| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clonidine (hydrochloride)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.123735 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.120044 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.107056 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.104279 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.099402 |
| SMAD3 | SMAD family member 3 | 0.0930463 |
| PLEC | plectin | 0.0905028 |
| ASPH | aspartate beta-hydroxylase | 0.0802669 |
| AHNAK | AHNAK nucleoprotein | 0.0768179 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0707099 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0700813 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0654539 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0639078 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0577198 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0532159 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0519341 |
| APOL1 | apolipoprotein L, 1 | 0.0505683 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0495694 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0493982 |
| OGA | O-GlcNAcase | 0.0487053 |
| APP | amyloid beta (A4) precursor protein | 0.0480692 |
| BICC1 | BicC family RNA binding protein 1 | 0.0465251 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0464426 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0440416 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0439138 |
| MT1X | metallothionein 1X | 0.0405952 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0405336 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.04027 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.040242 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0396278 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0392278 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0382086 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0367738 |
| AREG | amphiregulin | 0.0363937 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0360695 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0358965 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0356307 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0349746 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0338307 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.033399 |
| CANX | calnexin | 0.0325984 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0323694 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0320703 |
| FAM3C | family with sequence similarity 3, member C | 0.0319683 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0318484 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0310202 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0306905 |
| BRD2 | bromodomain containing 2 | 0.0306888 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0304533 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0304049 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0303263 |
| DSPP | dentin sialophosphoprotein | 0.0298605 |
| ARRDC3 | arrestin domain containing 3 | 0.0294795 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0292707 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0291398 |
| AHR | aryl hydrocarbon receptor | 0.0291008 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0289903 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0287525 |
| XPO1 | exportin 1 | 0.0285642 |
| PRELID2 | PRELI domain containing 2 | 0.0283966 |
| TMEM51 | transmembrane protein 51 | 0.0283462 |
| MT2A | metallothionein 2A | 0.0283175 |
| NAV2 | neuron navigator 2 | 0.0281892 |
| MYOF | myoferlin | 0.0281532 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.028115 |
| SFTPA2 | surfactant protein A2 | 0.0281122 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0279233 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0279032 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0278994 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0278884 |
| JAK1 | Janus kinase 1 | 0.0278584 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0273463 |
| TOP1 | topoisomerase (DNA) I | 0.0269898 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0265885 |
| CAPRIN2 | caprin family member 2 | 0.0263952 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0263749 |
| PDZD8 | PDZ domain containing 8 | 0.0259708 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0258755 |
| SMYD3 | SET and MYND domain containing 3 | 0.0256673 |
| RASA2 | RAS p21 protein activator 2 | 0.0252976 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0250822 |
| RBM39 | RNA binding motif protein 39 | 0.0248836 |
| NCKAP1 | NCK-associated protein 1 | 0.0248361 |
| ACTN1 | actinin, alpha 1 | 0.024527 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0244673 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0244618 |
| OLA1 | Obg-like ATPase 1 | 0.0244405 |
| CDC73 | cell division cycle 73 | 0.0242786 |
| CTBP2 | C-terminal binding protein 2 | 0.0242206 |
| RPL3 | ribosomal protein L3 | 0.0241477 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0240202 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0240168 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0240044 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0237405 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0236089 |
| FLNA | filamin A, alpha | 0.0235075 |
| KYNU | kynureninase | 0.0233785 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0231626 |
| CEP250 | centrosomal protein 250kDa | 0.0228644 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0228264 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.157206 |
| CP | ceruloplasmin (ferroxidase) | -0.142189 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.132384 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.117385 |
| HLA-B | major histocompatibility complex, class I, B | -0.0858921 |
| MMP7 | matrix metallopeptidase 7 | -0.0831124 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0819717 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.07699 |
| DTNA | dystrobrevin, alpha | -0.0760151 |
| RCOR1 | REST corepressor 1 | -0.075771 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0755092 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0707247 |
| EGR1 | early growth response 1 | -0.070703 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0702269 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0702183 |
| LAMA4 | laminin, alpha 4 | -0.0685764 |
| LAMB3 | laminin, beta 3 | -0.0678109 |
| B2M | beta-2-microglobulin | -0.0669461 |
| MCU | mitochondrial calcium uniporter | -0.0646971 |
| HLA-A | major histocompatibility complex, class I, A | -0.0645588 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0634694 |
| HMGA1 | high mobility group AT-hook 1 | -0.0633299 |
| POTEF | POTE ankyrin domain family, member F | -0.0632609 |
| NDRG1 | N-myc downstream regulated 1 | -0.0629875 |
| PARD3 | par-3 family cell polarity regulator | -0.0627132 |
| ANXA2 | annexin A2 | -0.0537967 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0533219 |
| NCKAP5 | NCK-associated protein 5 | -0.0525901 |
| KRT19 | keratin 19, type I | -0.0506378 |
| PLAT | plasminogen activator, tissue | -0.0487916 |
| S100A6 | S100 calcium binding protein A6 | -0.0485272 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0472454 |
| TMEM165 | transmembrane protein 165 | -0.0468109 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0460511 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0451671 |
| TPM4 | tropomyosin 4 | -0.0437771 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.043648 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0433194 |
| OSMR | oncostatin M receptor | -0.0430623 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0430588 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0427182 |
| TAPBP | TAP binding protein (tapasin) | -0.0420998 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0420746 |
| LAMC2 | laminin, gamma 2 | -0.0417873 |
| MUC16 | mucin 16, cell surface associated | -0.0417625 |
| PLAU | plasminogen activator, urokinase | -0.0417243 |
| PRKCA | protein kinase C, alpha | -0.0408712 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0405322 |
| CLIC4 | chloride intracellular channel 4 | -0.0404721 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.0401763 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0396984 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0396889 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0396053 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0393962 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.039241 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0388473 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.038703 |
| MUC4 | mucin 4, cell surface associated | -0.0386653 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0381148 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0379682 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0378557 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0378032 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0374398 |
| SESTD1 | SEC14 and spectrin domains 1 | -0.037193 |
| MEF2A | myocyte enhancer factor 2A | -0.0368484 |
| LAMA5 | laminin, alpha 5 | -0.03602 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | -0.035056 |
| EHBP1 | EH domain binding protein 1 | -0.0349864 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0348656 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0340851 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0339739 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0338409 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0335809 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0334301 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0334235 |
| ACTG1 | actin gamma 1 | -0.0330088 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0329461 |
| HLA-E | major histocompatibility complex, class I, E | -0.0329062 |
| GNAS | GNAS complex locus | -0.0324302 |
| RAD51B | RAD51 paralog B | -0.0322745 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.0315002 |
| RIN2 | Ras and Rab interactor 2 | -0.0312333 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0310897 |
| PCDH7 | protocadherin 7 | -0.0309802 |
| S100A10 | S100 calcium binding protein A10 | -0.0307217 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0306595 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0306513 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -0.0304631 |
| DSG2 | desmoglein 2 | -0.0304321 |
| ITGA6 | integrin, alpha 6 | -0.0302985 |
| NRG1 | neuregulin 1 | -0.0301742 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0298942 |
| VCL | vinculin | -0.0296479 |
| JUP | junction plakoglobin | -0.0295709 |
| VIM | vimentin | -0.0294633 |
| H2AC6 | H2A clustered histone 6 | -0.0293188 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0289946 |
| MX2 | MX dynamin-like GTPase 2 | -0.0288613 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0285192 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.027885 |
