -0.0159297 |
| RHEB | Ras homolog enriched in brain | -0.0154529 |
| LDHA | lactate dehydrogenase A | -0.0154463 |
