| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clonidine (hydrochloride)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.239061 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.106375 |
| SMAD3 | SMAD family member 3 | 0.103434 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0741762 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0737571 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0733783 |
| INTS6 | integrator complex subunit 6 | 0.0702923 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0642772 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.064107 |
| AREG | amphiregulin | 0.0632051 |
| EZR | ezrin | 0.0587303 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0561568 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0525771 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0499586 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0499574 |
| EFNB2 | ephrin-B2 | 0.049298 |
| ANXA2 | annexin A2 | 0.0483884 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0453046 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0433693 |
| MYO1E | myosin IE | 0.0418729 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0389902 |
| TJP1 | tight junction protein 1 | 0.038389 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0381824 |
| GOLGB1 | golgin B1 | 0.0377152 |
| DSPP | dentin sialophosphoprotein | 0.0360905 |
| ERBIN | erbb2 interacting protein | 0.0356262 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.035307 |
| SEPTIN9 | septin 9 | 0.0346315 |
| VCL | vinculin | 0.0336751 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0331124 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.032057 |
| DUSP10 | dual specificity phosphatase 10 | 0.0317694 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0316143 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0313304 |
| MLPH | melanophilin | 0.0312976 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.031144 |
| ITGA6 | integrin, alpha 6 | 0.03108 |
| FAT1 | FAT atypical cadherin 1 | 0.0308087 |
| DIAPH1 | diaphanous-related formin 1 | 0.030711 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0304952 |
| SQSTM1 | sequestosome 1 | 0.0302339 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0298641 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0298147 |
| MYO5B | myosin VB | 0.0297623 |
| SPAG9 | sperm associated antigen 9 | 0.0293979 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0286182 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0285873 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0284026 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0283554 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0283372 |
| BCL2L1 | BCL2-like 1 | 0.0277666 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0276111 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0275271 |
| MCL1 | myeloid cell leukemia 1 | 0.0274723 |
| SPATA13 | spermatogenesis associated 13 | 0.0272773 |
| PHF3 | PHD finger protein 3 | 0.0265207 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0265106 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0264117 |
| KYNU | kynureninase | 0.0262953 |
| DST | dystonin | 0.0261915 |
| SLC38A2 | solute carrier family 38, member 2 | 0.025691 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0256304 |
| HKDC1 | hexokinase domain containing 1 | 0.0250204 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0249576 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0249129 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0247303 |
| CTBP2 | C-terminal binding protein 2 | 0.0241205 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0237683 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0234875 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0231971 |
| USP53 | ubiquitin specific peptidase 53 | 0.0229888 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0218927 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0218061 |
| ASPH | aspartate beta-hydroxylase | 0.0217591 |
| LAMB3 | laminin, beta 3 | 0.0216951 |
| RDH10 | retinol dehydrogenase 10 (all-trans) | 0.0216632 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0216283 |
| TPP2 | tripeptidyl peptidase II | 0.0215203 |
| GK | glycerol kinase | 0.0214723 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0213487 |
| RAB7A | RAB7A, member RAS oncogene family | 0.021166 |
| TOP1 | topoisomerase (DNA) I | 0.0209749 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0209085 |
| CDHR2 | cadherin-related family member 2 | 0.0208525 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0207191 |
| SDC4 | syndecan 4 | 0.0207062 |
| APP | amyloid beta (A4) precursor protein | 0.0206556 |
| RND3 | Rho family GTPase 3 | 0.020531 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0202157 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0201794 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0198847 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0197763 |
| EREG | epiregulin | 0.0195183 |
| TPM3 | tropomyosin 3 | 0.0194096 |
| PLSCR2 | phospholipid scramblase 2 | 0.0192782 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0192452 |
| MCU | mitochondrial calcium uniporter | 0.0192121 |
| SIK3 | SIK family kinase 3 | 0.019022 |
| EPHA2 | EPH receptor A2 | 0.0189226 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0187472 |
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | -0.197367 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.157609 |
| HLA-B | major histocompatibility complex, class I, B | -0.1548 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.153264 |
| LCN2 | lipocalin 2 | -0.11781 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.113124 |
| TXNIP | thioredoxin interacting protein | -0.0996876 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0941366 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0928774 |
| RPL35A | ribosomal protein L35a | -0.074081 |
| NDRG1 | N-myc downstream regulated 1 | -0.0690451 |
| MT2A | metallothionein 2A | -0.0667788 |
| HLA-C | major histocompatibility complex, class I, C | -0.065111 |
| RPS6 | ribosomal protein S6 | -0.0646339 |
| TMSB10 | thymosin beta 10 | -0.0631687 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0616388 |
| RPLP1 | ribosomal protein, large, P1 | -0.0599394 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0594327 |
| FTL | ferritin, light polypeptide | -0.0583764 |
| NCKAP5 | NCK-associated protein 5 | -0.0582036 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.057628 |
| PTMA | prothymosin, alpha | -0.0566887 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0545417 |
| HLA-A | major histocompatibility complex, class I, A | -0.0505797 |
| FOXP1 | forkhead box P1 | -0.0495607 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0484842 |
| RPS19 | ribosomal protein S19 | -0.0480837 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0463808 |
| RPL12 | ribosomal protein L12 | -0.04625 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0461481 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0455722 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0450506 |
| RNF43 | ring finger protein 43 | -0.0448001 |
| RPL19 | ribosomal protein L19 | -0.0444398 |
| PERP | PERP, TP53 apoptosis effector | -0.0436544 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0429627 |
| EGR1 | early growth response 1 | -0.0419672 |
| RPL11 | ribosomal protein L11 | -0.0416935 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0414228 |
| HLA-E | major histocompatibility complex, class I, E | -0.0410784 |
| RPL23 | ribosomal protein L23 | -0.0408409 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0399422 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0386706 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.038419 |
| H3-3B | H3.3 histone B | -0.038078 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0375857 |
| RNF149 | ring finger protein 149 | -0.03739 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.03717 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0369747 |
| S100A10 | S100 calcium binding protein A10 | -0.0368738 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0354801 |
| RPS24 | ribosomal protein S24 | -0.035151 |
| XAF1 | XIAP associated factor 1 | -0.035062 |
| RPL34 | ribosomal protein L34 | -0.0350547 |
| AHI1 | Abelson helper integration site 1 | -0.0349789 |
| LOC112694756 | uncharaterized LOC112694756 | -0.034796 |
| RPL37 | ribosomal protein L37 | -0.0342939 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.034278 |
| CD46 | CD46 molecule, complement regulatory protein | -0.03418 |
| RPLP2 | ribosomal protein, large, P2 | -0.034111 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0335793 |
| RPL26 | ribosomal protein L26 | -0.0333413 |
| MT1X | metallothionein 1X | -0.032976 |
| RPL18 | ribosomal protein L18 | -0.0328591 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0328372 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0325401 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0322778 |
| RPL28 | ribosomal protein L28 | -0.0322702 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.031926 |
| ANXA4 | annexin A4 | -0.0316446 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0312491 |
| EPCAM | epithelial cell adhesion molecule | -0.0311486 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0308236 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0307333 |
| RPS27 | ribosomal protein S27 | -0.030511 |
| ITM2B | integral membrane protein 2B | -0.0301158 |
| CST3 | cystatin C | -0.0298171 |
| TMEM62 | transmembrane protein 62 | -0.0298017 |
| RPS23 | ribosomal protein S23 | -0.0294536 |
| RPS8 | ribosomal protein S8 | -0.0292126 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0291941 |
| RPL37A | ribosomal protein L37a | -0.0290066 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0289926 |
| DIAPH3 | diaphanous-related formin 3 | -0.0286922 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0282917 |
| H1-0 | H1.0 linker histone | -0.0277835 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.027699 |
| RPL31 | ribosomal protein L31 | -0.0276294 |
| TC2N | tandem C2 domains, nuclear | -0.0273311 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.027174 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.027089 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0270442 |
| RPS14 | ribosomal protein S14 | -0.0269196 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0269176 |
| CSTB | cystatin B (stefin B) | -0.0264816 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0264514 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0263023 |
| TMEM165 | transmembrane protein 165 | -0.0260744 |
| SMIM14 | small integral membrane protein 14 | -0.0256408 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0256317 |
