| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clonidine (hydrochloride)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.163254 |
| FMN1 | formin 1 | 0.106749 |
| TLE4 | transducin-like enhancer of split 4 | 0.0793061 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0663512 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0643419 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0618245 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0597366 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0591625 |
| RNF213 | ring finger protein 213 | 0.0487927 |
| LSAMP | limbic system-associated membrane protein | 0.0475862 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0441701 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0409326 |
| RPL23 | ribosomal protein L23 | 0.0407426 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0398122 |
| TPM1 | tropomyosin 1 (alpha) | 0.0394434 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0384443 |
| STK38L | serine/threonine kinase 38 like | 0.0383221 |
| GLCCI1 | glucocorticoid induced 1 | 0.0368343 |
| VMP1 | vacuole membrane protein 1 | 0.0368338 |
| PDE10A | phosphodiesterase 10A | 0.0365735 |
| EGR1 | early growth response 1 | 0.036159 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0358229 |
| MCL1 | myeloid cell leukemia 1 | 0.0347876 |
| RPS12 | ribosomal protein S12 | 0.0335528 |
| THBS1 | thrombospondin 1 | 0.0332287 |
| RPS2 | ribosomal protein S2 | 0.03267 |
| MYO1E | myosin IE | 0.0323749 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0299197 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.029071 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0285504 |
| PLPP1 | phospholipid phosphatase 1 | 0.028531 |
| ASPH | aspartate beta-hydroxylase | 0.0282136 |
| ACTG1 | actin gamma 1 | 0.027371 |
| FERMT2 | fermitin family member 2 | 0.0269158 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0267456 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0262945 |
| KLHL13 | kelch-like family member 13 | 0.0261305 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0257301 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0248375 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0246927 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0246492 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0245349 |
| RPS6 | ribosomal protein S6 | 0.0243234 |
| RET | ret proto-oncogene | 0.024238 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.024213 |
| FAM107B | family with sequence similarity 107, member B | 0.0236757 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0235823 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0235649 |
| MED13 | mediator complex subunit 13 | 0.023198 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0231761 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0227193 |
| TPM4 | tropomyosin 4 | 0.0225844 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0225754 |
| ACTN1 | actinin, alpha 1 | 0.0225753 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0217841 |
| HOMER1 | homer scaffolding protein 1 | 0.0217196 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0217064 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.021657 |
| SIK2 | salt-inducible kinase 2 | 0.0216297 |
| TENM4 | teneurin transmembrane protein 4 | 0.0215475 |
| ITGAV | integrin, alpha V | 0.0212722 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0212645 |
| B2M | beta-2-microglobulin | 0.0211271 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.02106 |
| SET | SET nuclear proto-oncogene | 0.0209657 |
| EGFR | epidermal growth factor receptor | 0.0208863 |
| BRD2 | bromodomain containing 2 | 0.0208479 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0208409 |
| RPL35A | ribosomal protein L35a | 0.020785 |
| RIGI | RNA sensor RIG-I | 0.0206803 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0204588 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0204335 |
| CRH | corticotropin releasing hormone | 0.0203621 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0203235 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0203127 |
| RPS27A | ribosomal protein S27a | 0.0201456 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0200765 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0200533 |
| PNN | pinin, desmosome associated protein | 0.020009 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0199909 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0199647 |
| RPS17 | ribosomal protein S17 | 0.0197403 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0197283 |
| TBX2 | T-box 2 | 0.0191739 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0190438 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0189708 |
| LIMA1 | LIM domain and actin binding 1 | 0.0188697 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0188002 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.018748 |
| FHL2 | four and a half LIM domains 2 | 0.0182864 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0182264 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0181128 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0180938 |
| RPL26 | ribosomal protein L26 | 0.0180048 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0177536 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0177118 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0176596 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0174432 |
| ZNF644 | zinc finger protein 644 | 0.0173662 |
| FLNA | filamin A, alpha | 0.01656 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.507233 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.113008 |
| NRG1 | neuregulin 1 | -0.106475 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0927591 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0907959 |
| MAP1B | microtubule-associated protein 1B | -0.0652185 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0609303 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0601295 |
| VIM | vimentin | -0.0593296 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.055036 |
| NDRG1 | N-myc downstream regulated 1 | -0.0541021 |
| COL1A1 | collagen, type I, alpha 1 | -0.050753 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0503745 |
| HELZ | helicase with zinc finger | -0.045833 |
| GDF15 | growth differentiation factor 15 | -0.0443358 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0435094 |
| FAM13A | family with sequence similarity 13, member A | -0.0422804 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0415526 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0410138 |
| SYT1 | synaptotagmin I | -0.0405686 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0368371 |
| GOLGA4 | golgin A4 | -0.0364152 |
| COL3A1 | collagen, type III, alpha 1 | -0.0356882 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0355749 |
| WDR45B | WD repeat domain 45B | -0.0352113 |
| MEF2A | myocyte enhancer factor 2A | -0.0347663 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0337947 |
| ZNF804A | zinc finger protein 804A | -0.0337103 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0327601 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0326864 |
| ZNF292 | zinc finger protein 292 | -0.0325258 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0313501 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0308009 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.030683 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0302529 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0290994 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0289713 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.028625 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0283744 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0279886 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0277834 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0272288 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0268708 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0266284 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0264298 |
| GLG1 | golgi glycoprotein 1 | -0.0258898 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0258605 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0258026 |
| USP3 | ubiquitin specific peptidase 3 | -0.0254114 |
| AHR | aryl hydrocarbon receptor | -0.0253198 |
| NCAM2 | neural cell adhesion molecule 2 | -0.025123 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0249423 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0249153 |
| COPA | coatomer protein complex, subunit alpha | -0.0247769 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0246847 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0246141 |
| SRP54 | signal recognition particle 54kDa | -0.0244311 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0242348 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0240609 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0239483 |
| CLINT1 | clathrin interactor 1 | -0.0236045 |
| STC1 | stanniocalcin 1 | -0.0235693 |
| SETD5 | SET domain containing 5 | -0.0235616 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0235052 |
| CADM1 | cell adhesion molecule 1 | -0.0233597 |
| SSH2 | slingshot protein phosphatase 2 | -0.022655 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0223936 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0223843 |
| NBEA | neurobeachin | -0.0223573 |
| USP34 | ubiquitin specific peptidase 34 | -0.0222889 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0221965 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0219687 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0219389 |
| FNBP1 | formin binding protein 1 | -0.0217772 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0216716 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0216282 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0215291 |
| GPC5 | glypican 5 | -0.0214356 |
| CDC27 | cell division cycle 27 | -0.0212858 |
| HIP1 | huntingtin interacting protein 1 | -0.0212451 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0211682 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0210799 |
| C1ORF21 | chromosome 1 open reading frame 21 | -0.021036 |
| RTN4 | reticulon 4 | -0.020898 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | -0.0208805 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0208003 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0206526 |
| NREP | neuronal regeneration related protein | -0.0205589 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0205505 |
| SPAG9 | sperm associated antigen 9 | -0.0205358 |
| SEC24D | SEC24 family member D | -0.0204664 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0203021 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.020272 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0202687 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -0.0201252 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.0201249 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0201002 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0200949 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0198983 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0198354 |
